Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TMEM132B (transmembrane protein 132B)

Identity

Alias_symbol (synonym)KIAA1906
KIAA1786
Other alias-
HGNC (Hugo) TMEM132B
LocusID (NCBI) 114795
Atlas_Id 74793
Location 12q24.32  [Link to chromosome band 12q24]
Location_base_pair Starts at 125622452 and ends at 125662377 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C12orf66 (12q14.2) / TMEM132B (12q24.32)MON2 (12q14.1) / TMEM132B (12q24.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;12)(p25;q24) GMDS/TMEM132B

External links

Nomenclature
HGNC (Hugo)TMEM132B   29397
Cards
Entrez_Gene (NCBI)TMEM132B  114795  transmembrane protein 132B
Aliases
GeneCards (Weizmann)TMEM132B
Ensembl hg19 (Hinxton)ENSG00000139364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139364 [Gene_View]  ENSG00000139364 [Sequence]  chr12:125622452-125662377 [Contig_View]  TMEM132B [Vega]
ICGC DataPortalENSG00000139364
TCGA cBioPortalTMEM132B
AceView (NCBI)TMEM132B
Genatlas (Paris)TMEM132B
WikiGenes114795
SOURCE (Princeton)TMEM132B
Genetics Home Reference (NIH)TMEM132B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM132B  -     chr12:125622452-125662377 +  12q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM132B  -     12q24.32   [Description]    (hg19-Feb_2009)
EnsemblTMEM132B - 12q24.32 [CytoView hg19]  TMEM132B - 12q24.32 [CytoView hg38]
Mapping of homologs : NCBITMEM132B [Mapview hg19]  TMEM132B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB058689 AB067493 AK055283 AK090767 AK091512
RefSeq transcript (Entrez)NM_001286219 NM_052907
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM132B
Cluster EST : UnigeneHs.616436 [ NCBI ]
CGAP (NCI)Hs.616436
Alternative Splicing GalleryENSG00000139364
Gene ExpressionTMEM132B [ NCBI-GEO ]   TMEM132B [ EBI - ARRAY_EXPRESS ]   TMEM132B [ SEEK ]   TMEM132B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM132B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114795
GTEX Portal (Tissue expression)TMEM132B
Human Protein AtlasENSG00000139364-TMEM132B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14DG7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14DG7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14DG7
Splice isoforms : SwissVarQ14DG7
PhosPhoSitePlusQ14DG7
Domains : Interpro (EBI)TMEM132    TMEM132_C    TMEM132_M    TMEM132_N   
Domain families : Pfam (Sanger)TMEM132 (PF16070)    TMEM132D_C (PF15706)    TMEM132D_N (PF15705)   
Domain families : Pfam (NCBI)pfam16070    pfam15706    pfam15705   
Conserved Domain (NCBI)TMEM132B
DMDM Disease mutations114795
Blocks (Seattle)TMEM132B
SuperfamilyQ14DG7
Human Protein Atlas [tissue]ENSG00000139364-TMEM132B [tissue]
Peptide AtlasQ14DG7
HPRD17230
IPIIPI00044743   IPI00783391   IPI00843869   
Protein Interaction databases
DIP (DOE-UCLA)Q14DG7
IntAct (EBI)Q14DG7
FunCoupENSG00000139364
BioGRIDTMEM132B
STRING (EMBL)TMEM132B
ZODIACTMEM132B
Ontologies - Pathways
QuickGOQ14DG7
Ontology : AmiGOmolecular_function  cellular_component  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  integral component of membrane  
NDEx NetworkTMEM132B
Atlas of Cancer Signalling NetworkTMEM132B
Wikipedia pathwaysTMEM132B
Orthology - Evolution
OrthoDB114795
GeneTree (enSembl)ENSG00000139364
Phylogenetic Trees/Animal Genes : TreeFamTMEM132B
HOVERGENQ14DG7
HOGENOMQ14DG7
Homologs : HomoloGeneTMEM132B
Homology/Alignments : Family Browser (UCSC)TMEM132B
Gene fusions - Rearrangements
Fusion : QuiverTMEM132B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM132B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM132B
dbVarTMEM132B
ClinVarTMEM132B
1000_GenomesTMEM132B 
Exome Variant ServerTMEM132B
ExAC (Exome Aggregation Consortium)ENSG00000139364
GNOMAD BrowserENSG00000139364
Varsome BrowserTMEM132B
Genetic variants : HAPMAP114795
Genomic Variants (DGV)TMEM132B [DGVbeta]
DECIPHERTMEM132B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM132B 
Mutations
ICGC Data PortalTMEM132B 
TCGA Data PortalTMEM132B 
Broad Tumor PortalTMEM132B
OASIS PortalTMEM132B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM132B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM132B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM132B
DgiDB (Drug Gene Interaction Database)TMEM132B
DoCM (Curated mutations)TMEM132B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM132B (select a term)
intoGenTMEM132B
Cancer3DTMEM132B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM132B
MedgenTMEM132B
Genetic Testing Registry TMEM132B
NextProtQ14DG7 [Medical]
TSGene114795
GENETestsTMEM132B
Target ValidationTMEM132B
Huge Navigator TMEM132B [HugePedia]
snp3D : Map Gene to Disease114795
BioCentury BCIQTMEM132B
ClinGenTMEM132B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114795
Chemical/Pharm GKB GenePA143485652
Clinical trialTMEM132B
Miscellaneous
canSAR (ICR)TMEM132B (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM132B
EVEXTMEM132B
GoPubMedTMEM132B
iHOPTMEM132B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:35:12 CEST 2018
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