TMIGD2 (transmembrane and immunoglobulin domain containing 2)

2016-10-01  

Identity

HGNC
TMIGD2
LOCATION
19p13.3
LOCUSID
126259
ALIAS
CD28H,IGPR-1,IGPR1

Other Information

Locus ID:

NCBI: 126259
MIM: 614715
HGNC: 28324
Ensembl: ENSG00000167664

Variants:

dbSNP: 126259
ClinVar: 126259
TCGA: ENSG00000167664
COSMIC: TMIGD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167664ENST00000301272Q96BF3
ENSG00000167664ENST00000595645Q96BF3
ENSG00000167664ENST00000600114A0A0B4J2A9
ENSG00000167664ENST00000600349A0A0B4J2B0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
237840062013B7-H5 costimulates human T cells via CD28H.50
224198212012Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.27
278383212016IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function.8
305484412019B7-H5/CD28H is a co-stimulatory pathway and correlates with improved prognosis in pancreatic ductal adenocarcinoma.2
310893952019The Expression Patterns and Associated Clinical Parameters of Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 and Transmembrane and Immunoglobulin Domain Containing 2 in Oral Squamous Cell Carcinoma.1
313410212019The cell adhesion molecule IGPR-1 is activated by and regulates responses of endothelial cells to shear stress.0

Citation

Dessen P

TMIGD2 (transmembrane and immunoglobulin domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56115/tmigd2