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TMEM245 (transmembrane protein 245)

Identity

Alias (NCBI)C9orf5
CG-2
CG2
HGNC (Hugo) TMEM245
HGNC Alias symbCG-2
HGNC Previous nameC9orf5
HGNC Previous namechromosome 9 open reading frame 5
LocusID (NCBI) 23731
Atlas_Id 74908
Location 9q31.3  [Link to chromosome band 9q31]
Location_base_pair Starts at 109015135 and ends at 109119947 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PDIA3P1 (1q21.1) / TMEM245 (9q31.3)TMEM245 (9q31.3) / FKBP15 (9q32)TMEM245 (9q31.3) / FRRS1L (9q31.3)
TMEM245 (9q31.3) / GOLM1 (9q21.33)TMEM245 (9q31.3) / KMT2C (7q36.1)TMEM245 (9q31.3) / TMEM245 (9q31.3)
TRPC4AP (20q11.22) / TMEM245 (9q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(8;9)(q24;q31) NRBP2/TMEM245
t(8;9)(q24;q31) NRBP2/TMEM245


External links

 

Nomenclature
HGNC (Hugo)TMEM245   1363
Cards
Entrez_Gene (NCBI)TMEM245    transmembrane protein 245
AliasesC9orf5; CG-2; CG2
GeneCards (Weizmann)TMEM245
Ensembl hg19 (Hinxton)ENSG00000106771 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106771 [Gene_View]  ENSG00000106771 [Sequence]  chr9:109015135-109119947 [Contig_View]  TMEM245 [Vega]
ICGC DataPortalENSG00000106771
TCGA cBioPortalTMEM245
AceView (NCBI)TMEM245
Genatlas (Paris)TMEM245
SOURCE (Princeton)TMEM245
Genetics Home Reference (NIH)TMEM245
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM245  -     chr9:109015135-109119947 -  9q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM245  -     9q31.3   [Description]    (hg19-Feb_2009)
GoldenPathTMEM245 - 9q31.3 [CytoView hg19]  TMEM245 - 9q31.3 [CytoView hg38]
ImmunoBaseENSG00000106771
Genome Data Viewer NCBITMEM245 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA465408 AF086175 AF153415 AK074248 AK090543
RefSeq transcript (Entrez)NM_001099734 NM_032012
Consensus coding sequences : CCDS (NCBI)TMEM245
Gene ExpressionTMEM245 [ NCBI-GEO ]   TMEM245 [ EBI - ARRAY_EXPRESS ]   TMEM245 [ SEEK ]   TMEM245 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM245 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM245 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23731
GTEX Portal (Tissue expression)TMEM245
Human Protein AtlasENSG00000106771-TMEM245 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H330   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H330  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H330
PhosPhoSitePlusQ9H330
Domains : Interpro (EBI)AI-2E-like   
Domain families : Pfam (Sanger)AI-2E_transport (PF01594)   
Domain families : Pfam (NCBI)pfam01594   
Conserved Domain (NCBI)TMEM245
SuperfamilyQ9H330
AlphaFold pdb e-kbQ9H330   
Human Protein Atlas [tissue]ENSG00000106771-TMEM245 [tissue]
HPRD09866
Protein Interaction databases
DIP (DOE-UCLA)Q9H330
IntAct (EBI)Q9H330
BioGRIDTMEM245
STRING (EMBL)TMEM245
ZODIACTMEM245
Ontologies - Pathways
QuickGOQ9H330
Ontology : AmiGOmolecular_function  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  biological_process  integral component of membrane  
NDEx NetworkTMEM245
Atlas of Cancer Signalling NetworkTMEM245
Wikipedia pathwaysTMEM245
Orthology - Evolution
OrthoDB23731
GeneTree (enSembl)ENSG00000106771
Phylogenetic Trees/Animal Genes : TreeFamTMEM245
Homologs : HomoloGeneTMEM245
Homology/Alignments : Family Browser (UCSC)TMEM245
Gene fusions - Rearrangements
Fusion : QuiverTMEM245
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM245 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM245
dbVarTMEM245
ClinVarTMEM245
MonarchTMEM245
1000_GenomesTMEM245 
Exome Variant ServerTMEM245
GNOMAD BrowserENSG00000106771
Varsome BrowserTMEM245
ACMGTMEM245 variants
VarityQ9H330
Genomic Variants (DGV)TMEM245 [DGVbeta]
DECIPHERTMEM245 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM245 
Mutations
ICGC Data PortalTMEM245 
TCGA Data PortalTMEM245 
Broad Tumor PortalTMEM245
OASIS PortalTMEM245 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM245  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM245
Mutations and Diseases : HGMDTMEM245
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM245
DgiDB (Drug Gene Interaction Database)TMEM245
DoCM (Curated mutations)TMEM245
CIViC (Clinical Interpretations of Variants in Cancer)TMEM245
Cancer3DTMEM245
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM245
MedgenTMEM245
Genetic Testing Registry TMEM245
NextProtQ9H330 [Medical]
GENETestsTMEM245
Target ValidationTMEM245
Huge Navigator TMEM245 [HugePedia]
ClinGenTMEM245
Clinical trials, drugs, therapy
MyCancerGenomeTMEM245
Protein Interactions : CTDTMEM245
Pharm GKB GenePA25980
PharosQ9H330
Clinical trialTMEM245
Miscellaneous
canSAR (ICR)TMEM245
HarmonizomeTMEM245
DataMed IndexTMEM245
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM245
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:26:06 CEST 2021

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