TMOD3 (tropomodulin 3)

2007-02-01  

Identity

HGNC
LOCATION
15q21.2
LOCUSID
ALIAS
UTMOD
FUSION GENES

Other Information

Locus ID:

NCBI: 29766
MIM: 605112
HGNC: 11873
Ensembl: ENSG00000138594

Variants:

dbSNP: 29766
ClinVar: 29766
TCGA: ENSG00000138594
COSMIC: TMOD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138594ENST00000308580Q9NYL9
ENSG00000138594ENST00000558455H0YNU8
ENSG00000138594ENST00000560549H0YNJ8
ENSG00000138594ENST00000561438H0YKU1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Striated Muscle ContractionREACTOMER-HSA-390522

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
127073102003Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility.43
179283072007Tmod3 regulates polarized epithelial cell morphology.42
170127452006Tropomodulin 3 binds to actin monomers.30
150953012004Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder.18
221580852012Identification and validation of novel serum markers for early diagnosis of endometriosis.9
268983452016Global proteomic profiling identifies etoposide chemoresistance markers in non-small cell lung carcinoma.6
313133922019Tropomodulin 3 modulates EGFR-PI3K-AKT signaling to drive hepatocellular carcinoma metastasis.4
308647302019Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway.2

Citation

Dessen P

TMOD3 (tropomodulin 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43998/tmod3