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TMEM18 (transmembrane protein 18)

Identity

Alias_symbol (synonym)DKFZp434C1714
Other alias-
HGNC (Hugo) TMEM18
LocusID (NCBI) 129787
Atlas_Id 53977
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 667973 and ends at 677439 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM18 (2p25.3) / TLE3 (15q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

BioGRID
Nomenclature
HGNC (Hugo)TMEM18   25257
Cards
Entrez_Gene (NCBI)TMEM18  129787  transmembrane protein 18
Aliases
GeneCards (Weizmann)TMEM18
Ensembl hg19 (Hinxton)ENSG00000151353 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151353 [Gene_View]  chr2:667973-677439 [Contig_View]  TMEM18 [Vega]
ICGC DataPortalENSG00000151353
TCGA cBioPortalTMEM18
AceView (NCBI)TMEM18
Genatlas (Paris)TMEM18
WikiGenes129787
SOURCE (Princeton)TMEM18
Genetics Home Reference (NIH)TMEM18
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM18  -     chr2:667973-677439 -  2p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM18  -     2p25.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM18 - 2p25.3 [CytoView hg19]  TMEL10 - 2p25.3 [CytoView hg38]
Mapping of homologs : NCBITMEM18 [Mapview hg19]  TMEM18 [Mapview hg38]
OMIM613220   
Gene and transcription
Genbank (Entrez)AK125009 AL137269 BC016010 BC032379 BC040373
RefSeq transcript (Entrez)NM_152834
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM18
Cluster EST : UnigeneHs.43899 [ NCBI ]
CGAP (NCI)Hs.43899
Alternative Splicing GalleryENSG00000151353
Gene ExpressionTMEM18 [ NCBI-GEO ]   TMEM18 [ EBI - ARRAY_EXPRESS ]   TMEM18 [ SEEK ]   TMEM18 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)129787
GTEX Portal (Tissue expression)TMEM18
Human Protein AtlasENSG00000151353-TMEM18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B42   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96B42  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96B42
Splice isoforms : SwissVarQ96B42
PhosPhoSitePlusQ96B42
Domains : Interpro (EBI)TMEM18   
Domain families : Pfam (Sanger)TMEM18 (PF14770)   
Domain families : Pfam (NCBI)pfam14770   
Conserved Domain (NCBI)TMEM18
DMDM Disease mutations129787
Blocks (Seattle)TMEM18
SuperfamilyQ96B42
Human Protein Atlas [tissue]ENSG00000151353-TMEM18 [tissue]
Peptide AtlasQ96B42
HPRD15529
IPIIPI00004833   IPI00892618   IPI00477116   IPI00894379   
Protein Interaction databases
DIP (DOE-UCLA)Q96B42
IntAct (EBI)Q96B42
FunCoupENSG00000151353
TMEM18
STRING (EMBL)TMEM18
ZODIACTMEM18
Ontologies - Pathways
QuickGOQ96B42
Ontology : AmiGODNA binding  cytoplasm  transcription, DNA-templated  integral component of membrane  cell migration  nuclear membrane  
Ontology : EGO-EBIDNA binding  cytoplasm  transcription, DNA-templated  integral component of membrane  cell migration  nuclear membrane  
NDEx NetworkTMEM18
Atlas of Cancer Signalling NetworkTMEM18
Wikipedia pathwaysTMEM18
Orthology - Evolution
OrthoDB129787
GeneTree (enSembl)ENSG00000151353
Phylogenetic Trees/Animal Genes : TreeFamTMEM18
HOVERGENQ96B42
HOGENOMQ96B42
Homologs : HomoloGeneTMEM18
Homology/Alignments : Family Browser (UCSC)TMEM18
Gene fusions - Rearrangements
Tumor Fusion PortalTMEM18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM18
dbVarTMEM18
ClinVarTMEM18
1000_GenomesTMEM18 
Exome Variant ServerTMEM18
ExAC (Exome Aggregation Consortium)ENSG00000151353
GNOMAD BrowserENSG00000151353
Genetic variants : HAPMAP129787
Genomic Variants (DGV)TMEM18 [DGVbeta]
DECIPHERTMEM18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM18 
Mutations
ICGC Data PortalTMEM18 
TCGA Data PortalTMEM18 
Broad Tumor PortalTMEM18
OASIS PortalTMEM18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM18
DgiDB (Drug Gene Interaction Database)TMEM18
DoCM (Curated mutations)TMEM18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM18 (select a term)
intoGenTMEM18
Cancer3DTMEM18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613220   
Orphanet
DisGeNETTMEM18
MedgenTMEM18
Genetic Testing Registry TMEM18
NextProtQ96B42 [Medical]
TSGene129787
GENETestsTMEM18
Target ValidationTMEM18
Huge Navigator TMEM18 [HugePedia]
snp3D : Map Gene to Disease129787
BioCentury BCIQTMEM18
ClinGenTMEM18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD129787
Chemical/Pharm GKB GenePA134873089
Clinical trialTMEM18
Miscellaneous
canSAR (ICR)TMEM18 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM18
EVEXTMEM18
GoPubMedTMEM18
iHOPTMEM18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:38:46 CET 2017

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