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TMEM159 (transmembrane protein 159)

Identity

Alias_symbol (synonym)promethin
Other alias-
HGNC (Hugo) TMEM159
LocusID (NCBI) 57146
Atlas_Id 74821
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 21169698 and ends at 21191937 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
JAK2 (9p24.1) / TMEM159 (16p12.3)TMEM159 (16p12.3) / DNAH3 (16p12.3)UBFD1 (16p12.2) / TMEM159 (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM159   30136
Cards
Entrez_Gene (NCBI)TMEM159  57146  transmembrane protein 159
Aliases
GeneCards (Weizmann)TMEM159
Ensembl hg19 (Hinxton)ENSG00000011638 [Gene_View]  chr16:21169698-21191937 [Contig_View]  TMEM159 [Vega]
Ensembl hg38 (Hinxton)ENSG00000011638 [Gene_View]  chr16:21169698-21191937 [Contig_View]  TMEM159 [Vega]
ICGC DataPortalENSG00000011638
TCGA cBioPortalTMEM159
AceView (NCBI)TMEM159
Genatlas (Paris)TMEM159
WikiGenes57146
SOURCE (Princeton)TMEM159
Genetics Home Reference (NIH)TMEM159
Genomic and cartography
GoldenPath hg19 (UCSC)TMEM159  -     chr16:21169698-21191937 +  16p12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMEM159  -     16p12.3   [Description]    (hg38-Dec_2013)
EnsemblTMEM159 - 16p12.3 [CytoView hg19]  TMEM159 - 16p12.3 [CytoView hg38]
Mapping of homologs : NCBITMEM159 [Mapview hg19]  TMEM159 [Mapview hg38]
OMIM611304   
Gene and transcription
Genbank (Entrez)AF070596 AI968069 AK074667 AK293557 AL694739
RefSeq transcript (Entrez)NM_001301769 NM_001301771 NM_001301773 NM_001301774 NM_001301775 NM_020422
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_187260 NW_004929400
Consensus coding sequences : CCDS (NCBI)TMEM159
Cluster EST : UnigeneHs.258212 [ NCBI ]
CGAP (NCI)Hs.258212
Alternative Splicing GalleryENSG00000011638
Gene ExpressionTMEM159 [ NCBI-GEO ]   TMEM159 [ EBI - ARRAY_EXPRESS ]   TMEM159 [ SEEK ]   TMEM159 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM159 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57146
GTEX Portal (Tissue expression)TMEM159
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B96   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96B96  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96B96
Splice isoforms : SwissVarQ96B96
PhosPhoSitePlusQ96B96
Domains : Interpro (EBI)Promethin/TMEM159   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM159
DMDM Disease mutations57146
Blocks (Seattle)TMEM159
SuperfamilyQ96B96
Human Protein AtlasENSG00000011638
Peptide AtlasQ96B96
HPRD17428
IPIIPI00298405   IPI00646518   
Protein Interaction databases
DIP (DOE-UCLA)Q96B96
IntAct (EBI)Q96B96
FunCoupENSG00000011638
BioGRIDTMEM159
STRING (EMBL)TMEM159
ZODIACTMEM159
Ontologies - Pathways
QuickGOQ96B96
Ontology : AmiGOprotein binding  integral component of membrane  
Ontology : EGO-EBIprotein binding  integral component of membrane  
NDEx NetworkTMEM159
Atlas of Cancer Signalling NetworkTMEM159
Wikipedia pathwaysTMEM159
Orthology - Evolution
OrthoDB57146
GeneTree (enSembl)ENSG00000011638
Phylogenetic Trees/Animal Genes : TreeFamTMEM159
HOVERGENQ96B96
HOGENOMQ96B96
Homologs : HomoloGeneTMEM159
Homology/Alignments : Family Browser (UCSC)TMEM159
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM159 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM159
dbVarTMEM159
ClinVarTMEM159
1000_GenomesTMEM159 
Exome Variant ServerTMEM159
ExAC (Exome Aggregation Consortium)TMEM159 (select the gene name)
Genetic variants : HAPMAP57146
Genomic Variants (DGV)TMEM159 [DGVbeta]
DECIPHER (Syndromes)16:21169698-21191937  ENSG00000011638
CONAN: Copy Number AnalysisTMEM159 
Mutations
ICGC Data PortalTMEM159 
TCGA Data PortalTMEM159 
Broad Tumor PortalTMEM159
OASIS PortalTMEM159 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM159  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM159
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM159
DgiDB (Drug Gene Interaction Database)TMEM159
DoCM (Curated mutations)TMEM159 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM159 (select a term)
intoGenTMEM159
Cancer3DTMEM159(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611304   
Orphanet
MedgenTMEM159
Genetic Testing Registry TMEM159
NextProtQ96B96 [Medical]
TSGene57146
GENETestsTMEM159
Huge Navigator TMEM159 [HugePedia]
snp3D : Map Gene to Disease57146
BioCentury BCIQTMEM159
ClinGenTMEM159
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57146
Chemical/Pharm GKB GenePA145147935
Clinical trialTMEM159
Miscellaneous
canSAR (ICR)TMEM159 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM159
EVEXTMEM159
GoPubMedTMEM159
iHOPTMEM159
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:48:31 CET 2017

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