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TMEM64 (transmembrane protein 64)

Identity

Alias_symbol (synonym)DKFZp762C1112
Other alias-
HGNC (Hugo) TMEM64
LocusID (NCBI) 169200
Atlas_Id 74968
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 90621995 and ends at 90645905 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TMEM64 (8q21.3) / COPE (19p13.11)TMEM64 (8q21.3) / HHLA1 (8q24.22)TMEM64 (8q21.3) / OC90 (8q24.22)
TMEM64 (8q21.3) / TMEM64 (8q21.3)TMEM64 HHLA1TMEM64 OC90

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM64   25441
Cards
Entrez_Gene (NCBI)TMEM64  169200  transmembrane protein 64
Aliases
GeneCards (Weizmann)TMEM64
Ensembl hg19 (Hinxton)ENSG00000180694 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180694 [Gene_View]  chr8:90621995-90645905 [Contig_View]  TMEM64 [Vega]
ICGC DataPortalENSG00000180694
TCGA cBioPortalTMEM64
AceView (NCBI)TMEM64
Genatlas (Paris)TMEM64
WikiGenes169200
SOURCE (Princeton)TMEM64
Genetics Home Reference (NIH)TMEM64
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM64  -     chr8:90621995-90645905 -  8q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM64  -     8q21.3   [Description]    (hg19-Feb_2009)
EnsemblTMEM64 - 8q21.3 [CytoView hg19]  TMEM64 - 8q21.3 [CytoView hg38]
Mapping of homologs : NCBITMEM64 [Mapview hg19]  TMEM64 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA044031 AK095472 AK123958 AK300583 AL834364
RefSeq transcript (Entrez)NM_001008495 NM_001146273
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM64
Cluster EST : UnigeneHs.737401 [ NCBI ]
CGAP (NCI)Hs.737401
Alternative Splicing GalleryENSG00000180694
Gene ExpressionTMEM64 [ NCBI-GEO ]   TMEM64 [ EBI - ARRAY_EXPRESS ]   TMEM64 [ SEEK ]   TMEM64 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM64 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)169200
GTEX Portal (Tissue expression)TMEM64
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6YI46   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6YI46  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6YI46
Splice isoforms : SwissVarQ6YI46
PhosPhoSitePlusQ6YI46
Domains : Interpro (EBI)SNARE_assoc    TMEM64   
Domain families : Pfam (Sanger)SNARE_assoc (PF09335)   
Domain families : Pfam (NCBI)pfam09335   
Conserved Domain (NCBI)TMEM64
DMDM Disease mutations169200
Blocks (Seattle)TMEM64
SuperfamilyQ6YI46
Human Protein AtlasENSG00000180694
Peptide AtlasQ6YI46
HPRD16822
IPIIPI00784024   IPI00983859   IPI00909618   IPI00981455   
Protein Interaction databases
DIP (DOE-UCLA)Q6YI46
IntAct (EBI)Q6YI46
FunCoupENSG00000180694
BioGRIDTMEM64
STRING (EMBL)TMEM64
ZODIACTMEM64
Ontologies - Pathways
QuickGOQ6YI46
Ontology : AmiGOendoplasmic reticulum  integral component of membrane  regulation of ATPase activity  canonical Wnt signaling pathway involved in osteoblast differentiation  positive regulation of fat cell differentiation  negative regulation of osteoblast differentiation  positive regulation of osteoclast differentiation  positive regulation of bone resorption  regulation of cytosolic calcium ion concentration  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIendoplasmic reticulum  integral component of membrane  regulation of ATPase activity  canonical Wnt signaling pathway involved in osteoblast differentiation  positive regulation of fat cell differentiation  negative regulation of osteoblast differentiation  positive regulation of osteoclast differentiation  positive regulation of bone resorption  regulation of cytosolic calcium ion concentration  negative regulation of canonical Wnt signaling pathway  
NDEx NetworkTMEM64
Atlas of Cancer Signalling NetworkTMEM64
Wikipedia pathwaysTMEM64
Orthology - Evolution
OrthoDB169200
GeneTree (enSembl)ENSG00000180694
Phylogenetic Trees/Animal Genes : TreeFamTMEM64
HOVERGENQ6YI46
HOGENOMQ6YI46
Homologs : HomoloGeneTMEM64
Homology/Alignments : Family Browser (UCSC)TMEM64
Gene fusions - Rearrangements
Fusion: TCGATMEM64 HHLA1
Fusion: TCGATMEM64 OC90
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM64 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM64
dbVarTMEM64
ClinVarTMEM64
1000_GenomesTMEM64 
Exome Variant ServerTMEM64
ExAC (Exome Aggregation Consortium)TMEM64 (select the gene name)
Genetic variants : HAPMAP169200
Genomic Variants (DGV)TMEM64 [DGVbeta]
DECIPHERTMEM64 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM64 
Mutations
ICGC Data PortalTMEM64 
TCGA Data PortalTMEM64 
Broad Tumor PortalTMEM64
OASIS PortalTMEM64 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM64  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM64
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM64
DgiDB (Drug Gene Interaction Database)TMEM64
DoCM (Curated mutations)TMEM64 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM64 (select a term)
intoGenTMEM64
Cancer3DTMEM64(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMEM64
Genetic Testing Registry TMEM64
NextProtQ6YI46 [Medical]
TSGene169200
GENETestsTMEM64
Target ValidationTMEM64
Huge Navigator TMEM64 [HugePedia]
snp3D : Map Gene to Disease169200
BioCentury BCIQTMEM64
ClinGenTMEM64
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD169200
Chemical/Pharm GKB GenePA142670777
Clinical trialTMEM64
Miscellaneous
canSAR (ICR)TMEM64 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM64
EVEXTMEM64
GoPubMedTMEM64
iHOPTMEM64
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:42:04 CEST 2017

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