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TMEM136 (transmembrane protein 136)

Identity

Alias_symbol (synonym)MGC17839
Other alias-
HGNC (Hugo) TMEM136
LocusID (NCBI) 219902
Atlas_Id 74800
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 120325129 and ends at 120333679 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP11C (Xq27.1) / TMEM136 (11q23.3)RBSN (3p25.1) / TMEM136 (11q23.3)TMEM136 (11q23.3) / ATP11C (Xq27.1)
TMEM136 (11q23.3) / TMEM136 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

╝HR:

External links

Nomenclature
HGNC (Hugo)TMEM136   28280
Cards
Entrez_Gene (NCBI)TMEM136  219902  transmembrane protein 136
Aliases
GeneCards (Weizmann)TMEM136
Ensembl hg19 (Hinxton)ENSG00000181264 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181264 [Gene_View]  chr11:120325129-120333679 [Contig_View]  TMEM136 [Vega]
ICGC DataPortalENSG00000181264
TCGA cBioPortalTMEM136
AceView (NCBI)TMEM136
Genatlas (Paris)TMEM136
WikiGenes219902
SOURCE (Princeton)TMEM136
Genetics Home Reference (NIH)TMEM136
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM136  -     chr11:120325129-120333679 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM136  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM136 - 11q23.3 [CytoView hg19]  TMEM136 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBITMEM136 [Mapview hg19]  TMEM136 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK096207 AK128040 AK289680 AK294713 AK304086
RefSeq transcript (Entrez)NM_001198670 NM_001198671 NM_001198672 NM_001198673 NM_001198674 NM_001198675 NM_174926
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM136
Cluster EST : UnigeneHs.643516 [ NCBI ]
CGAP (NCI)Hs.643516
Alternative Splicing GalleryENSG00000181264
Gene ExpressionTMEM136 [ NCBI-GEO ]   TMEM136 [ EBI - ARRAY_EXPRESS ]   TMEM136 [ SEEK ]   TMEM136 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM136 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219902
GTEX Portal (Tissue expression)TMEM136
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZRR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZRR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZRR5
Splice isoforms : SwissVarQ6ZRR5
PhosPhoSitePlusQ6ZRR5
Domaine pattern : Prosite (Expaxy)TLC (PS50922)   
Domains : Interpro (EBI)TLC-dom   
Domain families : Pfam (Sanger)TRAM_LAG1_CLN8 (PF03798)   
Domain families : Pfam (NCBI)pfam03798   
Domain families : Smart (EMBL)TLC (SM00724)  
Conserved Domain (NCBI)TMEM136
DMDM Disease mutations219902
Blocks (Seattle)TMEM136
SuperfamilyQ6ZRR5
Human Protein AtlasENSG00000181264
Peptide AtlasQ6ZRR5
HPRD14461
IPIIPI00217915   IPI00643537   IPI00970846   IPI00970931   IPI00981062   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZRR5
IntAct (EBI)Q6ZRR5
FunCoupENSG00000181264
BioGRIDTMEM136
STRING (EMBL)TMEM136
ZODIACTMEM136
Ontologies - Pathways
QuickGOQ6ZRR5
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM136
Atlas of Cancer Signalling NetworkTMEM136
Wikipedia pathwaysTMEM136
Orthology - Evolution
OrthoDB219902
GeneTree (enSembl)ENSG00000181264
Phylogenetic Trees/Animal Genes : TreeFamTMEM136
HOVERGENQ6ZRR5
HOGENOMQ6ZRR5
Homologs : HomoloGeneTMEM136
Homology/Alignments : Family Browser (UCSC)TMEM136
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM136 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM136
dbVarTMEM136
ClinVarTMEM136
1000_GenomesTMEM136 
Exome Variant ServerTMEM136
ExAC (Exome Aggregation Consortium)TMEM136 (select the gene name)
Genetic variants : HAPMAP219902
Genomic Variants (DGV)TMEM136 [DGVbeta]
DECIPHERTMEM136 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM136 
Mutations
ICGC Data PortalTMEM136 
TCGA Data PortalTMEM136 
Broad Tumor PortalTMEM136
OASIS PortalTMEM136 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM136  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM136
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM136
DgiDB (Drug Gene Interaction Database)TMEM136
DoCM (Curated mutations)TMEM136 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM136 (select a term)
intoGenTMEM136
Cancer3DTMEM136(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMEM136
Genetic Testing Registry TMEM136
NextProtQ6ZRR5 [Medical]
TSGene219902
GENETestsTMEM136
Target ValidationTMEM136
Huge Navigator TMEM136 [HugePedia]
snp3D : Map Gene to Disease219902
BioCentury BCIQTMEM136
ClinGenTMEM136
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219902
Chemical/Pharm GKB GenePA144596257
Clinical trialTMEM136
Miscellaneous
canSAR (ICR)TMEM136 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM136
EVEXTMEM136
GoPubMedTMEM136
iHOPTMEM136
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:41:40 CEST 2017

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