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TMEM129 (transmembrane protein 129)

Identity

Alias_namestransmembrane protein 129, E3 ubiquitin protein ligase
Alias_symbol (synonym)D4S2561E
Other alias
HGNC (Hugo) TMEM129
LocusID (NCBI) 92305
Atlas_Id 74790
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 1715952 and ends at 1721357 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM129   25137
Cards
Entrez_Gene (NCBI)TMEM129  92305  transmembrane protein 129
AliasesD4S2561E
GeneCards (Weizmann)TMEM129
Ensembl hg19 (Hinxton)ENSG00000168936 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168936 [Gene_View]  chr4:1715952-1721357 [Contig_View]  TMEM129 [Vega]
ICGC DataPortalENSG00000168936
TCGA cBioPortalTMEM129
AceView (NCBI)TMEM129
Genatlas (Paris)TMEM129
WikiGenes92305
SOURCE (Princeton)TMEM129
Genetics Home Reference (NIH)TMEM129
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM129  -     chr4:1715952-1721357 -  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM129  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM129 - 4p16.3 [CytoView hg19]  TMEM129 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBITMEM129 [Mapview hg19]  TMEM129 [Mapview hg38]
OMIM615975   
Gene and transcription
Genbank (Entrez)AK098466 AK303880 AK310320 BC009331 BC018921
RefSeq transcript (Entrez)NM_001127266 NM_138385
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM129
Cluster EST : UnigeneHs.518562 [ NCBI ]
CGAP (NCI)Hs.518562
Alternative Splicing GalleryENSG00000168936
Gene ExpressionTMEM129 [ NCBI-GEO ]   TMEM129 [ EBI - ARRAY_EXPRESS ]   TMEM129 [ SEEK ]   TMEM129 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM129 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92305
GTEX Portal (Tissue expression)TMEM129
Protein : pattern, domain, 3D structure
UniProt/SwissProtA0AVI4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA0AVI4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA0AVI4
Splice isoforms : SwissVarA0AVI4
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusA0AVI4
Domains : Interpro (EBI)Tmpp129   
Domain families : Pfam (Sanger)Tmpp129 (PF10272)   
Domain families : Pfam (NCBI)pfam10272   
Conserved Domain (NCBI)TMEM129
DMDM Disease mutations92305
Blocks (Seattle)TMEM129
SuperfamilyA0AVI4
Human Protein AtlasENSG00000168936
Peptide AtlasA0AVI4
HPRD14290
IPIIPI00783798   IPI00305609   IPI00946805   IPI00946614   
Protein Interaction databases
DIP (DOE-UCLA)A0AVI4
IntAct (EBI)A0AVI4
FunCoupENSG00000168936
BioGRIDTMEM129
STRING (EMBL)TMEM129
ZODIACTMEM129
Ontologies - Pathways
QuickGOA0AVI4
Ontology : AmiGOprotein polyubiquitination  molecular_function  cellular_component  endoplasmic reticulum  endoplasmic reticulum membrane  response to unfolded protein  biological_process  integral component of membrane  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  metal ion binding  ubiquitin protein ligase activity involved in ERAD pathway  
Ontology : EGO-EBIprotein polyubiquitination  molecular_function  cellular_component  endoplasmic reticulum  endoplasmic reticulum membrane  response to unfolded protein  biological_process  integral component of membrane  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  metal ion binding  ubiquitin protein ligase activity involved in ERAD pathway  
NDEx NetworkTMEM129
Atlas of Cancer Signalling NetworkTMEM129
Wikipedia pathwaysTMEM129
Orthology - Evolution
OrthoDB92305
GeneTree (enSembl)ENSG00000168936
Phylogenetic Trees/Animal Genes : TreeFamTMEM129
HOVERGENA0AVI4
HOGENOMA0AVI4
Homologs : HomoloGeneTMEM129
Homology/Alignments : Family Browser (UCSC)TMEM129
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM129 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM129
dbVarTMEM129
ClinVarTMEM129
1000_GenomesTMEM129 
Exome Variant ServerTMEM129
ExAC (Exome Aggregation Consortium)TMEM129 (select the gene name)
Genetic variants : HAPMAP92305
Genomic Variants (DGV)TMEM129 [DGVbeta]
DECIPHERTMEM129 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM129 
Mutations
ICGC Data PortalTMEM129 
TCGA Data PortalTMEM129 
Broad Tumor PortalTMEM129
OASIS PortalTMEM129 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM129  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM129
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM129
DgiDB (Drug Gene Interaction Database)TMEM129
DoCM (Curated mutations)TMEM129 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM129 (select a term)
intoGenTMEM129
Cancer3DTMEM129(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615975   
Orphanet
MedgenTMEM129
Genetic Testing Registry TMEM129
NextProtA0AVI4 [Medical]
TSGene92305
GENETestsTMEM129
Target ValidationTMEM129
Huge Navigator TMEM129 [HugePedia]
snp3D : Map Gene to Disease92305
BioCentury BCIQTMEM129
ClinGenTMEM129
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92305
Chemical/Pharm GKB GenePA143485649
Clinical trialTMEM129
Miscellaneous
canSAR (ICR)TMEM129 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM129
EVEXTMEM129
GoPubMedTMEM129
iHOPTMEM129
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:41:39 CEST 2017

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