Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMEM199 (transmembrane protein 199)

Identity

Alias (NCBI)C17orf32
CDG2P
VMA12
VPH2
HGNC (Hugo) TMEM199
HGNC Alias symbMGC45714
VPH2
VMA12
HGNC Previous nameC17orf32
HGNC Previous namechromosome 17 open reading frame 32
LocusID (NCBI) 147007
Atlas_Id 74865
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 28357647 and ends at 28363683 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM199 (17q11.2) / TFIP11 (22q12.1)TMEM199 (17q11.2) / TMEM199 (17q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM199   18085
Cards
Entrez_Gene (NCBI)TMEM199    transmembrane protein 199
AliasesC17orf32; CDG2P; VMA12; VPH2
GeneCards (Weizmann)TMEM199
Ensembl hg19 (Hinxton)ENSG00000244045 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244045 [Gene_View]  ENSG00000244045 [Sequence]  chr17:28357647-28363683 [Contig_View]  TMEM199 [Vega]
ICGC DataPortalENSG00000244045
TCGA cBioPortalTMEM199
AceView (NCBI)TMEM199
Genatlas (Paris)TMEM199
SOURCE (Princeton)TMEM199
Genetics Home Reference (NIH)TMEM199
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM199  -     chr17:28357647-28363683 +  17q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM199  -     17q11.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM199 - 17q11.2 [CytoView hg19]  TMEM199 - 17q11.2 [CytoView hg38]
ImmunoBaseENSG00000244045
Genome Data Viewer NCBITMEM199 [Mapview hg19]  
OMIM616815   616829   
Gene and transcription
Genbank (Entrez)AA279827 AK223584 AK291475 AK311363 AY074907
RefSeq transcript (Entrez)NM_152464
Consensus coding sequences : CCDS (NCBI)TMEM199
Gene ExpressionTMEM199 [ NCBI-GEO ]   TMEM199 [ EBI - ARRAY_EXPRESS ]   TMEM199 [ SEEK ]   TMEM199 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM199 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM199 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)147007
GTEX Portal (Tissue expression)TMEM199
Human Protein AtlasENSG00000244045-TMEM199 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N511   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N511  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N511
PhosPhoSitePlusQ8N511
Domains : Interpro (EBI)ATPase_Vma12   
Domain families : Pfam (Sanger)Vma12 (PF11712)   
Domain families : Pfam (NCBI)pfam11712   
Conserved Domain (NCBI)TMEM199
SuperfamilyQ8N511
AlphaFold pdb e-kbQ8N511   
Human Protein Atlas [tissue]ENSG00000244045-TMEM199 [tissue]
HPRD12679
Protein Interaction databases
DIP (DOE-UCLA)Q8N511
IntAct (EBI)Q8N511
BioGRIDTMEM199
STRING (EMBL)TMEM199
ZODIACTMEM199
Ontologies - Pathways
QuickGOQ8N511
Ontology : AmiGOprotein binding  lysosome  endoplasmic reticulum  endoplasmic reticulum membrane  cellular iron ion homeostasis  lysosomal lumen acidification  endomembrane system  integral component of membrane  vacuolar proton-transporting V-type ATPase complex  COPI-coated vesicle membrane  endoplasmic reticulum-Golgi intermediate compartment membrane  cellular response to increased oxygen levels  vacuolar proton-transporting V-type ATPase complex assembly  lysosomal protein catabolic process  
Ontology : EGO-EBIprotein binding  lysosome  endoplasmic reticulum  endoplasmic reticulum membrane  cellular iron ion homeostasis  lysosomal lumen acidification  endomembrane system  integral component of membrane  vacuolar proton-transporting V-type ATPase complex  COPI-coated vesicle membrane  endoplasmic reticulum-Golgi intermediate compartment membrane  cellular response to increased oxygen levels  vacuolar proton-transporting V-type ATPase complex assembly  lysosomal protein catabolic process  
NDEx NetworkTMEM199
Atlas of Cancer Signalling NetworkTMEM199
Wikipedia pathwaysTMEM199
Orthology - Evolution
OrthoDB147007
GeneTree (enSembl)ENSG00000244045
Phylogenetic Trees/Animal Genes : TreeFamTMEM199
Homologs : HomoloGeneTMEM199
Homology/Alignments : Family Browser (UCSC)TMEM199
Gene fusions - Rearrangements
Fusion : QuiverTMEM199
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM199 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM199
dbVarTMEM199
ClinVarTMEM199
MonarchTMEM199
1000_GenomesTMEM199 
Exome Variant ServerTMEM199
GNOMAD BrowserENSG00000244045
Varsome BrowserTMEM199
ACMGTMEM199 variants
VarityQ8N511
Genomic Variants (DGV)TMEM199 [DGVbeta]
DECIPHERTMEM199 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM199 
Mutations
ICGC Data PortalTMEM199 
TCGA Data PortalTMEM199 
Broad Tumor PortalTMEM199
OASIS PortalTMEM199 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM199  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM199
Mutations and Diseases : HGMDTMEM199
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM199
DgiDB (Drug Gene Interaction Database)TMEM199
DoCM (Curated mutations)TMEM199
CIViC (Clinical Interpretations of Variants in Cancer)TMEM199
Cancer3DTMEM199
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616815    616829   
Orphanet
DisGeNETTMEM199
MedgenTMEM199
Genetic Testing Registry TMEM199
NextProtQ8N511 [Medical]
GENETestsTMEM199
Target ValidationTMEM199
Huge Navigator TMEM199 [HugePedia]
ClinGenTMEM199
Clinical trials, drugs, therapy
MyCancerGenomeTMEM199
Protein Interactions : CTDTMEM199
Pharm GKB GenePA162406348
PharosQ8N511
Clinical trialTMEM199
Miscellaneous
canSAR (ICR)TMEM199
HarmonizomeTMEM199
DataMed IndexTMEM199
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM199
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:25:58 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.