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TMEM38B (transmembrane protein 38B)

Identity

Alias (NCBI)C9orf87
D4Ertd89e
OI14
TRIC-B
TRICB
bA219P18.1
HGNC (Hugo) TMEM38B
HGNC Alias symbFLJ10493
bA219P18.1
D4Ertd89e
TRIC-B
HGNC Previous nameC9orf87
HGNC Previous namechromosome 9 open reading frame 87
LocusID (NCBI) 55151
Atlas_Id 74938
Location 9q31.2  [Link to chromosome band 9q31]
Location_base_pair Starts at 105694525 and ends at 105776611 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TJP2 (9q21.11) / TMEM38B (9q31.2)TMEM38B (9q31.2) / FKTN (9q31.2)TMEM38B (9q31.2) / PPP4R3B (2p16.1)
TMEM38B (9q31.2) / VAPA (18p11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;9)(q21;q31) TJP2/TMEM38B

External links

Nomenclature
HGNC (Hugo)TMEM38B   25535
Cards
Entrez_Gene (NCBI)TMEM38B    transmembrane protein 38B
AliasesC9orf87; D4Ertd89e; OI14; TRIC-B; 
TRICB; bA219P18.1
GeneCards (Weizmann)TMEM38B
Ensembl hg19 (Hinxton)ENSG00000095209 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095209 [Gene_View]  ENSG00000095209 [Sequence]  chr9:105694525-105776611 [Contig_View]  TMEM38B [Vega]
ICGC DataPortalENSG00000095209
TCGA cBioPortalTMEM38B
AceView (NCBI)TMEM38B
Genatlas (Paris)TMEM38B
SOURCE (Princeton)TMEM38B
Genetics Home Reference (NIH)TMEM38B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM38B  -     chr9:105694525-105776611 +  9q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM38B  -     9q31.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM38B - 9q31.2 [CytoView hg19]  TMEM38B - 9q31.2 [CytoView hg38]
ImmunoBaseENSG00000095209
genome Data Viewer NCBITMEM38B [Mapview hg19]  
OMIM611236   615066   
Gene and transcription
Genbank (Entrez)AK001355 AK309686 BC000049 BC031938 BU728078
RefSeq transcript (Entrez)NM_018112
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM38B
Alternative Splicing GalleryENSG00000095209
Gene ExpressionTMEM38B [ NCBI-GEO ]   TMEM38B [ EBI - ARRAY_EXPRESS ]   TMEM38B [ SEEK ]   TMEM38B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM38B [ Firebrowse - Broad ]
GenevisibleExpression of TMEM38B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55151
GTEX Portal (Tissue expression)TMEM38B
Human Protein AtlasENSG00000095209-TMEM38B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVV0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVV0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVV0
Splice isoforms : SwissVarQ9NVV0
PhosPhoSitePlusQ9NVV0
Domains : Interpro (EBI)TRIC_channel   
Domain families : Pfam (Sanger)TRIC (PF05197)   
Domain families : Pfam (NCBI)pfam05197   
Conserved Domain (NCBI)TMEM38B
Blocks (Seattle)TMEM38B
SuperfamilyQ9NVV0
Human Protein Atlas [tissue]ENSG00000095209-TMEM38B [tissue]
Peptide AtlasQ9NVV0
HPRD15538
IPIIPI00018237   IPI00646919   IPI00647451   IPI00641619   IPI00642155   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVV0
IntAct (EBI)Q9NVV0
BioGRIDTMEM38B
STRING (EMBL)TMEM38B
ZODIACTMEM38B
Ontologies - Pathways
QuickGOQ9NVV0
Ontology : AmiGOpotassium channel activity  cell  nucleus  endoplasmic reticulum organization  phospholipid biosynthetic process  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  integral component of membrane  bone mineralization  nuclear membrane  sarcoplasmic reticulum membrane  lung alveolus development  bone development  lung epithelial cell differentiation  secretion by lung epithelial cell involved in lung growth  extracellular matrix constituent secretion  cellular response to caffeine  potassium ion transmembrane transport  
Ontology : EGO-EBIpotassium channel activity  cell  nucleus  endoplasmic reticulum organization  phospholipid biosynthetic process  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  integral component of membrane  bone mineralization  nuclear membrane  sarcoplasmic reticulum membrane  lung alveolus development  bone development  lung epithelial cell differentiation  secretion by lung epithelial cell involved in lung growth  extracellular matrix constituent secretion  cellular response to caffeine  potassium ion transmembrane transport  
NDEx NetworkTMEM38B
Atlas of Cancer Signalling NetworkTMEM38B
Wikipedia pathwaysTMEM38B
Orthology - Evolution
OrthoDB55151
GeneTree (enSembl)ENSG00000095209
Phylogenetic Trees/Animal Genes : TreeFamTMEM38B
HOGENOMQ9NVV0
Homologs : HomoloGeneTMEM38B
Homology/Alignments : Family Browser (UCSC)TMEM38B
Gene fusions - Rearrangements
Fusion : QuiverTMEM38B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM38B [hg38]
dbVarTMEM38B
ClinVarTMEM38B
MonarchTMEM38B
1000_GenomesTMEM38B 
Exome Variant ServerTMEM38B
GNOMAD BrowserENSG00000095209
Varsome BrowserTMEM38B
Genomic Variants (DGV)TMEM38B [DGVbeta]
DECIPHERTMEM38B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM38B 
Mutations
ICGC Data PortalTMEM38B 
TCGA Data PortalTMEM38B 
Broad Tumor PortalTMEM38B
OASIS PortalTMEM38B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM38B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM38B
Mutations and Diseases : HGMDTMEM38B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Osteogenesis Imperfecta Variant Database
BioMutasearch TMEM38B
DgiDB (Drug Gene Interaction Database)TMEM38B
DoCM (Curated mutations)TMEM38B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM38B (select a term)
intoGenTMEM38B
Cancer3DTMEM38B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611236    615066   
Orphanet18794   
DisGeNETTMEM38B
MedgenTMEM38B
Genetic Testing Registry TMEM38B
NextProtQ9NVV0 [Medical]
GENETestsTMEM38B
Target ValidationTMEM38B
Huge Navigator TMEM38B [HugePedia]
ClinGenTMEM38B
Clinical trials, drugs, therapy
MyCancerGenomeTMEM38B
Protein Interactions : CTD
Pharm GKB GenePA134916126
Clinical trialTMEM38B
Miscellaneous
canSAR (ICR)TMEM38B (select the gene name)
HarmonizomeTMEM38B
DataMed IndexTMEM38B
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM38B
EVEXTMEM38B
GoPubMedTMEM38B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:32:28 CET 2020
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