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TMEM161B (transmembrane protein 161B)

Identity

Alias_symbol (synonym)MGC33214
Other aliasFLB3342
PRO1313
HGNC (Hugo) TMEM161B
LocusID (NCBI) 153396
Atlas_Id 74823
Location 5q14.3  [Link to chromosome band 5q14]
Location_base_pair Starts at 88189633 and ends at 88268879 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLIP1 (12q24.31) / TMEM161B (5q14.3)PPIP5K2 (5q21.1) / TMEM161B (5q14.3)TMEM161B (5q14.3) / CETN3 (5q14.3)
TMEM161B (5q14.3) / FAM81B (5q15)TMEM161B (5q14.3) / TMEM161B (5q14.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;5)(q14;q15) TMEM161B/FAM81B

External links

Nomenclature
HGNC (Hugo)TMEM161B   28483
Cards
Entrez_Gene (NCBI)TMEM161B  153396  transmembrane protein 161B
AliasesFLB3342; PRO1313
GeneCards (Weizmann)TMEM161B
Ensembl hg19 (Hinxton)ENSG00000164180 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164180 [Gene_View]  chr5:88189633-88268879 [Contig_View]  TMEM161B [Vega]
ICGC DataPortalENSG00000164180
TCGA cBioPortalTMEM161B
AceView (NCBI)TMEM161B
Genatlas (Paris)TMEM161B
WikiGenes153396
SOURCE (Princeton)TMEM161B
Genetics Home Reference (NIH)TMEM161B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM161B  -     chr5:88189633-88268879 -  5q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM161B  -     5q14.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM161B - 5q14.3 [CytoView hg19]  TMEM161B - 5q14.3 [CytoView hg38]
Mapping of homologs : NCBITMEM161B [Mapview hg19]  TMEM161B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI570193 AK299896 AK300006 AK300893 AK301091
RefSeq transcript (Entrez)NM_001289007 NM_001289008 NM_001349400 NM_001349402 NM_001349403 NM_001349405 NM_001349407 NM_153354
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM161B
Cluster EST : UnigeneHs.379972 [ NCBI ]
CGAP (NCI)Hs.379972
Alternative Splicing GalleryENSG00000164180
Gene ExpressionTMEM161B [ NCBI-GEO ]   TMEM161B [ EBI - ARRAY_EXPRESS ]   TMEM161B [ SEEK ]   TMEM161B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM161B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)153396
GTEX Portal (Tissue expression)TMEM161B
Human Protein AtlasENSG00000164180-TMEM161B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NDZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NDZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NDZ6
Splice isoforms : SwissVarQ8NDZ6
PhosPhoSitePlusQ8NDZ6
Domains : Interpro (EBI)Transmembrane_161A/B   
Domain families : Pfam (Sanger)Tmemb_161AB (PF10268)   
Domain families : Pfam (NCBI)pfam10268   
Conserved Domain (NCBI)TMEM161B
DMDM Disease mutations153396
Blocks (Seattle)TMEM161B
SuperfamilyQ8NDZ6
Human Protein Atlas [tissue]ENSG00000164180-TMEM161B [tissue]
Peptide AtlasQ8NDZ6
HPRD14555
IPIIPI00181160   IPI00848253   IPI01018314   IPI00965054   IPI00964745   IPI00922850   IPI00968191   IPI00964449   IPI00921829   
Protein Interaction databases
DIP (DOE-UCLA)Q8NDZ6
IntAct (EBI)Q8NDZ6
FunCoupENSG00000164180
BioGRIDTMEM161B
STRING (EMBL)TMEM161B
ZODIACTMEM161B
Ontologies - Pathways
QuickGOQ8NDZ6
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM161B
Atlas of Cancer Signalling NetworkTMEM161B
Wikipedia pathwaysTMEM161B
Orthology - Evolution
OrthoDB153396
GeneTree (enSembl)ENSG00000164180
Phylogenetic Trees/Animal Genes : TreeFamTMEM161B
HOVERGENQ8NDZ6
HOGENOMQ8NDZ6
Homologs : HomoloGeneTMEM161B
Homology/Alignments : Family Browser (UCSC)TMEM161B
Gene fusions - Rearrangements
Fusion : QuiverTMEM161B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM161B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM161B
dbVarTMEM161B
ClinVarTMEM161B
1000_GenomesTMEM161B 
Exome Variant ServerTMEM161B
ExAC (Exome Aggregation Consortium)ENSG00000164180
GNOMAD BrowserENSG00000164180
Genetic variants : HAPMAP153396
Genomic Variants (DGV)TMEM161B [DGVbeta]
DECIPHERTMEM161B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM161B 
Mutations
ICGC Data PortalTMEM161B 
TCGA Data PortalTMEM161B 
Broad Tumor PortalTMEM161B
OASIS PortalTMEM161B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM161B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM161B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM161B
DgiDB (Drug Gene Interaction Database)TMEM161B
DoCM (Curated mutations)TMEM161B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM161B (select a term)
intoGenTMEM161B
Cancer3DTMEM161B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM161B
MedgenTMEM161B
Genetic Testing Registry TMEM161B
NextProtQ8NDZ6 [Medical]
TSGene153396
GENETestsTMEM161B
Target ValidationTMEM161B
Huge Navigator TMEM161B [HugePedia]
snp3D : Map Gene to Disease153396
BioCentury BCIQTMEM161B
ClinGenTMEM161B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD153396
Chemical/Pharm GKB GenePA145147987
Clinical trialTMEM161B
Miscellaneous
canSAR (ICR)TMEM161B (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM161B
EVEXTMEM161B
GoPubMedTMEM161B
iHOPTMEM161B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:55:50 CET 2018
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