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TMEM140 (transmembrane protein 140)

Identity

Alias_symbol (synonym)FLJ11000
Other alias-
HGNC (Hugo) TMEM140
LocusID (NCBI) 55281
Atlas_Id 74803
Location 7q33  [Link to chromosome band 7q33]
Location_base_pair Starts at 135148014 and ends at 135166215 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM140   21870
Cards
Entrez_Gene (NCBI)TMEM140  55281  transmembrane protein 140
Aliases
GeneCards (Weizmann)TMEM140
Ensembl hg19 (Hinxton)ENSG00000146859 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146859 [Gene_View]  chr7:135148014-135166215 [Contig_View]  TMEM140 [Vega]
ICGC DataPortalENSG00000146859
TCGA cBioPortalTMEM140
AceView (NCBI)TMEM140
Genatlas (Paris)TMEM140
WikiGenes55281
SOURCE (Princeton)TMEM140
Genetics Home Reference (NIH)TMEM140
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM140  -     chr7:135148014-135166215 +  7q33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM140  -     7q33   [Description]    (hg19-Feb_2009)
EnsemblTMEM140 - 7q33 [CytoView hg19]  TMEM140 - 7q33 [CytoView hg38]
Mapping of homologs : NCBITMEM140 [Mapview hg19]  TMEM140 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001862 AK225055 AK301268 BC020942 BM512090
RefSeq transcript (Entrez)NM_018295
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM140
Cluster EST : UnigeneHs.521213 [ NCBI ]
CGAP (NCI)Hs.521213
Alternative Splicing GalleryENSG00000146859
Gene ExpressionTMEM140 [ NCBI-GEO ]   TMEM140 [ EBI - ARRAY_EXPRESS ]   TMEM140 [ SEEK ]   TMEM140 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM140 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55281
GTEX Portal (Tissue expression)TMEM140
Human Protein AtlasENSG00000146859-TMEM140 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NV12   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NV12  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NV12
Splice isoforms : SwissVarQ9NV12
PhosPhoSitePlusQ9NV12
Domains : Interpro (EBI)TM140   
Domain families : Pfam (Sanger)TM140 (PF14985)   
Domain families : Pfam (NCBI)pfam14985   
Conserved Domain (NCBI)TMEM140
DMDM Disease mutations55281
Blocks (Seattle)TMEM140
SuperfamilyQ9NV12
Human Protein Atlas [tissue]ENSG00000146859-TMEM140 [tissue]
Peptide AtlasQ9NV12
HPRD07723
IPIIPI00550109   IPI00908712   IPI00880161   
Protein Interaction databases
DIP (DOE-UCLA)Q9NV12
IntAct (EBI)Q9NV12
FunCoupENSG00000146859
BioGRIDTMEM140
STRING (EMBL)TMEM140
ZODIACTMEM140
Ontologies - Pathways
QuickGOQ9NV12
Ontology : AmiGOprotein binding  integral component of membrane  
Ontology : EGO-EBIprotein binding  integral component of membrane  
NDEx NetworkTMEM140
Atlas of Cancer Signalling NetworkTMEM140
Wikipedia pathwaysTMEM140
Orthology - Evolution
OrthoDB55281
GeneTree (enSembl)ENSG00000146859
Phylogenetic Trees/Animal Genes : TreeFamTMEM140
HOVERGENQ9NV12
HOGENOMQ9NV12
Homologs : HomoloGeneTMEM140
Homology/Alignments : Family Browser (UCSC)TMEM140
Gene fusions - Rearrangements
Fusion: Tumor Portal TMEM140
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM140 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM140
dbVarTMEM140
ClinVarTMEM140
1000_GenomesTMEM140 
Exome Variant ServerTMEM140
ExAC (Exome Aggregation Consortium)ENSG00000146859
GNOMAD BrowserENSG00000146859
Genetic variants : HAPMAP55281
Genomic Variants (DGV)TMEM140 [DGVbeta]
DECIPHERTMEM140 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM140 
Mutations
ICGC Data PortalTMEM140 
TCGA Data PortalTMEM140 
Broad Tumor PortalTMEM140
OASIS PortalTMEM140 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM140  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM140
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM140
DgiDB (Drug Gene Interaction Database)TMEM140
DoCM (Curated mutations)TMEM140 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM140 (select a term)
intoGenTMEM140
Cancer3DTMEM140(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMEM140
Genetic Testing Registry TMEM140
NextProtQ9NV12 [Medical]
TSGene55281
GENETestsTMEM140
Target ValidationTMEM140
Huge Navigator TMEM140 [HugePedia]
snp3D : Map Gene to Disease55281
BioCentury BCIQTMEM140
ClinGenTMEM140
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55281
Chemical/Pharm GKB GenePA144596261
Clinical trialTMEM140
Miscellaneous
canSAR (ICR)TMEM140 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM140
EVEXTMEM140
GoPubMedTMEM140
iHOPTMEM140
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:32:44 CET 2017

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