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TMEM40 (transmembrane protein 40)

Identity

Alias (NCBI)-
HGNC (Hugo) TMEM40
HGNC Alias symbFLJ11036
LocusID (NCBI) 55287
Atlas_Id 57828
Location 3p25.2  [Link to chromosome band 3p25]
Location_base_pair Starts at 12733528 and ends at 12759259 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KRI1 (19p13.2) / TMEM40 (3p25.2)RAF1 (3p25.2) / TMEM40 (3p25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(3;3)(p25;p25) RAF1/TMEM40


External links

 

Nomenclature
HGNC (Hugo)TMEM40   25620
Cards
Entrez_Gene (NCBI)TMEM40    transmembrane protein 40
Aliases
GeneCards (Weizmann)TMEM40
Ensembl hg19 (Hinxton)ENSG00000088726 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000088726 [Gene_View]  ENSG00000088726 [Sequence]  chr3:12733528-12759259 [Contig_View]  TMEM40 [Vega]
ICGC DataPortalENSG00000088726
TCGA cBioPortalTMEM40
AceView (NCBI)TMEM40
Genatlas (Paris)TMEM40
SOURCE (Princeton)TMEM40
Genetics Home Reference (NIH)TMEM40
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM40  -     chr3:12733528-12759259 -  3p25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM40  -     3p25.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM40 - 3p25.2 [CytoView hg19]  TMEM40 - 3p25.2 [CytoView hg38]
ImmunoBaseENSG00000088726
Genome Data Viewer NCBITMEM40 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AI452552 AK001898 AK092470 AK301984 BC020658
RefSeq transcript (Entrez)NM_001284406 NM_001284407 NM_001284408 NM_018306
Consensus coding sequences : CCDS (NCBI)TMEM40
Gene ExpressionTMEM40 [ NCBI-GEO ]   TMEM40 [ EBI - ARRAY_EXPRESS ]   TMEM40 [ SEEK ]   TMEM40 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM40 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM40 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55287
GTEX Portal (Tissue expression)TMEM40
Human Protein AtlasENSG00000088726-TMEM40 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWA1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWA1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWA1
PhosPhoSitePlusQ8WWA1
Domains : Interpro (EBI)TMEM40   
Domain families : Pfam (Sanger)TMEM40 (PF15817)   
Domain families : Pfam (NCBI)pfam15817   
Conserved Domain (NCBI)TMEM40
SuperfamilyQ8WWA1
AlphaFold pdb e-kbQ8WWA1   
Human Protein Atlas [tissue]ENSG00000088726-TMEM40 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8WWA1
IntAct (EBI)Q8WWA1
BioGRIDTMEM40
STRING (EMBL)TMEM40
ZODIACTMEM40
Ontologies - Pathways
QuickGOQ8WWA1
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM40
Atlas of Cancer Signalling NetworkTMEM40
Wikipedia pathwaysTMEM40
Orthology - Evolution
OrthoDB55287
GeneTree (enSembl)ENSG00000088726
Phylogenetic Trees/Animal Genes : TreeFamTMEM40
Homologs : HomoloGeneTMEM40
Homology/Alignments : Family Browser (UCSC)TMEM40
Gene fusions - Rearrangements
Fusion : QuiverTMEM40
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM40 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM40
dbVarTMEM40
ClinVarTMEM40
MonarchTMEM40
1000_GenomesTMEM40 
Exome Variant ServerTMEM40
GNOMAD BrowserENSG00000088726
Varsome BrowserTMEM40
ACMGTMEM40 variants
VarityQ8WWA1
Genomic Variants (DGV)TMEM40 [DGVbeta]
DECIPHERTMEM40 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM40 
Mutations
ICGC Data PortalTMEM40 
TCGA Data PortalTMEM40 
Broad Tumor PortalTMEM40
OASIS PortalTMEM40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM40  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM40
Mutations and Diseases : HGMDTMEM40
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM40
DgiDB (Drug Gene Interaction Database)TMEM40
DoCM (Curated mutations)TMEM40
CIViC (Clinical Interpretations of Variants in Cancer)TMEM40
Cancer3DTMEM40
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM40
MedgenTMEM40
Genetic Testing Registry TMEM40
NextProtQ8WWA1 [Medical]
GENETestsTMEM40
Target ValidationTMEM40
Huge Navigator TMEM40 [HugePedia]
ClinGenTMEM40
Clinical trials, drugs, therapy
MyCancerGenomeTMEM40
Protein Interactions : CTDTMEM40
Pharm GKB GenePA134940002
PharosQ8WWA1
Clinical trialTMEM40
Miscellaneous
canSAR (ICR)TMEM40
HarmonizomeTMEM40
DataMed IndexTMEM40
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:35:31 CEST 2021

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