Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMEM121B (transmembrane protein 121B)

Identity

Alias (NCBI)CECR6
HGNC (Hugo) TMEM121B
HGNC Previous nameCECR6
HGNC Previous namecat eye syndrome chromosome region, candidate 6
LocusID (NCBI) 27439
Atlas_Id 79750
Location 22q11.1  [Link to chromosome band 22q11]
Location_base_pair Starts at 17116297 and ends at 17121360 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)TMEM121B   1844
Cards
Entrez_Gene (NCBI)TMEM121B    transmembrane protein 121B
AliasesCECR6
GeneCards (Weizmann)TMEM121B
Ensembl hg19 (Hinxton)ENSG00000183307 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183307 [Gene_View]  ENSG00000183307 [Sequence]  chr22:17116297-17121360 [Contig_View]  TMEM121B [Vega]
ICGC DataPortalENSG00000183307
TCGA cBioPortalTMEM121B
AceView (NCBI)TMEM121B
Genatlas (Paris)TMEM121B
SOURCE (Princeton)TMEM121B
Genetics Home Reference (NIH)TMEM121B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM121B  -     chr22:17116297-17121360 -  22q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM121B  -     22q11.1   [Description]    (hg19-Feb_2009)
GoldenPathTMEM121B - 22q11.1 [CytoView hg19]  TMEM121B - 22q11.1 [CytoView hg38]
ImmunoBaseENSG00000183307
Genome Data Viewer NCBITMEM121B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF307451 AK055398 AK095437 AK095609 BG472529
RefSeq transcript (Entrez)NM_001163079 NM_031890
Consensus coding sequences : CCDS (NCBI)TMEM121B
Gene ExpressionTMEM121B [ NCBI-GEO ]   TMEM121B [ EBI - ARRAY_EXPRESS ]   TMEM121B [ SEEK ]   TMEM121B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM121B [ Firebrowse - Broad ]
GenevisibleExpression of TMEM121B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27439
GTEX Portal (Tissue expression)TMEM121B
Human Protein AtlasENSG00000183307-TMEM121B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXQ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXQ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXQ6
PhosPhoSitePlusQ9BXQ6
Domains : Interpro (EBI)CECR6    CECR6/TMEM121   
Domain families : Pfam (Sanger)CECR6_TMEM121 (PF14997)   
Domain families : Pfam (NCBI)pfam14997   
Conserved Domain (NCBI)TMEM121B
SuperfamilyQ9BXQ6
AlphaFold pdb e-kbQ9BXQ6   
Human Protein Atlas [tissue]ENSG00000183307-TMEM121B [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9BXQ6
IntAct (EBI)Q9BXQ6
BioGRIDTMEM121B
STRING (EMBL)TMEM121B
ZODIACTMEM121B
Ontologies - Pathways
QuickGOQ9BXQ6
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkTMEM121B
Atlas of Cancer Signalling NetworkTMEM121B
Wikipedia pathwaysTMEM121B
Orthology - Evolution
OrthoDB27439
GeneTree (enSembl)ENSG00000183307
Phylogenetic Trees/Animal Genes : TreeFamTMEM121B
Homologs : HomoloGeneTMEM121B
Homology/Alignments : Family Browser (UCSC)TMEM121B
Gene fusions - Rearrangements
Fusion : QuiverTMEM121B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM121B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM121B
dbVarTMEM121B
ClinVarTMEM121B
MonarchTMEM121B
1000_GenomesTMEM121B 
Exome Variant ServerTMEM121B
GNOMAD BrowserENSG00000183307
Varsome BrowserTMEM121B
ACMGTMEM121B variants
VarityQ9BXQ6
Genomic Variants (DGV)TMEM121B [DGVbeta]
DECIPHERTMEM121B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM121B 
Mutations
ICGC Data PortalTMEM121B 
TCGA Data PortalTMEM121B 
Broad Tumor PortalTMEM121B
OASIS PortalTMEM121B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM121B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM121B
Mutations and Diseases : HGMDTMEM121B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM121B
DgiDB (Drug Gene Interaction Database)TMEM121B
DoCM (Curated mutations)TMEM121B
CIViC (Clinical Interpretations of Variants in Cancer)TMEM121B
Cancer3DTMEM121B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM121B
MedgenTMEM121B
Genetic Testing Registry TMEM121B
NextProtQ9BXQ6 [Medical]
GENETestsTMEM121B
Target ValidationTMEM121B
Huge Navigator TMEM121B [HugePedia]
ClinGenTMEM121B
Clinical trials, drugs, therapy
MyCancerGenomeTMEM121B
Protein Interactions : CTDTMEM121B
Pharm GKB GenePA26387
PharosQ9BXQ6
Clinical trialTMEM121B
Miscellaneous
canSAR (ICR)TMEM121B
HarmonizomeTMEM121B
DataMed IndexTMEM121B
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM121B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:25:45 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.