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TMEM126B (transmembrane protein 126B)

Identity

Alias (NCBI)HT007
MC1DN29
HGNC (Hugo) TMEM126B
HGNC Alias symbHT007
LocusID (NCBI) 55863
Atlas_Id 74788
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 85628593 and ends at 85636535 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FBXW7 (4q31.3) / TMEM126B (11q14.1)TMEM126B (11q14.1) / GRIA4 (11q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM126B   30883
Cards
Entrez_Gene (NCBI)TMEM126B    transmembrane protein 126B
AliasesHT007; MC1DN29
GeneCards (Weizmann)TMEM126B
Ensembl hg19 (Hinxton)ENSG00000171204 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171204 [Gene_View]  ENSG00000171204 [Sequence]  chr11:85628593-85636535 [Contig_View]  TMEM126B [Vega]
ICGC DataPortalENSG00000171204
TCGA cBioPortalTMEM126B
AceView (NCBI)TMEM126B
Genatlas (Paris)TMEM126B
SOURCE (Princeton)TMEM126B
Genetics Home Reference (NIH)TMEM126B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM126B  -     chr11:85628593-85636535 +  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM126B  -     11q14.1   [Description]    (hg19-Feb_2009)
GoldenPathTMEM126B - 11q14.1 [CytoView hg19]  TMEM126B - 11q14.1 [CytoView hg38]
ImmunoBaseENSG00000171204
Genome Data Viewer NCBITMEM126B [Mapview hg19]  
OMIM615533   618250   
Gene and transcription
Genbank (Entrez)AA005078 AF220193 AF246240 AK291150 AK298189
RefSeq transcript (Entrez)NM_001193537 NM_001193538 NM_001256546 NM_001256547 NM_001350393 NM_001350394 NM_001350395 NM_001350396 NM_018480
Consensus coding sequences : CCDS (NCBI)TMEM126B
Gene ExpressionTMEM126B [ NCBI-GEO ]   TMEM126B [ EBI - ARRAY_EXPRESS ]   TMEM126B [ SEEK ]   TMEM126B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM126B [ Firebrowse - Broad ]
GenevisibleExpression of TMEM126B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55863
GTEX Portal (Tissue expression)TMEM126B
Human Protein AtlasENSG00000171204-TMEM126B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUX1
PhosPhoSitePlusQ8IUX1
Domains : Interpro (EBI)TMEM126   
Domain families : Pfam (Sanger)TMEM126 (PF07114)   
Domain families : Pfam (NCBI)pfam07114   
Conserved Domain (NCBI)TMEM126B
SuperfamilyQ8IUX1
AlphaFold pdb e-kbQ8IUX1   
Human Protein Atlas [tissue]ENSG00000171204-TMEM126B [tissue]
HPRD13715
Protein Interaction databases
DIP (DOE-UCLA)Q8IUX1
IntAct (EBI)Q8IUX1
BioGRIDTMEM126B
STRING (EMBL)TMEM126B
ZODIACTMEM126B
Ontologies - Pathways
QuickGOQ8IUX1
Ontology : AmiGOmolecular_function  protein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  integral component of membrane  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  
Ontology : EGO-EBImolecular_function  protein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  integral component of membrane  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  
NDEx NetworkTMEM126B
Atlas of Cancer Signalling NetworkTMEM126B
Wikipedia pathwaysTMEM126B
Orthology - Evolution
OrthoDB55863
GeneTree (enSembl)ENSG00000171204
Phylogenetic Trees/Animal Genes : TreeFamTMEM126B
Homologs : HomoloGeneTMEM126B
Homology/Alignments : Family Browser (UCSC)TMEM126B
Gene fusions - Rearrangements
Fusion : QuiverTMEM126B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM126B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM126B
dbVarTMEM126B
ClinVarTMEM126B
MonarchTMEM126B
1000_GenomesTMEM126B 
Exome Variant ServerTMEM126B
GNOMAD BrowserENSG00000171204
Varsome BrowserTMEM126B
ACMGTMEM126B variants
VarityQ8IUX1
Genomic Variants (DGV)TMEM126B [DGVbeta]
DECIPHERTMEM126B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM126B 
Mutations
ICGC Data PortalTMEM126B 
TCGA Data PortalTMEM126B 
Broad Tumor PortalTMEM126B
OASIS PortalTMEM126B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM126B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM126B
Mutations and Diseases : HGMDTMEM126B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM126B
DgiDB (Drug Gene Interaction Database)TMEM126B
DoCM (Curated mutations)TMEM126B
CIViC (Clinical Interpretations of Variants in Cancer)TMEM126B
Cancer3DTMEM126B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615533    618250   
Orphanet
DisGeNETTMEM126B
MedgenTMEM126B
Genetic Testing Registry TMEM126B
NextProtQ8IUX1 [Medical]
GENETestsTMEM126B
Target ValidationTMEM126B
Huge Navigator TMEM126B [HugePedia]
ClinGenTMEM126B
Clinical trials, drugs, therapy
MyCancerGenomeTMEM126B
Protein Interactions : CTDTMEM126B
Pharm GKB GenePA143485646
PharosQ8IUX1
Clinical trialTMEM126B
Miscellaneous
canSAR (ICR)TMEM126B
HarmonizomeTMEM126B
DataMed IndexTMEM126B
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM126B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:25:46 CEST 2021

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