Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMEM181 (transmembrane protein 181)

Identity

Alias_namesKIAA1423
GPR178
G protein-coupled receptor 178
KIAA1423
Other alias
HGNC (Hugo) TMEM181
LocusID (NCBI) 57583
Atlas_Id 74844
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 158536436 and ends at 158635435 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL24A1 (1p22.3) / TMEM181 (6q25.3)GDI1 (Xq28) / TMEM181 (6q25.3)TMEM181 (6q25.3) / HMGCLL1 (6p12.1)
TMEM181 (6q25.3) / SMARCA2 (9p24.3)TMEM181 (6q25.3) / TMEM181 (6q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p12;q25) TMEM181/HMGCLL1


External links

Nomenclature
HGNC (Hugo)TMEM181   20958
Cards
Entrez_Gene (NCBI)TMEM181  57583  transmembrane protein 181
AliasesGPR178; KIAA1423
GeneCards (Weizmann)TMEM181
Ensembl hg19 (Hinxton)ENSG00000146433 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146433 [Gene_View]  ENSG00000146433 [Sequence]  chr6:158536436-158635435 [Contig_View]  TMEM181 [Vega]
ICGC DataPortalENSG00000146433
TCGA cBioPortalTMEM181
AceView (NCBI)TMEM181
Genatlas (Paris)TMEM181
WikiGenes57583
SOURCE (Princeton)TMEM181
Genetics Home Reference (NIH)TMEM181
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM181  -     chr6:158536436-158635435 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM181  -     6q25.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM181 - 6q25.3 [CytoView hg19]  TMEM181 - 6q25.3 [CytoView hg38]
Mapping of homologs : NCBITMEM181 [Mapview hg19]  TMEM181 [Mapview hg38]
OMIM613209   
Gene and transcription
Genbank (Entrez)AB037844 AJ420476 AJ420523 AK023059 AL359569
RefSeq transcript (Entrez)NM_020823
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM181
Cluster EST : UnigeneHs.666596 [ NCBI ]
CGAP (NCI)Hs.666596
Alternative Splicing GalleryENSG00000146433
Gene ExpressionTMEM181 [ NCBI-GEO ]   TMEM181 [ EBI - ARRAY_EXPRESS ]   TMEM181 [ SEEK ]   TMEM181 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM181 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57583
GTEX Portal (Tissue expression)TMEM181
Human Protein AtlasENSG00000146433-TMEM181 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2C4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2C4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2C4
Splice isoforms : SwissVarQ9P2C4
PhosPhoSitePlusQ9P2C4
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM181
DMDM Disease mutations57583
Blocks (Seattle)TMEM181
SuperfamilyQ9P2C4
Human Protein Atlas [tissue]ENSG00000146433-TMEM181 [tissue]
Peptide AtlasQ9P2C4
IPIIPI00856096   IPI00166790   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2C4
IntAct (EBI)Q9P2C4
FunCoupENSG00000146433
BioGRIDTMEM181
STRING (EMBL)TMEM181
ZODIACTMEM181
Ontologies - Pathways
QuickGOQ9P2C4
Ontology : AmiGOpathogenesis  toxic substance binding  integral component of membrane  
Ontology : EGO-EBIpathogenesis  toxic substance binding  integral component of membrane  
NDEx NetworkTMEM181
Atlas of Cancer Signalling NetworkTMEM181
Wikipedia pathwaysTMEM181
Orthology - Evolution
OrthoDB57583
GeneTree (enSembl)ENSG00000146433
Phylogenetic Trees/Animal Genes : TreeFamTMEM181
HOVERGENQ9P2C4
HOGENOMQ9P2C4
Homologs : HomoloGeneTMEM181
Homology/Alignments : Family Browser (UCSC)TMEM181
Gene fusions - Rearrangements
Fusion : QuiverTMEM181
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM181 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM181
dbVarTMEM181
ClinVarTMEM181
1000_GenomesTMEM181 
Exome Variant ServerTMEM181
ExAC (Exome Aggregation Consortium)ENSG00000146433
GNOMAD BrowserENSG00000146433
Varsome BrowserTMEM181
Genetic variants : HAPMAP57583
Genomic Variants (DGV)TMEM181 [DGVbeta]
DECIPHERTMEM181 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM181 
Mutations
ICGC Data PortalTMEM181 
TCGA Data PortalTMEM181 
Broad Tumor PortalTMEM181
OASIS PortalTMEM181 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM181  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM181
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM181
DgiDB (Drug Gene Interaction Database)TMEM181
DoCM (Curated mutations)TMEM181 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM181 (select a term)
intoGenTMEM181
Cancer3DTMEM181(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613209   
Orphanet
DisGeNETTMEM181
MedgenTMEM181
Genetic Testing Registry TMEM181
NextProtQ9P2C4 [Medical]
TSGene57583
GENETestsTMEM181
Target ValidationTMEM181
Huge Navigator TMEM181 [HugePedia]
snp3D : Map Gene to Disease57583
BioCentury BCIQTMEM181
ClinGenTMEM181
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57583
Chemical/Pharm GKB GenePA162406036
Clinical trialTMEM181
Miscellaneous
canSAR (ICR)TMEM181 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM181
EVEXTMEM181
GoPubMedTMEM181
iHOPTMEM181
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:35:24 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.