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TMEM181 (transmembrane protein 181)

Identity

Alias (NCBI)GPR178
KIAA1423
HGNC (Hugo) TMEM181
HGNC Previous nameKIAA1423
 GPR178
HGNC Previous nameG protein-coupled receptor 178
 KIAA1423
LocusID (NCBI) 57583
Atlas_Id 74844
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 158536640 and ends at 158635429 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL24A1 (1p22.3) / TMEM181 (6q25.3)GDI1 (Xq28) / TMEM181 (6q25.3)TMEM181 (6q25.3) / HMGCLL1 (6p12.1)
TMEM181 (6q25.3) / SMARCA2 (9p24.3)TMEM181 (6q25.3) / TMEM181 (6q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM181   20958
Cards
Entrez_Gene (NCBI)TMEM181    transmembrane protein 181
AliasesGPR178; KIAA1423
GeneCards (Weizmann)TMEM181
Ensembl hg19 (Hinxton)ENSG00000146433 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146433 [Gene_View]  ENSG00000146433 [Sequence]  chr6:158536640-158635429 [Contig_View]  TMEM181 [Vega]
ICGC DataPortalENSG00000146433
TCGA cBioPortalTMEM181
AceView (NCBI)TMEM181
Genatlas (Paris)TMEM181
SOURCE (Princeton)TMEM181
Genetics Home Reference (NIH)TMEM181
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM181  -     chr6:158536640-158635429 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM181  -     6q25.3   [Description]    (hg19-Feb_2009)
GoldenPathTMEM181 - 6q25.3 [CytoView hg19]  TMEM181 - 6q25.3 [CytoView hg38]
ImmunoBaseENSG00000146433
Genome Data Viewer NCBITMEM181 [Mapview hg19]  
OMIM613209   
Gene and transcription
Genbank (Entrez)AB037844 AJ420476 AJ420523 AK023059 AL359569
RefSeq transcript (Entrez)NM_001376817 NM_001376850 NM_001376852 NM_001376854 NM_001376855 NM_001376856 NM_020823
Consensus coding sequences : CCDS (NCBI)TMEM181
Gene ExpressionTMEM181 [ NCBI-GEO ]   TMEM181 [ EBI - ARRAY_EXPRESS ]   TMEM181 [ SEEK ]   TMEM181 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM181 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM181 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57583
GTEX Portal (Tissue expression)TMEM181
Human Protein AtlasENSG00000146433-TMEM181 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2C4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2C4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2C4
PhosPhoSitePlusQ9P2C4
Domains : Interpro (EBI)TMEM181   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM181
SuperfamilyQ9P2C4
AlphaFold pdb e-kbQ9P2C4   
Human Protein Atlas [tissue]ENSG00000146433-TMEM181 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9P2C4
IntAct (EBI)Q9P2C4
BioGRIDTMEM181
STRING (EMBL)TMEM181
ZODIACTMEM181
Ontologies - Pathways
QuickGOQ9P2C4
Ontology : AmiGOtoxic substance binding  toxic substance binding  integral component of membrane  
Ontology : EGO-EBItoxic substance binding  toxic substance binding  integral component of membrane  
NDEx NetworkTMEM181
Atlas of Cancer Signalling NetworkTMEM181
Wikipedia pathwaysTMEM181
Orthology - Evolution
OrthoDB57583
GeneTree (enSembl)ENSG00000146433
Phylogenetic Trees/Animal Genes : TreeFamTMEM181
Homologs : HomoloGeneTMEM181
Homology/Alignments : Family Browser (UCSC)TMEM181
Gene fusions - Rearrangements
Fusion : QuiverTMEM181
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM181 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM181
dbVarTMEM181
ClinVarTMEM181
MonarchTMEM181
1000_GenomesTMEM181 
Exome Variant ServerTMEM181
GNOMAD BrowserENSG00000146433
Varsome BrowserTMEM181
ACMGTMEM181 variants
VarityQ9P2C4
Genomic Variants (DGV)TMEM181 [DGVbeta]
DECIPHERTMEM181 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM181 
Mutations
ICGC Data PortalTMEM181 
TCGA Data PortalTMEM181 
Broad Tumor PortalTMEM181
OASIS PortalTMEM181 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM181  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM181
Mutations and Diseases : HGMDTMEM181
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM181
DgiDB (Drug Gene Interaction Database)TMEM181
DoCM (Curated mutations)TMEM181
CIViC (Clinical Interpretations of Variants in Cancer)TMEM181
Cancer3DTMEM181
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613209   
Orphanet
DisGeNETTMEM181
MedgenTMEM181
Genetic Testing Registry TMEM181
NextProtQ9P2C4 [Medical]
GENETestsTMEM181
Target ValidationTMEM181
Huge Navigator TMEM181 [HugePedia]
ClinGenTMEM181
Clinical trials, drugs, therapy
MyCancerGenomeTMEM181
Protein Interactions : CTDTMEM181
Pharm GKB GenePA162406036
PharosQ9P2C4
Clinical trialTMEM181
Miscellaneous
canSAR (ICR)TMEM181
HarmonizomeTMEM181
DataMed IndexTMEM181
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM181
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:25:55 CEST 2021

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