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TMEM14A (transmembrane protein 14A)

Identity

Other aliasC6orf73
PTD011
HGNC (Hugo) TMEM14A
LocusID (NCBI) 28978
Atlas_Id 56646
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52671086 and ends at 52686587 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM14A (6p12.2) / TMEM14A (6p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM14A   21076
Cards
Entrez_Gene (NCBI)TMEM14A  28978  transmembrane protein 14A
AliasesC6orf73; PTD011
GeneCards (Weizmann)TMEM14A
Ensembl hg19 (Hinxton)ENSG00000096092 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000096092 [Gene_View]  ENSG00000096092 [Sequence]  chr6:52671086-52686587 [Contig_View]  TMEM14A [Vega]
ICGC DataPortalENSG00000096092
TCGA cBioPortalTMEM14A
AceView (NCBI)TMEM14A
Genatlas (Paris)TMEM14A
WikiGenes28978
SOURCE (Princeton)TMEM14A
Genetics Home Reference (NIH)TMEM14A
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM14A  -     chr6:52671086-52686587 +  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM14A  -     6p12.2   [Description]    (hg19-Feb_2009)
EnsemblTMEM14A - 6p12.2 [CytoView hg19]  TMEM14A - 6p12.2 [CytoView hg38]
Mapping of homologs : NCBITMEM14A [Mapview hg19]  TMEM14A [Mapview hg38]
OMIM616870   
Gene and transcription
Genbank (Entrez)AF078864 AF239771 AK312063 BC015097 BC019328
RefSeq transcript (Entrez)NM_014051
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM14A
Cluster EST : UnigeneHs.94896 [ NCBI ]
CGAP (NCI)Hs.94896
Alternative Splicing GalleryENSG00000096092
Gene ExpressionTMEM14A [ NCBI-GEO ]   TMEM14A [ EBI - ARRAY_EXPRESS ]   TMEM14A [ SEEK ]   TMEM14A [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM14A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28978
GTEX Portal (Tissue expression)TMEM14A
Human Protein AtlasENSG00000096092-TMEM14A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6G1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6G1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6G1
Splice isoforms : SwissVarQ9Y6G1
PhosPhoSitePlusQ9Y6G1
Domains : Interpro (EBI)TMEM14   
Domain families : Pfam (Sanger)Tmemb_14 (PF03647)   
Domain families : Pfam (NCBI)pfam03647   
Conserved Domain (NCBI)TMEM14A
DMDM Disease mutations28978
Blocks (Seattle)TMEM14A
PDB (SRS)2LOO    2LOP   
PDB (PDBSum)2LOO    2LOP   
PDB (IMB)2LOO    2LOP   
PDB (RSDB)2LOO    2LOP   
Structural Biology KnowledgeBase2LOO    2LOP   
SCOP (Structural Classification of Proteins)2LOO    2LOP   
CATH (Classification of proteins structures)2LOO    2LOP   
SuperfamilyQ9Y6G1
Human Protein Atlas [tissue]ENSG00000096092-TMEM14A [tissue]
Peptide AtlasQ9Y6G1
IPIIPI00002253   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6G1
IntAct (EBI)Q9Y6G1
FunCoupENSG00000096092
BioGRIDTMEM14A
STRING (EMBL)TMEM14A
ZODIACTMEM14A
Ontologies - Pathways
QuickGOQ9Y6G1
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  apoptotic process  integral component of membrane  mitochondrial membrane  negative regulation of apoptotic process  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  apoptotic process  integral component of membrane  mitochondrial membrane  negative regulation of apoptotic process  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  
NDEx NetworkTMEM14A
Atlas of Cancer Signalling NetworkTMEM14A
Wikipedia pathwaysTMEM14A
Orthology - Evolution
OrthoDB28978
GeneTree (enSembl)ENSG00000096092
Phylogenetic Trees/Animal Genes : TreeFamTMEM14A
HOVERGENQ9Y6G1
HOGENOMQ9Y6G1
Homologs : HomoloGeneTMEM14A
Homology/Alignments : Family Browser (UCSC)TMEM14A
Gene fusions - Rearrangements
Fusion : QuiverTMEM14A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM14A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM14A
dbVarTMEM14A
ClinVarTMEM14A
1000_GenomesTMEM14A 
Exome Variant ServerTMEM14A
ExAC (Exome Aggregation Consortium)ENSG00000096092
GNOMAD BrowserENSG00000096092
Varsome BrowserTMEM14A
Genetic variants : HAPMAP28978
Genomic Variants (DGV)TMEM14A [DGVbeta]
DECIPHERTMEM14A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM14A 
Mutations
ICGC Data PortalTMEM14A 
TCGA Data PortalTMEM14A 
Broad Tumor PortalTMEM14A
OASIS PortalTMEM14A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM14A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM14A
BioMutasearch TMEM14A
DgiDB (Drug Gene Interaction Database)TMEM14A
DoCM (Curated mutations)TMEM14A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM14A (select a term)
intoGenTMEM14A
Cancer3DTMEM14A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616870   
Orphanet
DisGeNETTMEM14A
MedgenTMEM14A
Genetic Testing Registry TMEM14A
NextProtQ9Y6G1 [Medical]
TSGene28978
GENETestsTMEM14A
Target ValidationTMEM14A
Huge Navigator TMEM14A [HugePedia]
snp3D : Map Gene to Disease28978
BioCentury BCIQTMEM14A
ClinGenTMEM14A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28978
Chemical/Pharm GKB GenePA134974524
Clinical trialTMEM14A
Miscellaneous
canSAR (ICR)TMEM14A (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM14A
EVEXTMEM14A
GoPubMedTMEM14A
iHOPTMEM14A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 6 11:45:28 CET 2018

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