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TMPRSS11D (transmembrane protease, serine 11D)

Identity

Other aliasHAT
HGNC (Hugo) TMPRSS11D
LocusID (NCBI) 9407
Atlas_Id 55889
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 68686594 and ends at 68749716 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMPRSS11D (4q13.2) / SPINK2 (4q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMPRSS11D   24059
Cards
Entrez_Gene (NCBI)TMPRSS11D  9407  transmembrane protease, serine 11D
AliasesHAT
GeneCards (Weizmann)TMPRSS11D
Ensembl hg19 (Hinxton)ENSG00000153802 [Gene_View]  chr4:68686594-68749716 [Contig_View]  TMPRSS11D [Vega]
Ensembl hg38 (Hinxton)ENSG00000153802 [Gene_View]  chr4:68686594-68749716 [Contig_View]  TMPRSS11D [Vega]
ICGC DataPortalENSG00000153802
TCGA cBioPortalTMPRSS11D
AceView (NCBI)TMPRSS11D
Genatlas (Paris)TMPRSS11D
WikiGenes9407
SOURCE (Princeton)TMPRSS11D
Genetics Home Reference (NIH)TMPRSS11D
Genomic and cartography
GoldenPath hg19 (UCSC)TMPRSS11D  -     chr4:68686594-68749716 -  4q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMPRSS11D  -     4q13.2   [Description]    (hg38-Dec_2013)
EnsemblTMPRSS11D - 4q13.2 [CytoView hg19]  TMPRSS11D - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBITMPRSS11D [Mapview hg19]  TMPRSS11D [Mapview hg38]
OMIM605369   
Gene and transcription
Genbank (Entrez)AB002134 AK094054 AK290289 AK296853 AL603214
RefSeq transcript (Entrez)NM_004262
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMPRSS11D
Cluster EST : UnigeneHs.132195 [ NCBI ]
CGAP (NCI)Hs.132195
Alternative Splicing GalleryENSG00000153802
Gene ExpressionTMPRSS11D [ NCBI-GEO ]   TMPRSS11D [ EBI - ARRAY_EXPRESS ]   TMPRSS11D [ SEEK ]   TMPRSS11D [ MEM ]
Gene Expression Viewer (FireBrowse)TMPRSS11D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9407
GTEX Portal (Tissue expression)TMPRSS11D
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60235   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60235  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60235
Splice isoforms : SwissVarO60235
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusO60235
Domaine pattern : Prosite (Expaxy)SEA (PS50024)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Pept_S1A_HAT/DESC1    Peptidase_S1_PA    Peptidase_S1A    SEA_dom    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)SEA (PF01390)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam01390    pfam00089   
Domain families : Smart (EMBL)SEA (SM00200)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TMPRSS11D
DMDM Disease mutations9407
Blocks (Seattle)TMPRSS11D
SuperfamilyO60235
Human Protein AtlasENSG00000153802
Peptide AtlasO60235
HPRD05642
IPIIPI00003542   IPI01012651   IPI00967204   
Protein Interaction databases
DIP (DOE-UCLA)O60235
IntAct (EBI)O60235
FunCoupENSG00000153802
BioGRIDTMPRSS11D
STRING (EMBL)TMPRSS11D
ZODIACTMPRSS11D
Ontologies - Pathways
QuickGOO60235
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  respiratory gaseous exchange  peptidase activity  extracellular exosome  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  respiratory gaseous exchange  peptidase activity  extracellular exosome  
NDEx NetworkTMPRSS11D
Atlas of Cancer Signalling NetworkTMPRSS11D
Wikipedia pathwaysTMPRSS11D
Orthology - Evolution
OrthoDB9407
GeneTree (enSembl)ENSG00000153802
Phylogenetic Trees/Animal Genes : TreeFamTMPRSS11D
HOVERGENO60235
HOGENOMO60235
Homologs : HomoloGeneTMPRSS11D
Homology/Alignments : Family Browser (UCSC)TMPRSS11D
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMPRSS11D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMPRSS11D
dbVarTMPRSS11D
ClinVarTMPRSS11D
1000_GenomesTMPRSS11D 
Exome Variant ServerTMPRSS11D
ExAC (Exome Aggregation Consortium)TMPRSS11D (select the gene name)
Genetic variants : HAPMAP9407
Genomic Variants (DGV)TMPRSS11D [DGVbeta]
DECIPHER (Syndromes)4:68686594-68749716  ENSG00000153802
CONAN: Copy Number AnalysisTMPRSS11D 
Mutations
ICGC Data PortalTMPRSS11D 
TCGA Data PortalTMPRSS11D 
Broad Tumor PortalTMPRSS11D
OASIS PortalTMPRSS11D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMPRSS11D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMPRSS11D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMPRSS11D
DgiDB (Drug Gene Interaction Database)TMPRSS11D
DoCM (Curated mutations)TMPRSS11D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMPRSS11D (select a term)
intoGenTMPRSS11D
Cancer3DTMPRSS11D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605369   
Orphanet
MedgenTMPRSS11D
Genetic Testing Registry TMPRSS11D
NextProtO60235 [Medical]
TSGene9407
GENETestsTMPRSS11D
Huge Navigator TMPRSS11D [HugePedia]
snp3D : Map Gene to Disease9407
BioCentury BCIQTMPRSS11D
ClinGenTMPRSS11D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9407
Chemical/Pharm GKB GenePA142670728
Clinical trialTMPRSS11D
Miscellaneous
canSAR (ICR)TMPRSS11D (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMPRSS11D
EVEXTMPRSS11D
GoPubMedTMPRSS11D
iHOPTMPRSS11D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:31:34 CET 2017

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