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TMPRSS11A (transmembrane protease, serine 11A)

Identity

Alias_symbol (synonym)ECRG1
Other alias
HGNC (Hugo) TMPRSS11A
LocusID (NCBI) 339967
Atlas_Id 50093
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 68776019 and ends at 68829232 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RUFY3 (4q13.3) / TMPRSS11A (4q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMPRSS11A   27954
Cards
Entrez_Gene (NCBI)TMPRSS11A  339967  transmembrane protease, serine 11A
AliasesECRG1
GeneCards (Weizmann)TMPRSS11A
Ensembl hg19 (Hinxton)ENSG00000187054 [Gene_View]  chr4:68776019-68829232 [Contig_View]  TMPRSS11A [Vega]
Ensembl hg38 (Hinxton)ENSG00000187054 [Gene_View]  chr4:68776019-68829232 [Contig_View]  TMPRSS11A [Vega]
ICGC DataPortalENSG00000187054
TCGA cBioPortalTMPRSS11A
AceView (NCBI)TMPRSS11A
Genatlas (Paris)TMPRSS11A
WikiGenes339967
SOURCE (Princeton)TMPRSS11A
Genetics Home Reference (NIH)TMPRSS11A
Genomic and cartography
GoldenPath hg19 (UCSC)TMPRSS11A  -     chr4:68776019-68829232 -  4q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMPRSS11A  -     4q13.2   [Description]    (hg38-Dec_2013)
EnsemblTMPRSS11A - 4q13.2 [CytoView hg19]  TMPRSS11A - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBITMPRSS11A [Mapview hg19]  TMPRSS11A [Mapview hg38]
OMIM611704   
Gene and transcription
Genbank (Entrez)AF071882 AK131518 AK292950 AY498712 BC111796
RefSeq transcript (Entrez)NM_001114387 NM_182606
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)TMPRSS11A
Cluster EST : UnigeneHs.450110 [ NCBI ]
CGAP (NCI)Hs.450110
Alternative Splicing GalleryENSG00000187054
Gene ExpressionTMPRSS11A [ NCBI-GEO ]   TMPRSS11A [ EBI - ARRAY_EXPRESS ]   TMPRSS11A [ SEEK ]   TMPRSS11A [ MEM ]
Gene Expression Viewer (FireBrowse)TMPRSS11A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339967
GTEX Portal (Tissue expression)TMPRSS11A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMR5
Splice isoforms : SwissVarQ6ZMR5
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ6ZMR5
Domaine pattern : Prosite (Expaxy)SEA (PS50024)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Pept_S1A_HAT/DESC1    Peptidase_S1_PA    Peptidase_S1A    SEA_dom    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)SEA (PF01390)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam01390    pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TMPRSS11A
DMDM Disease mutations339967
Blocks (Seattle)TMPRSS11A
SuperfamilyQ6ZMR5
Human Protein AtlasENSG00000187054
Peptide AtlasQ6ZMR5
HPRD07123
IPIIPI00418563   IPI00855891   IPI00966836   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMR5
IntAct (EBI)Q6ZMR5
FunCoupENSG00000187054
BioGRIDTMPRSS11A
STRING (EMBL)TMPRSS11A
ZODIACTMPRSS11A
Ontologies - Pathways
QuickGOQ6ZMR5
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  cell cycle  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  cell cycle  
NDEx NetworkTMPRSS11A
Atlas of Cancer Signalling NetworkTMPRSS11A
Wikipedia pathwaysTMPRSS11A
Orthology - Evolution
OrthoDB339967
GeneTree (enSembl)ENSG00000187054
Phylogenetic Trees/Animal Genes : TreeFamTMPRSS11A
HOVERGENQ6ZMR5
HOGENOMQ6ZMR5
Homologs : HomoloGeneTMPRSS11A
Homology/Alignments : Family Browser (UCSC)TMPRSS11A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMPRSS11A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMPRSS11A
dbVarTMPRSS11A
ClinVarTMPRSS11A
1000_GenomesTMPRSS11A 
Exome Variant ServerTMPRSS11A
ExAC (Exome Aggregation Consortium)TMPRSS11A (select the gene name)
Genetic variants : HAPMAP339967
Genomic Variants (DGV)TMPRSS11A [DGVbeta]
DECIPHER (Syndromes)4:68776019-68829232  ENSG00000187054
CONAN: Copy Number AnalysisTMPRSS11A 
Mutations
ICGC Data PortalTMPRSS11A 
TCGA Data PortalTMPRSS11A 
Broad Tumor PortalTMPRSS11A
OASIS PortalTMPRSS11A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMPRSS11A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMPRSS11A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMPRSS11A
DgiDB (Drug Gene Interaction Database)TMPRSS11A
DoCM (Curated mutations)TMPRSS11A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMPRSS11A (select a term)
intoGenTMPRSS11A
Cancer3DTMPRSS11A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611704   
Orphanet
MedgenTMPRSS11A
Genetic Testing Registry TMPRSS11A
NextProtQ6ZMR5 [Medical]
TSGene339967
GENETestsTMPRSS11A
Huge Navigator TMPRSS11A [HugePedia]
snp3D : Map Gene to Disease339967
BioCentury BCIQTMPRSS11A
ClinGenTMPRSS11A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339967
Chemical/Pharm GKB GenePA142670726
Clinical trialTMPRSS11A
Miscellaneous
canSAR (ICR)TMPRSS11A (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMPRSS11A
EVEXTMPRSS11A
GoPubMedTMPRSS11A
iHOPTMPRSS11A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:31:34 CET 2017

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