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TMEM91 (transmembrane protein 91)

Identity

Alias (NCBI)DSPC3
IFITMD6
HGNC (Hugo) TMEM91
HGNC Alias symbFLJ27310
IFITMD6
HGNC Alias nameinterferon induced transmembrane protein domain containing 6
LocusID (NCBI) 641649
Atlas_Id 74992
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 41363947 and ends at 41384082 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCKDHA (19q13.2) / TMEM91 (19q13.2)JA040725 () / TMEM91 (19q13.2)PRPS1 (Xq22.3) / TMEM91 (19q13.2)
TMEM91 (19q13.2) / DTX4 (11q12.1)TMEM91 (19q13.2) / PI4KAP2 (22q11.21)TMEM91 (19q13.2) / TGFB1 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(19;19)(q13;q13) TGFB1/TMEM91
t(19;19)(q13;q13) TGFB1/TMEM91


External links

 

Nomenclature
HGNC (Hugo)TMEM91   32393
Cards
Entrez_Gene (NCBI)TMEM91    transmembrane protein 91
AliasesDSPC3; IFITMD6
GeneCards (Weizmann)TMEM91
Ensembl hg19 (Hinxton)ENSG00000142046 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142046 [Gene_View]  ENSG00000142046 [Sequence]  chr19:41363947-41384082 [Contig_View]  TMEM91 [Vega]
ICGC DataPortalENSG00000142046
TCGA cBioPortalTMEM91
AceView (NCBI)TMEM91
Genatlas (Paris)TMEM91
SOURCE (Princeton)TMEM91
Genetics Home Reference (NIH)TMEM91
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM91  -     chr19:41363947-41384082 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM91  -     19q13.2   [Description]    (hg19-Feb_2009)
GoldenPathTMEM91 - 19q13.2 [CytoView hg19]  TMEM91 - 19q13.2 [CytoView hg38]
ImmunoBaseENSG00000142046
Genome Data Viewer NCBITMEM91 [Mapview hg19]  
OMIM618294   
Gene and transcription
Genbank (Entrez)AI214374 AI277187 AK130820 AL833095 BC063705
RefSeq transcript (Entrez)NM_001042595 NM_001098821 NM_001098822 NM_001098823 NM_001098824 NM_001098825 NM_001369862 NM_001369864
Consensus coding sequences : CCDS (NCBI)TMEM91
Gene ExpressionTMEM91 [ NCBI-GEO ]   TMEM91 [ EBI - ARRAY_EXPRESS ]   TMEM91 [ SEEK ]   TMEM91 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM91 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM91 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)641649
GTEX Portal (Tissue expression)TMEM91
Human Protein AtlasENSG00000142046-TMEM91 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNR0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNR0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNR0
PhosPhoSitePlusQ6ZNR0
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)TMEM91
SuperfamilyQ6ZNR0
AlphaFold pdb e-kbQ6ZNR0   
Human Protein Atlas [tissue]ENSG00000142046-TMEM91 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNR0
IntAct (EBI)Q6ZNR0
BioGRIDTMEM91
STRING (EMBL)TMEM91
ZODIACTMEM91
Ontologies - Pathways
QuickGOQ6ZNR0
Ontology : AmiGOhematopoietic progenitor cell differentiation  molecular_function  cellular_component  biological_process  membrane  integral component of membrane  intracellular membrane-bounded organelle  
Ontology : EGO-EBIhematopoietic progenitor cell differentiation  molecular_function  cellular_component  biological_process  membrane  integral component of membrane  intracellular membrane-bounded organelle  
NDEx NetworkTMEM91
Atlas of Cancer Signalling NetworkTMEM91
Wikipedia pathwaysTMEM91
Orthology - Evolution
OrthoDB641649
GeneTree (enSembl)ENSG00000142046
Phylogenetic Trees/Animal Genes : TreeFamTMEM91
Homologs : HomoloGeneTMEM91
Homology/Alignments : Family Browser (UCSC)TMEM91
Gene fusions - Rearrangements
Fusion : QuiverTMEM91
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM91 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM91
dbVarTMEM91
ClinVarTMEM91
MonarchTMEM91
1000_GenomesTMEM91 
Exome Variant ServerTMEM91
GNOMAD BrowserENSG00000142046
Varsome BrowserTMEM91
ACMGTMEM91 variants
VarityQ6ZNR0
Genomic Variants (DGV)TMEM91 [DGVbeta]
DECIPHERTMEM91 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM91 
Mutations
ICGC Data PortalTMEM91 
TCGA Data PortalTMEM91 
Broad Tumor PortalTMEM91
OASIS PortalTMEM91 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM91  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM91
Mutations and Diseases : HGMDTMEM91
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM91
DgiDB (Drug Gene Interaction Database)TMEM91
DoCM (Curated mutations)TMEM91
CIViC (Clinical Interpretations of Variants in Cancer)TMEM91
Cancer3DTMEM91
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618294   
Orphanet
DisGeNETTMEM91
MedgenTMEM91
Genetic Testing Registry TMEM91
NextProtQ6ZNR0 [Medical]
GENETestsTMEM91
Target ValidationTMEM91
Huge Navigator TMEM91 [HugePedia]
ClinGenTMEM91
Clinical trials, drugs, therapy
MyCancerGenomeTMEM91
Protein Interactions : CTDTMEM91
Pharm GKB GenePA142670743
PharosQ6ZNR0
Clinical trialTMEM91
Miscellaneous
canSAR (ICR)TMEM91
HarmonizomeTMEM91
DataMed IndexTMEM91
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM91
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:26:22 CEST 2021

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