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TMPRSS11E (transmembrane protease, serine 11E)

Identity

Alias_namesTMPRSS11E2
transmembrane protease
Alias_symbol (synonym)DESC1
Other alias
HGNC (Hugo) TMPRSS11E
LocusID (NCBI) 28983
Atlas_Id 55905
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 68447449 and ends at 68497604 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC4A4 (4q13.3) / TMPRSS11E (4q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMPRSS11E   24465
Cards
Entrez_Gene (NCBI)TMPRSS11E  28983  transmembrane protease, serine 11E
AliasesDESC1; TMPRSS11E2
GeneCards (Weizmann)TMPRSS11E
Ensembl hg19 (Hinxton)ENSG00000087128 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087128 [Gene_View]  chr4:68447449-68497604 [Contig_View]  TMPRSS11E [Vega]
ICGC DataPortalENSG00000087128
TCGA cBioPortalTMPRSS11E
AceView (NCBI)TMPRSS11E
Genatlas (Paris)TMPRSS11E
WikiGenes28983
SOURCE (Princeton)TMPRSS11E
Genetics Home Reference (NIH)TMPRSS11E
Genomic and cartography
GoldenPath hg38 (UCSC)TMPRSS11E  -     chr4:68447449-68497604 +  4q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMPRSS11E  -     4q13.2   [Description]    (hg19-Feb_2009)
EnsemblTMPRSS11E - 4q13.2 [CytoView hg19]  TMPRSS11E - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBITMPRSS11E [Mapview hg19]  TMPRSS11E [Mapview hg38]
OMIM610399   
Gene and transcription
Genbank (Entrez)AF064819 AK292787 AK313859 AY359017 BC113412
RefSeq transcript (Entrez)NM_014058
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_167250
Consensus coding sequences : CCDS (NCBI)TMPRSS11E
Cluster EST : UnigeneHs.201877 [ NCBI ]
CGAP (NCI)Hs.201877
Alternative Splicing GalleryENSG00000087128
Gene ExpressionTMPRSS11E [ NCBI-GEO ]   TMPRSS11E [ EBI - ARRAY_EXPRESS ]   TMPRSS11E [ SEEK ]   TMPRSS11E [ MEM ]
Gene Expression Viewer (FireBrowse)TMPRSS11E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28983
GTEX Portal (Tissue expression)TMPRSS11E
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UL52   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UL52  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UL52
Splice isoforms : SwissVarQ9UL52
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ9UL52
Domaine pattern : Prosite (Expaxy)SEA (PS50024)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Pept_S1A_HAT/DESC1    Peptidase_S1_PA    Peptidase_S1A    SEA_dom    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)SEA (PF01390)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam01390    pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TMPRSS11E
DMDM Disease mutations28983
Blocks (Seattle)TMPRSS11E
PDB (SRS)2OQ5   
PDB (PDBSum)2OQ5   
PDB (IMB)2OQ5   
PDB (RSDB)2OQ5   
Structural Biology KnowledgeBase2OQ5   
SCOP (Structural Classification of Proteins)2OQ5   
CATH (Classification of proteins structures)2OQ5   
SuperfamilyQ9UL52
Human Protein AtlasENSG00000087128
Peptide AtlasQ9UL52
HPRD09912
IPIIPI00297030   IPI00964712   
Protein Interaction databases
DIP (DOE-UCLA)Q9UL52
IntAct (EBI)Q9UL52
FunCoupENSG00000087128
BioGRIDTMPRSS11E
STRING (EMBL)TMPRSS11E
ZODIACTMPRSS11E
Ontologies - Pathways
QuickGOQ9UL52
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  serine-type peptidase activity  cognition  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  integral component of plasma membrane  proteolysis  serine-type peptidase activity  cognition  
NDEx NetworkTMPRSS11E
Atlas of Cancer Signalling NetworkTMPRSS11E
Wikipedia pathwaysTMPRSS11E
Orthology - Evolution
OrthoDB28983
GeneTree (enSembl)ENSG00000087128
Phylogenetic Trees/Animal Genes : TreeFamTMPRSS11E
HOVERGENQ9UL52
HOGENOMQ9UL52
Homologs : HomoloGeneTMPRSS11E
Homology/Alignments : Family Browser (UCSC)TMPRSS11E
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMPRSS11E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMPRSS11E
dbVarTMPRSS11E
ClinVarTMPRSS11E
1000_GenomesTMPRSS11E 
Exome Variant ServerTMPRSS11E
ExAC (Exome Aggregation Consortium)TMPRSS11E (select the gene name)
Genetic variants : HAPMAP28983
Genomic Variants (DGV)TMPRSS11E [DGVbeta]
DECIPHERTMPRSS11E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMPRSS11E 
Mutations
ICGC Data PortalTMPRSS11E 
TCGA Data PortalTMPRSS11E 
Broad Tumor PortalTMPRSS11E
OASIS PortalTMPRSS11E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMPRSS11E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMPRSS11E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMPRSS11E
DgiDB (Drug Gene Interaction Database)TMPRSS11E
DoCM (Curated mutations)TMPRSS11E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMPRSS11E (select a term)
intoGenTMPRSS11E
Cancer3DTMPRSS11E(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610399   
Orphanet
MedgenTMPRSS11E
Genetic Testing Registry TMPRSS11E
NextProtQ9UL52 [Medical]
TSGene28983
GENETestsTMPRSS11E
Huge Navigator TMPRSS11E [HugePedia]
snp3D : Map Gene to Disease28983
BioCentury BCIQTMPRSS11E
ClinGenTMPRSS11E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28983
Chemical/Pharm GKB GenePA142670729
Clinical trialTMPRSS11E
Miscellaneous
canSAR (ICR)TMPRSS11E (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMPRSS11E
EVEXTMPRSS11E
GoPubMedTMPRSS11E
iHOPTMPRSS11E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:41:29 CEST 2017

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