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TMEM189 (transmembrane protein 189)

Identity

Alias_symbol (synonym)Kua
Other aliasKUA
HGNC (Hugo) TMEM189
LocusID (NCBI) 387521
Atlas_Id 74854
Location 20q13.13  [Link to chromosome band 20q13]
Location_base_pair Starts at 48740274 and ends at 48770335 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMEM189 (20q13.13) / UBE2V1 (20q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM189   16735
Cards
Entrez_Gene (NCBI)TMEM189  387521  transmembrane protein 189
AliasesKUA
GeneCards (Weizmann)TMEM189
Ensembl hg19 (Hinxton)ENSG00000240849 [Gene_View]  chr20:48740274-48770335 [Contig_View]  TMEM189 [Vega]
Ensembl hg38 (Hinxton)ENSG00000240849 [Gene_View]  chr20:48740274-48770335 [Contig_View]  TMEM189 [Vega]
ICGC DataPortalENSG00000240849
TCGA cBioPortalTMEM189
AceView (NCBI)TMEM189
Genatlas (Paris)TMEM189
WikiGenes387521
SOURCE (Princeton)TMEM189
Genetics Home Reference (NIH)TMEM189
Genomic and cartography
GoldenPath hg19 (UCSC)TMEM189  -     chr20:48740274-48770335 -  20q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMEM189  -     20q13.13   [Description]    (hg38-Dec_2013)
EnsemblTMEM189 - 20q13.13 [CytoView hg19]  TMEM189 - 20q13.13 [CytoView hg38]
Mapping of homologs : NCBITMEM189 [Mapview hg19]  TMEM189 [Mapview hg38]
OMIM610994   
Gene and transcription
Genbank (Entrez)AB044550 AF155120 AK023028 AK304595 BC018893
RefSeq transcript (Entrez)NM_001162505 NM_199129
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)TMEM189
Cluster EST : UnigeneHs.744839 [ NCBI ]
CGAP (NCI)Hs.744839
Alternative Splicing GalleryENSG00000240849
Gene ExpressionTMEM189 [ NCBI-GEO ]   TMEM189 [ EBI - ARRAY_EXPRESS ]   TMEM189 [ SEEK ]   TMEM189 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM189 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)387521
GTEX Portal (Tissue expression)TMEM189
Protein : pattern, domain, 3D structure
UniProt/SwissProtA5PLL7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA5PLL7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA5PLL7
Splice isoforms : SwissVarA5PLL7
PhosPhoSitePlusA5PLL7
Domains : Interpro (EBI)Kua   
Domain families : Pfam (Sanger)Kua-UEV1_localn (PF10520)   
Domain families : Pfam (NCBI)pfam10520   
Conserved Domain (NCBI)TMEM189
DMDM Disease mutations387521
Blocks (Seattle)TMEM189
SuperfamilyA5PLL7
Human Protein AtlasENSG00000240849
Peptide AtlasA5PLL7
HPRD17257
IPIIPI00454991   IPI00447356   IPI00472498   IPI00007847   IPI00030962   IPI00872898   IPI00019599   IPI00607872   IPI00945783   IPI00514724   IPI00916301   IPI00917332   IPI00965965   
Protein Interaction databases
DIP (DOE-UCLA)A5PLL7
IntAct (EBI)A5PLL7
FunCoupENSG00000240849
BioGRIDTMEM189
STRING (EMBL)TMEM189
ZODIACTMEM189
Ontologies - Pathways
QuickGOA5PLL7
Ontology : AmiGOcytoplasm  endoplasmic reticulum membrane  integral component of membrane  protein ubiquitination  ubiquitin protein ligase binding  ubiquitin protein ligase activity  
Ontology : EGO-EBIcytoplasm  endoplasmic reticulum membrane  integral component of membrane  protein ubiquitination  ubiquitin protein ligase binding  ubiquitin protein ligase activity  
NDEx NetworkTMEM189
Atlas of Cancer Signalling NetworkTMEM189
Wikipedia pathwaysTMEM189
Orthology - Evolution
OrthoDB387521
GeneTree (enSembl)ENSG00000240849
Phylogenetic Trees/Animal Genes : TreeFamTMEM189
HOVERGENA5PLL7
HOGENOMA5PLL7
Homologs : HomoloGeneTMEM189
Homology/Alignments : Family Browser (UCSC)TMEM189
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM189 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM189
dbVarTMEM189
ClinVarTMEM189
1000_GenomesTMEM189 
Exome Variant ServerTMEM189
ExAC (Exome Aggregation Consortium)TMEM189 (select the gene name)
Genetic variants : HAPMAP387521
Genomic Variants (DGV)TMEM189 [DGVbeta]
DECIPHER (Syndromes)20:48740274-48770335  ENSG00000240849
CONAN: Copy Number AnalysisTMEM189 
Mutations
ICGC Data PortalTMEM189 
TCGA Data PortalTMEM189 
Broad Tumor PortalTMEM189
OASIS PortalTMEM189 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM189  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM189
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM189
DgiDB (Drug Gene Interaction Database)TMEM189
DoCM (Curated mutations)TMEM189 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM189 (select a term)
intoGenTMEM189
Cancer3DTMEM189(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610994   
Orphanet
MedgenTMEM189
Genetic Testing Registry TMEM189
NextProtA5PLL7 [Medical]
TSGene387521
GENETestsTMEM189
Huge Navigator TMEM189 [HugePedia]
snp3D : Map Gene to Disease387521
BioCentury BCIQTMEM189
ClinGenTMEM189
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD387521
Chemical/Pharm GKB GenePA162406209
Clinical trialTMEM189
Miscellaneous
canSAR (ICR)TMEM189 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM189
EVEXTMEM189
GoPubMedTMEM189
iHOPTMEM189
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:48:38 CET 2017

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