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TMEM2 (transmembrane protein 2)

Identity

Other alias-
HGNC (Hugo) TMEM2
LocusID (NCBI) 23670
Atlas_Id 74866
Location 9q21.13  [Link to chromosome band 9q21]
Location_base_pair Starts at 71683366 and ends at 71768884 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPARD (6p21.31) / TMEM2 (9q21.13)TANC1 (2q24.2) / TMEM2 (9q21.13)TMEM2 (9q21.13) / BHLHE40 (3p26.1)
TMEM2 (9q21.13) / NRDC (1p32.3)TMEM2 (9q21.13) / TMEM2 (9q21.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM2   11869
Cards
Entrez_Gene (NCBI)TMEM2  23670  transmembrane protein 2
Aliases
GeneCards (Weizmann)TMEM2
Ensembl hg19 (Hinxton)ENSG00000135048 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135048 [Gene_View]  chr9:71683366-71768884 [Contig_View]  TMEM2 [Vega]
ICGC DataPortalENSG00000135048
TCGA cBioPortalTMEM2
AceView (NCBI)TMEM2
Genatlas (Paris)TMEM2
WikiGenes23670
SOURCE (Princeton)TMEM2
Genetics Home Reference (NIH)TMEM2
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM2  -     chr9:71683366-71768884 -  9q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM2  -     9q21.13   [Description]    (hg19-Feb_2009)
EnsemblTMEM2 - 9q21.13 [CytoView hg19]  TMEM2 - 9q21.13 [CytoView hg38]
Mapping of homologs : NCBITMEM2 [Mapview hg19]  TMEM2 [Mapview hg38]
OMIM605835   
Gene and transcription
Genbank (Entrez)AB037833 AF137030 AK027818 AK075370 AK300405
RefSeq transcript (Entrez)NM_001135820 NM_001349784 NM_013390
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM2
Cluster EST : UnigeneHs.494146 [ NCBI ]
CGAP (NCI)Hs.494146
Alternative Splicing GalleryENSG00000135048
Gene ExpressionTMEM2 [ NCBI-GEO ]   TMEM2 [ EBI - ARRAY_EXPRESS ]   TMEM2 [ SEEK ]   TMEM2 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23670
GTEX Portal (Tissue expression)TMEM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHN6
Splice isoforms : SwissVarQ9UHN6
PhosPhoSitePlusQ9UHN6
Domaine pattern : Prosite (Expaxy)G8 (PS51484)   
Domains : Interpro (EBI)G8_domain    Pectin_lyase_fold/virulence   
Domain families : Pfam (Sanger)G8 (PF10162)   
Domain families : Pfam (NCBI)pfam10162   
Domain families : Smart (EMBL)G8 (SM01225)  
Conserved Domain (NCBI)TMEM2
DMDM Disease mutations23670
Blocks (Seattle)TMEM2
SuperfamilyQ9UHN6
Human Protein AtlasENSG00000135048
Peptide AtlasQ9UHN6
HPRD09317
IPIIPI00170706   IPI01011640   IPI00911057   IPI00513764   IPI00513851   IPI00644795   IPI01022732   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHN6
IntAct (EBI)Q9UHN6
FunCoupENSG00000135048
BioGRIDTMEM2
STRING (EMBL)TMEM2
ZODIACTMEM2
Ontologies - Pathways
QuickGOQ9UHN6
Ontology : AmiGOmulticellular organism development  integral component of membrane  cadherin binding  extracellular exosome  
Ontology : EGO-EBImulticellular organism development  integral component of membrane  cadherin binding  extracellular exosome  
NDEx NetworkTMEM2
Atlas of Cancer Signalling NetworkTMEM2
Wikipedia pathwaysTMEM2
Orthology - Evolution
OrthoDB23670
GeneTree (enSembl)ENSG00000135048
Phylogenetic Trees/Animal Genes : TreeFamTMEM2
HOVERGENQ9UHN6
HOGENOMQ9UHN6
Homologs : HomoloGeneTMEM2
Homology/Alignments : Family Browser (UCSC)TMEM2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM2
dbVarTMEM2
ClinVarTMEM2
1000_GenomesTMEM2 
Exome Variant ServerTMEM2
ExAC (Exome Aggregation Consortium)TMEM2 (select the gene name)
Genetic variants : HAPMAP23670
Genomic Variants (DGV)TMEM2 [DGVbeta]
DECIPHERTMEM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM2 
Mutations
ICGC Data PortalTMEM2 
TCGA Data PortalTMEM2 
Broad Tumor PortalTMEM2
OASIS PortalTMEM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM2
DgiDB (Drug Gene Interaction Database)TMEM2
DoCM (Curated mutations)TMEM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM2 (select a term)
intoGenTMEM2
Cancer3DTMEM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605835   
Orphanet
MedgenTMEM2
Genetic Testing Registry TMEM2
NextProtQ9UHN6 [Medical]
TSGene23670
GENETestsTMEM2
Target ValidationTMEM2
Huge Navigator TMEM2 [HugePedia]
snp3D : Map Gene to Disease23670
BioCentury BCIQTMEM2
ClinGenTMEM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23670
Chemical/Pharm GKB GenePA36570
Clinical trialTMEM2
Miscellaneous
canSAR (ICR)TMEM2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM2
EVEXTMEM2
GoPubMedTMEM2
iHOPTMEM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:46:05 CEST 2017

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