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TMEM126B (transmembrane protein 126B)

Identity

Alias_symbol (synonym)HT007
Other alias
HGNC (Hugo) TMEM126B
LocusID (NCBI) 55863
Atlas_Id 74788
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 85628573 and ends at 85636540 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXW7 (4q31.3) / TMEM126B (11q14.1)TMEM126B (11q14.1) / GRIA4 (11q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM126B   30883
Cards
Entrez_Gene (NCBI)TMEM126B  55863  transmembrane protein 126B
AliasesHT007
GeneCards (Weizmann)TMEM126B
Ensembl hg19 (Hinxton)ENSG00000171204 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171204 [Gene_View]  chr11:85628573-85636540 [Contig_View]  TMEM126B [Vega]
ICGC DataPortalENSG00000171204
TCGA cBioPortalTMEM126B
AceView (NCBI)TMEM126B
Genatlas (Paris)TMEM126B
WikiGenes55863
SOURCE (Princeton)TMEM126B
Genetics Home Reference (NIH)TMEM126B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM126B  -     chr11:85628573-85636540 +  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM126B  -     11q14.1   [Description]    (hg19-Feb_2009)
EnsemblTMEM126B - 11q14.1 [CytoView hg19]  TMEM126B - 11q14.1 [CytoView hg38]
Mapping of homologs : NCBITMEM126B [Mapview hg19]  TMEM126B [Mapview hg38]
OMIM252010   615533   
Gene and transcription
Genbank (Entrez)AA005078 AF220193 AF246240 AK291150 AK298189
RefSeq transcript (Entrez)NM_001193537 NM_001193538 NM_001256546 NM_001256547 NM_001350393 NM_001350394 NM_001350395 NM_001350396 NM_018480
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM126B
Cluster EST : UnigeneHs.525063 [ NCBI ]
CGAP (NCI)Hs.525063
Alternative Splicing GalleryENSG00000171204
Gene ExpressionTMEM126B [ NCBI-GEO ]   TMEM126B [ EBI - ARRAY_EXPRESS ]   TMEM126B [ SEEK ]   TMEM126B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM126B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55863
GTEX Portal (Tissue expression)TMEM126B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUX1
Splice isoforms : SwissVarQ8IUX1
PhosPhoSitePlusQ8IUX1
Domains : Interpro (EBI)TMEM126   
Domain families : Pfam (Sanger)TMEM126 (PF07114)   
Domain families : Pfam (NCBI)pfam07114   
Conserved Domain (NCBI)TMEM126B
DMDM Disease mutations55863
Blocks (Seattle)TMEM126B
SuperfamilyQ8IUX1
Human Protein AtlasENSG00000171204
Peptide AtlasQ8IUX1
HPRD13715
IPIIPI00020540   IPI00829733   IPI00830000   IPI00829966   IPI00477843   IPI00385883   IPI00979525   IPI00980202   IPI00975560   IPI00980103   IPI00976739   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUX1
IntAct (EBI)Q8IUX1
FunCoupENSG00000171204
BioGRIDTMEM126B
STRING (EMBL)TMEM126B
ZODIACTMEM126B
Ontologies - Pathways
QuickGOQ8IUX1
Ontology : AmiGOmolecular_function  protein binding  cellular_component  mitochondrion  mitochondrial inner membrane  biological_process  integral component of membrane  mitochondrial respiratory chain complex I assembly  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  mitochondrion  mitochondrial inner membrane  biological_process  integral component of membrane  mitochondrial respiratory chain complex I assembly  
NDEx NetworkTMEM126B
Atlas of Cancer Signalling NetworkTMEM126B
Wikipedia pathwaysTMEM126B
Orthology - Evolution
OrthoDB55863
GeneTree (enSembl)ENSG00000171204
Phylogenetic Trees/Animal Genes : TreeFamTMEM126B
HOVERGENQ8IUX1
HOGENOMQ8IUX1
Homologs : HomoloGeneTMEM126B
Homology/Alignments : Family Browser (UCSC)TMEM126B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM126B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM126B
dbVarTMEM126B
ClinVarTMEM126B
1000_GenomesTMEM126B 
Exome Variant ServerTMEM126B
ExAC (Exome Aggregation Consortium)TMEM126B (select the gene name)
Genetic variants : HAPMAP55863
Genomic Variants (DGV)TMEM126B [DGVbeta]
DECIPHERTMEM126B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM126B 
Mutations
ICGC Data PortalTMEM126B 
TCGA Data PortalTMEM126B 
Broad Tumor PortalTMEM126B
OASIS PortalTMEM126B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM126B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM126B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TMEM126B
DgiDB (Drug Gene Interaction Database)TMEM126B
DoCM (Curated mutations)TMEM126B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM126B (select a term)
intoGenTMEM126B
Cancer3DTMEM126B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM252010    615533   
Orphanet
MedgenTMEM126B
Genetic Testing Registry TMEM126B
NextProtQ8IUX1 [Medical]
TSGene55863
GENETestsTMEM126B
Target ValidationTMEM126B
Huge Navigator TMEM126B [HugePedia]
snp3D : Map Gene to Disease55863
BioCentury BCIQTMEM126B
ClinGenTMEM126B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55863
Chemical/Pharm GKB GenePA143485646
Clinical trialTMEM126B
Miscellaneous
canSAR (ICR)TMEM126B (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM126B
EVEXTMEM126B
GoPubMedTMEM126B
iHOPTMEM126B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:45:50 CEST 2017

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