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TMEM135 (transmembrane protein 135)

Identity

Alias (NCBI)PMP52
HGNC (Hugo) TMEM135
HGNC Alias symbFLJ22104
LocusID (NCBI) 65084
Atlas_Id 74799
Location 11q14.2  [Link to chromosome band 11q14]
Location_base_pair Starts at 87037934 and ends at 87328824 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CKAP5 (11p11.2) / TMEM135 (11q14.2)SYTL2 (11q14.1) / TMEM135 (11q14.2)TMEM135 (11q14.2) / AAMDC (11q14.1)
TMEM135 (11q14.2) / ALDH3B2 (11q13.2)TMEM135 (11q14.2) / CCDC81 (11q14.2)TMEM135 (11q14.2) / CHEK1 (11q24.2)
TMEM135 (11q14.2) / CLMP (11q24.1)TMEM135 (11q14.2) / GPD1L (3p22.3)TMEM135 (11q14.2) / TMEM135 (11q14.2)
TMEM135 C11orf67TMEM135 CLMPTMEM135 ALDH3B2
TMEM135 CHEK1TMEM135 GPD1LSYTL2 TMEM135
CKAP5 TMEM135

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)TMEM135   26167
Cards
Entrez_Gene (NCBI)TMEM135    transmembrane protein 135
AliasesPMP52
GeneCards (Weizmann)TMEM135
Ensembl hg19 (Hinxton)ENSG00000166575 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166575 [Gene_View]  ENSG00000166575 [Sequence]  chr11:87037934-87328824 [Contig_View]  TMEM135 [Vega]
ICGC DataPortalENSG00000166575
TCGA cBioPortalTMEM135
AceView (NCBI)TMEM135
Genatlas (Paris)TMEM135
SOURCE (Princeton)TMEM135
Genetics Home Reference (NIH)TMEM135
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM135  -     chr11:87037934-87328824 +  11q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM135  -     11q14.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM135 - 11q14.2 [CytoView hg19]  TMEM135 - 11q14.2 [CytoView hg38]
ImmunoBaseENSG00000166575
Genome Data Viewer NCBITMEM135 [Mapview hg19]  
OMIM616360   
Gene and transcription
Genbank (Entrez)AF080569 AK000684 AK024853 AK025757 AK225364
RefSeq transcript (Entrez)NM_001168724 NM_022918
Consensus coding sequences : CCDS (NCBI)TMEM135
Gene ExpressionTMEM135 [ NCBI-GEO ]   TMEM135 [ EBI - ARRAY_EXPRESS ]   TMEM135 [ SEEK ]   TMEM135 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM135 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM135 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65084
GTEX Portal (Tissue expression)TMEM135
Human Protein AtlasENSG00000166575-TMEM135 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UB9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UB9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UB9
PhosPhoSitePlusQ86UB9
Domains : Interpro (EBI)Tmem135    TMEM135_N   
Domain families : Pfam (Sanger)TMEM135_C_rich (PF15982)   
Domain families : Pfam (NCBI)pfam15982   
Conserved Domain (NCBI)TMEM135
SuperfamilyQ86UB9
AlphaFold pdb e-kbQ86UB9   
Human Protein Atlas [tissue]ENSG00000166575-TMEM135 [tissue]
HPRD07978
Protein Interaction databases
DIP (DOE-UCLA)Q86UB9
IntAct (EBI)Q86UB9
BioGRIDTMEM135
STRING (EMBL)TMEM135
ZODIACTMEM135
Ontologies - Pathways
QuickGOQ86UB9
Ontology : AmiGOperoxisome  peroxisomal membrane  lipid droplet  peroxisome organization  response to cold  integral component of membrane  mitochondrial membrane  response to food  regulation of mitochondrial fission  
Ontology : EGO-EBIperoxisome  peroxisomal membrane  lipid droplet  peroxisome organization  response to cold  integral component of membrane  mitochondrial membrane  response to food  regulation of mitochondrial fission  
NDEx NetworkTMEM135
Atlas of Cancer Signalling NetworkTMEM135
Wikipedia pathwaysTMEM135
Orthology - Evolution
OrthoDB65084
GeneTree (enSembl)ENSG00000166575
Phylogenetic Trees/Animal Genes : TreeFamTMEM135
Homologs : HomoloGeneTMEM135
Homology/Alignments : Family Browser (UCSC)TMEM135
Gene fusions - Rearrangements
Fusion : QuiverTMEM135
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM135 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM135
dbVarTMEM135
ClinVarTMEM135
MonarchTMEM135
1000_GenomesTMEM135 
Exome Variant ServerTMEM135
GNOMAD BrowserENSG00000166575
Varsome BrowserTMEM135
ACMGTMEM135 variants
VarityQ86UB9
Genomic Variants (DGV)TMEM135 [DGVbeta]
DECIPHERTMEM135 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM135 
Mutations
ICGC Data PortalTMEM135 
TCGA Data PortalTMEM135 
Broad Tumor PortalTMEM135
OASIS PortalTMEM135 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM135  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM135
Mutations and Diseases : HGMDTMEM135
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM135
DgiDB (Drug Gene Interaction Database)TMEM135
DoCM (Curated mutations)TMEM135
CIViC (Clinical Interpretations of Variants in Cancer)TMEM135
Cancer3DTMEM135
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616360   
Orphanet
DisGeNETTMEM135
MedgenTMEM135
Genetic Testing Registry TMEM135
NextProtQ86UB9 [Medical]
GENETestsTMEM135
Target ValidationTMEM135
Huge Navigator TMEM135 [HugePedia]
ClinGenTMEM135
Clinical trials, drugs, therapy
MyCancerGenomeTMEM135
Protein Interactions : CTDTMEM135
Pharm GKB GenePA143485658
PharosQ86UB9
Clinical trialTMEM135
Miscellaneous
canSAR (ICR)TMEM135
HarmonizomeTMEM135
DataMed IndexTMEM135
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM135
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:25:48 CEST 2021
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