TMPO (thymopoietin)

2007-02-01  

Identity

HGNC
LOCATION
12q23.1
LOCUSID
ALIAS
CMD1T,LAP2,LEMD4,PRO0868,TP
FUSION GENES

Other Information

Locus ID:

NCBI: 7112
MIM: 188380
HGNC: 11875
Ensembl: ENSG00000120802

Variants:

dbSNP: 7112
ClinVar: 7112
TCGA: ENSG00000120802
COSMIC: TMPO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120802ENST00000261210P42167
ENSG00000120802ENST00000266732P42166
ENSG00000120802ENST00000343315G5E972
ENSG00000120802ENST00000393053P42167
ENSG00000120802ENST00000393053A0A024RBH7
ENSG00000120802ENST00000556029P42167
ENSG00000120802ENST00000556029A0A024RBE7
ENSG00000120802ENST00000556678H0YJH7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Nuclear Envelope BreakdownREACTOMER-HSA-2980766
Clearance of Nuclear Envelope Membranes from ChromatinREACTOMER-HSA-2993913
Depolymerisation of the Nuclear LaminaREACTOMER-HSA-4419969
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Nuclear Envelope ReassemblyREACTOMER-HSA-2995410
Initiation of Nuclear Envelope ReformationREACTOMER-HSA-2995383

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
357608752022LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription.11
357608752022LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription.11
329885992020LncRNA TMPO-AS1 Aggravates the Development of Hepatocellular Carcinoma via miR-429/GOT1 Axis.10
329885992020LncRNA TMPO-AS1 Aggravates the Development of Hepatocellular Carcinoma via miR-429/GOT1 Axis.10
312307522019Long noncoding RNA TMPO-AS1 promotes progression of non-small cell lung cancer through regulating its natural antisense transcript TMPO.23
312307522019Long noncoding RNA TMPO-AS1 promotes progression of non-small cell lung cancer through regulating its natural antisense transcript TMPO.23
277563192016Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.14
277563192016Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.14
258378472015Thymopoietin Beta and Gamma Isoforms as a Potential Diagnostic Molecular Marker for Breast Cancer: Preliminary Data.2
260929352015The lamin-A/C-LAP2α-BAF1 protein complex regulates mitotic spindle assembly and positioning.19
263125022015Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.65
264438482015Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins.40
258378472015Thymopoietin Beta and Gamma Isoforms as a Potential Diagnostic Molecular Marker for Breast Cancer: Preliminary Data.2
260929352015The lamin-A/C-LAP2α-BAF1 protein complex regulates mitotic spindle assembly and positioning.19
263125022015Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.65

Citation

Dessen P

TMPO (thymopoietin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45593/tmpo