Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMEM217 (transmembrane protein 217)

Identity

Alias_namesC6orf128
chromosome 6 open reading frame 128
Alias_symbol (synonym)dJ355M6.2
Other alias
HGNC (Hugo) TMEM217
LocusID (NCBI) 221468
Atlas_Id 74883
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 37217642 and ends at 37258155 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAH8 (6p21.2) / TMEM217 (6p21.2)LRP8 (1p32.3) / TMEM217 (6p21.2)LRP8 TMEM217
DNAH8 TMEM217

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;6)(p32;p21) LRP8/TMEM217
t(6;6)(p21;p21) DNAH8/TMEM217


External links

Nomenclature
HGNC (Hugo)TMEM217   21238
Cards
Entrez_Gene (NCBI)TMEM217  221468  transmembrane protein 217
AliasesC6orf128; dJ355M6.2
GeneCards (Weizmann)TMEM217
Ensembl hg19 (Hinxton)ENSG00000172738 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172738 [Gene_View]  ENSG00000172738 [Sequence]  chr6:37217642-37258155 [Contig_View]  TMEM217 [Vega]
ICGC DataPortalENSG00000172738
TCGA cBioPortalTMEM217
AceView (NCBI)TMEM217
Genatlas (Paris)TMEM217
WikiGenes221468
SOURCE (Princeton)TMEM217
Genetics Home Reference (NIH)TMEM217
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM217  -     chr6:37217642-37258155 -  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM217  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblTMEM217 - 6p21.2 [CytoView hg19]  TMEM217 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBITMEM217 [Mapview hg19]  TMEM217 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK098666 AW137001 AW188099 BC009625 BC026012
RefSeq transcript (Entrez)NM_001162900 NM_001286401 NM_145316
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM217
Cluster EST : UnigeneHs.520101 [ NCBI ]
CGAP (NCI)Hs.520101
Alternative Splicing GalleryENSG00000172738
Gene ExpressionTMEM217 [ NCBI-GEO ]   TMEM217 [ EBI - ARRAY_EXPRESS ]   TMEM217 [ SEEK ]   TMEM217 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM217 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221468
GTEX Portal (Tissue expression)TMEM217
Human Protein AtlasENSG00000172738-TMEM217 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N7C4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N7C4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N7C4
Splice isoforms : SwissVarQ8N7C4
PhosPhoSitePlusQ8N7C4
Domains : Interpro (EBI)DUF4534   
Domain families : Pfam (Sanger)DUF4534 (PF15049)   
Domain families : Pfam (NCBI)pfam15049   
Conserved Domain (NCBI)TMEM217
DMDM Disease mutations221468
Blocks (Seattle)TMEM217
SuperfamilyQ8N7C4
Human Protein Atlas [tissue]ENSG00000172738-TMEM217 [tissue]
Peptide AtlasQ8N7C4
HPRD12848
IPIIPI00171170   IPI00180373   IPI00166070   
Protein Interaction databases
DIP (DOE-UCLA)Q8N7C4
IntAct (EBI)Q8N7C4
FunCoupENSG00000172738
BioGRIDTMEM217
STRING (EMBL)TMEM217
ZODIACTMEM217
Ontologies - Pathways
QuickGOQ8N7C4
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM217
Atlas of Cancer Signalling NetworkTMEM217
Wikipedia pathwaysTMEM217
Orthology - Evolution
OrthoDB221468
GeneTree (enSembl)ENSG00000172738
Phylogenetic Trees/Animal Genes : TreeFamTMEM217
HOVERGENQ8N7C4
HOGENOMQ8N7C4
Homologs : HomoloGeneTMEM217
Homology/Alignments : Family Browser (UCSC)TMEM217
Gene fusions - Rearrangements
Fusion PortalLRP8 TMEM217
Fusion PortalDNAH8 TMEM217
Fusion : QuiverTMEM217
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM217 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM217
dbVarTMEM217
ClinVarTMEM217
1000_GenomesTMEM217 
Exome Variant ServerTMEM217
ExAC (Exome Aggregation Consortium)ENSG00000172738
GNOMAD BrowserENSG00000172738
Varsome BrowserTMEM217
Genetic variants : HAPMAP221468
Genomic Variants (DGV)TMEM217 [DGVbeta]
DECIPHERTMEM217 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM217 
Mutations
ICGC Data PortalTMEM217 
TCGA Data PortalTMEM217 
Broad Tumor PortalTMEM217
OASIS PortalTMEM217 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM217  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM217
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM217
DgiDB (Drug Gene Interaction Database)TMEM217
DoCM (Curated mutations)TMEM217 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM217 (select a term)
intoGenTMEM217
Cancer3DTMEM217(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM217
MedgenTMEM217
Genetic Testing Registry TMEM217
NextProtQ8N7C4 [Medical]
TSGene221468
GENETestsTMEM217
Target ValidationTMEM217
Huge Navigator TMEM217 [HugePedia]
snp3D : Map Gene to Disease221468
BioCentury BCIQTMEM217
ClinGenTMEM217
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221468
Chemical/Pharm GKB GenePA162406568
Clinical trialTMEM217
Miscellaneous
canSAR (ICR)TMEM217 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM217
EVEXTMEM217
GoPubMedTMEM217
iHOPTMEM217
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:35:32 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.