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TMEM74B (transmembrane protein 74B)

Identity

Alias_namesC20orf46
chromosome 20 open reading frame 46
Alias_symbol (synonym)FLJ11190
Other alias
HGNC (Hugo) TMEM74B
LocusID (NCBI) 55321
Atlas_Id 74976
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 1180561 and ends at 1184675 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM74B   15893
Cards
Entrez_Gene (NCBI)TMEM74B  55321  transmembrane protein 74B
AliasesC20orf46
GeneCards (Weizmann)TMEM74B
Ensembl hg19 (Hinxton)ENSG00000125895 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125895 [Gene_View]  chr20:1180561-1184675 [Contig_View]  TMEM74B [Vega]
ICGC DataPortalENSG00000125895
TCGA cBioPortalTMEM74B
AceView (NCBI)TMEM74B
Genatlas (Paris)TMEM74B
WikiGenes55321
SOURCE (Princeton)TMEM74B
Genetics Home Reference (NIH)TMEM74B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM74B  -     chr20:1180561-1184675 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM74B  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblTMEM74B - 20p13 [CytoView hg19]  TMEM74B - 20p13 [CytoView hg38]
Mapping of homologs : NCBITMEM74B [Mapview hg19]  TMEM74B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA861530 AK002052 AK126837 AW628999 BC156781
RefSeq transcript (Entrez)NM_001304748 NM_001304749 NM_018354
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM74B
Cluster EST : UnigeneHs.744640 [ NCBI ]
CGAP (NCI)Hs.744640
Alternative Splicing GalleryENSG00000125895
Gene ExpressionTMEM74B [ NCBI-GEO ]   TMEM74B [ EBI - ARRAY_EXPRESS ]   TMEM74B [ SEEK ]   TMEM74B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM74B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55321
GTEX Portal (Tissue expression)TMEM74B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NUR3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NUR3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NUR3
Splice isoforms : SwissVarQ9NUR3
PhosPhoSitePlusQ9NUR3
Domains : Interpro (EBI)TMEM74-like   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM74B
DMDM Disease mutations55321
Blocks (Seattle)TMEM74B
SuperfamilyQ9NUR3
Human Protein AtlasENSG00000125895
Peptide AtlasQ9NUR3
HPRD12772
IPIIPI00019964   IPI00641222   
Protein Interaction databases
DIP (DOE-UCLA)Q9NUR3
IntAct (EBI)Q9NUR3
FunCoupENSG00000125895
BioGRIDTMEM74B
STRING (EMBL)TMEM74B
ZODIACTMEM74B
Ontologies - Pathways
QuickGOQ9NUR3
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM74B
Atlas of Cancer Signalling NetworkTMEM74B
Wikipedia pathwaysTMEM74B
Orthology - Evolution
OrthoDB55321
GeneTree (enSembl)ENSG00000125895
Phylogenetic Trees/Animal Genes : TreeFamTMEM74B
HOVERGENQ9NUR3
HOGENOMQ9NUR3
Homologs : HomoloGeneTMEM74B
Homology/Alignments : Family Browser (UCSC)TMEM74B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM74B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM74B
dbVarTMEM74B
ClinVarTMEM74B
1000_GenomesTMEM74B 
Exome Variant ServerTMEM74B
ExAC (Exome Aggregation Consortium)TMEM74B (select the gene name)
Genetic variants : HAPMAP55321
Genomic Variants (DGV)TMEM74B [DGVbeta]
DECIPHERTMEM74B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM74B 
Mutations
ICGC Data PortalTMEM74B 
TCGA Data PortalTMEM74B 
Broad Tumor PortalTMEM74B
OASIS PortalTMEM74B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTMEM74B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM74B
DgiDB (Drug Gene Interaction Database)TMEM74B
DoCM (Curated mutations)TMEM74B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM74B (select a term)
intoGenTMEM74B
Cancer3DTMEM74B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMEM74B
Genetic Testing Registry TMEM74B
NextProtQ9NUR3 [Medical]
TSGene55321
GENETestsTMEM74B
Target ValidationTMEM74B
Huge Navigator TMEM74B [HugePedia]
snp3D : Map Gene to Disease55321
BioCentury BCIQTMEM74B
ClinGenTMEM74B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55321
Chemical/Pharm GKB GenePA25759
Clinical trialTMEM74B
Miscellaneous
canSAR (ICR)TMEM74B (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM74B
EVEXTMEM74B
GoPubMedTMEM74B
iHOPTMEM74B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:46:29 CEST 2017

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