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TMOD3 (tropomodulin 3)

Identity

Alias_symbol (synonym)UTMOD
Other alias
HGNC (Hugo) TMOD3
LocusID (NCBI) 29766
Atlas_Id 43998
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 52121825 and ends at 52204331 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MAPK6 (15q21.2) / TMOD3 (15q21.2)TMOD3 (15q21.2) / EIF4E2 (2q37.1)TMOD3 (15q21.2) / MCF2 (Xq27.1)
TMOD3 (15q21.2) / PJA2 (5q21.3)MAPK6 15q21.2 / TMOD3 15q21.2TMOD3 15q21.2 / EIF4E2 2q37.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMOD3   11873
Cards
Entrez_Gene (NCBI)TMOD3  29766  tropomodulin 3
AliasesUTMOD
GeneCards (Weizmann)TMOD3
Ensembl hg19 (Hinxton)ENSG00000138594 [Gene_View]  chr15:52121825-52204331 [Contig_View]  TMOD3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000138594 [Gene_View]  chr15:52121825-52204331 [Contig_View]  TMOD3 [Vega]
ICGC DataPortalENSG00000138594
TCGA cBioPortalTMOD3
AceView (NCBI)TMOD3
Genatlas (Paris)TMOD3
WikiGenes29766
SOURCE (Princeton)TMOD3
Genetics Home Reference (NIH)TMOD3
Genomic and cartography
GoldenPath hg19 (UCSC)TMOD3  -     chr15:52121825-52204331 +  15q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMOD3  -     15q21.2   [Description]    (hg38-Dec_2013)
EnsemblTMOD3 - 15q21.2 [CytoView hg19]  TMOD3 - 15q21.2 [CytoView hg38]
Mapping of homologs : NCBITMOD3 [Mapview hg19]  TMOD3 [Mapview hg38]
OMIM605112   
Gene and transcription
Genbank (Entrez)AF177171 AF237631 AK025704 AK310344 AK312569
RefSeq transcript (Entrez)NM_014547
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)TMOD3
Cluster EST : UnigeneHs.4998 [ NCBI ]
CGAP (NCI)Hs.4998
Alternative Splicing GalleryENSG00000138594
Gene ExpressionTMOD3 [ NCBI-GEO ]   TMOD3 [ EBI - ARRAY_EXPRESS ]   TMOD3 [ SEEK ]   TMOD3 [ MEM ]
Gene Expression Viewer (FireBrowse)TMOD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29766
GTEX Portal (Tissue expression)TMOD3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYL9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYL9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYL9
Splice isoforms : SwissVarQ9NYL9
PhosPhoSitePlusQ9NYL9
Domains : Interpro (EBI)L_dom-like    TMOD    TMOD3   
Domain families : Pfam (Sanger)Tropomodulin (PF03250)   
Domain families : Pfam (NCBI)pfam03250   
Conserved Domain (NCBI)TMOD3
DMDM Disease mutations29766
Blocks (Seattle)TMOD3
SuperfamilyQ9NYL9
Human Protein AtlasENSG00000138594
Peptide AtlasQ9NYL9
HPRD10389
IPIIPI00005087   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYL9
IntAct (EBI)Q9NYL9
FunCoupENSG00000138594
BioGRIDTMOD3
STRING (EMBL)TMOD3
ZODIACTMOD3
Ontologies - Pathways
QuickGOQ9NYL9
Ontology : AmiGOactin binding  tropomyosin binding  striated muscle thin filament  muscle contraction  actin filament organization  myofibril assembly  erythrocyte development  pointed-end actin filament capping  positive regulation of mitotic cell cycle phase transition  
Ontology : EGO-EBIactin binding  tropomyosin binding  striated muscle thin filament  muscle contraction  actin filament organization  myofibril assembly  erythrocyte development  pointed-end actin filament capping  positive regulation of mitotic cell cycle phase transition  
NDEx NetworkTMOD3
Atlas of Cancer Signalling NetworkTMOD3
Wikipedia pathwaysTMOD3
Orthology - Evolution
OrthoDB29766
GeneTree (enSembl)ENSG00000138594
Phylogenetic Trees/Animal Genes : TreeFamTMOD3
HOVERGENQ9NYL9
HOGENOMQ9NYL9
Homologs : HomoloGeneTMOD3
Homology/Alignments : Family Browser (UCSC)TMOD3
Gene fusions - Rearrangements
Fusion : MitelmanMAPK6/TMOD3 [15q21.2/15q21.2]  [t(15;15)(q21;q21)]  
Fusion : MitelmanTMOD3/EIF4E2 [15q21.2/2q37.1]  [t(2;15)(q37;q21)]  
Fusion: TCGAMAPK6 15q21.2 TMOD3 15q21.2 LGG
Fusion: TCGATMOD3 15q21.2 EIF4E2 2q37.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMOD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMOD3
dbVarTMOD3
ClinVarTMOD3
1000_GenomesTMOD3 
Exome Variant ServerTMOD3
ExAC (Exome Aggregation Consortium)TMOD3 (select the gene name)
Genetic variants : HAPMAP29766
Genomic Variants (DGV)TMOD3 [DGVbeta]
DECIPHER (Syndromes)15:52121825-52204331  ENSG00000138594
CONAN: Copy Number AnalysisTMOD3 
Mutations
ICGC Data PortalTMOD3 
TCGA Data PortalTMOD3 
Broad Tumor PortalTMOD3
OASIS PortalTMOD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMOD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMOD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMOD3
DgiDB (Drug Gene Interaction Database)TMOD3
DoCM (Curated mutations)TMOD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMOD3 (select a term)
intoGenTMOD3
Cancer3DTMOD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605112   
Orphanet
MedgenTMOD3
Genetic Testing Registry TMOD3
NextProtQ9NYL9 [Medical]
TSGene29766
GENETestsTMOD3
Huge Navigator TMOD3 [HugePedia]
snp3D : Map Gene to Disease29766
BioCentury BCIQTMOD3
ClinGenTMOD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29766
Chemical/Pharm GKB GenePA36574
Clinical trialTMOD3
Miscellaneous
canSAR (ICR)TMOD3 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMOD3
EVEXTMOD3
GoPubMedTMOD3
iHOPTMOD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:31:34 CET 2017

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