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TMEM14A (transmembrane protein 14A)

Identity

Alias (NCBI)C6orf73
PTD011
HGNC (Hugo) TMEM14A
HGNC Alias symbPTD011
C6orf73
LocusID (NCBI) 28978
Atlas_Id 56646
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52671113 and ends at 52686587 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM14A (6p12.2) / TMEM14A (6p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM14A   21076
Cards
Entrez_Gene (NCBI)TMEM14A    transmembrane protein 14A
AliasesC6orf73; PTD011
GeneCards (Weizmann)TMEM14A
Ensembl hg19 (Hinxton)ENSG00000096092 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000096092 [Gene_View]  ENSG00000096092 [Sequence]  chr6:52671113-52686587 [Contig_View]  TMEM14A [Vega]
ICGC DataPortalENSG00000096092
TCGA cBioPortalTMEM14A
AceView (NCBI)TMEM14A
Genatlas (Paris)TMEM14A
SOURCE (Princeton)TMEM14A
Genetics Home Reference (NIH)TMEM14A
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM14A  -     chr6:52671113-52686587 +  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM14A  -     6p12.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM14A - 6p12.2 [CytoView hg19]  TMEM14A - 6p12.2 [CytoView hg38]
ImmunoBaseENSG00000096092
Genome Data Viewer NCBITMEM14A [Mapview hg19]  
OMIM616870   
Gene and transcription
Genbank (Entrez)AF078864 AF239771 AK312063 BC015097 BC019328
RefSeq transcript (Entrez)NM_014051
Consensus coding sequences : CCDS (NCBI)TMEM14A
Gene ExpressionTMEM14A [ NCBI-GEO ]   TMEM14A [ EBI - ARRAY_EXPRESS ]   TMEM14A [ SEEK ]   TMEM14A [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM14A [ Firebrowse - Broad ]
GenevisibleExpression of TMEM14A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28978
GTEX Portal (Tissue expression)TMEM14A
Human Protein AtlasENSG00000096092-TMEM14A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6G1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6G1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6G1
PhosPhoSitePlusQ9Y6G1
Domains : Interpro (EBI)TMEM14   
Domain families : Pfam (Sanger)Tmemb_14 (PF03647)   
Domain families : Pfam (NCBI)pfam03647   
Conserved Domain (NCBI)TMEM14A
PDB (RSDB)2LOO    2LOP   
PDB Europe2LOO    2LOP   
PDB (PDBSum)2LOO    2LOP   
PDB (IMB)2LOO    2LOP   
Structural Biology KnowledgeBase2LOO    2LOP   
SCOP (Structural Classification of Proteins)2LOO    2LOP   
CATH (Classification of proteins structures)2LOO    2LOP   
SuperfamilyQ9Y6G1
AlphaFold pdb e-kbQ9Y6G1   
Human Protein Atlas [tissue]ENSG00000096092-TMEM14A [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6G1
IntAct (EBI)Q9Y6G1
BioGRIDTMEM14A
STRING (EMBL)TMEM14A
ZODIACTMEM14A
Ontologies - Pathways
QuickGOQ9Y6G1
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  mitochondrial transport  apoptotic process  integral component of membrane  mitochondrial membrane  mitochondrial membrane  negative regulation of apoptotic process  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  mitochondrial transport  apoptotic process  integral component of membrane  mitochondrial membrane  mitochondrial membrane  negative regulation of apoptotic process  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  
NDEx NetworkTMEM14A
Atlas of Cancer Signalling NetworkTMEM14A
Wikipedia pathwaysTMEM14A
Orthology - Evolution
OrthoDB28978
GeneTree (enSembl)ENSG00000096092
Phylogenetic Trees/Animal Genes : TreeFamTMEM14A
Homologs : HomoloGeneTMEM14A
Homology/Alignments : Family Browser (UCSC)TMEM14A
Gene fusions - Rearrangements
Fusion : QuiverTMEM14A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM14A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM14A
dbVarTMEM14A
ClinVarTMEM14A
MonarchTMEM14A
1000_GenomesTMEM14A 
Exome Variant ServerTMEM14A
GNOMAD BrowserENSG00000096092
Varsome BrowserTMEM14A
ACMGTMEM14A variants
VarityQ9Y6G1
Genomic Variants (DGV)TMEM14A [DGVbeta]
DECIPHERTMEM14A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM14A 
Mutations
ICGC Data PortalTMEM14A 
TCGA Data PortalTMEM14A 
Broad Tumor PortalTMEM14A
OASIS PortalTMEM14A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM14A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM14A
Mutations and Diseases : HGMDTMEM14A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM14A
DgiDB (Drug Gene Interaction Database)TMEM14A
DoCM (Curated mutations)TMEM14A
CIViC (Clinical Interpretations of Variants in Cancer)TMEM14A
Cancer3DTMEM14A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616870   
Orphanet
DisGeNETTMEM14A
MedgenTMEM14A
Genetic Testing Registry TMEM14A
NextProtQ9Y6G1 [Medical]
GENETestsTMEM14A
Target ValidationTMEM14A
Huge Navigator TMEM14A [HugePedia]
ClinGenTMEM14A
Clinical trials, drugs, therapy
MyCancerGenomeTMEM14A
Protein Interactions : CTDTMEM14A
Pharm GKB GenePA134974524
PharosQ9Y6G1
Clinical trialTMEM14A
Miscellaneous
canSAR (ICR)TMEM14A
HarmonizomeTMEM14A
DataMed IndexTMEM14A
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM14A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:25 CEST 2021

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