Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMPRSS12 (transmembrane serine protease 12)

Identity

Alias (NCBI)CT151
HGNC (Hugo) TMPRSS12
HGNC Alias symbMGC57341
CT151
HGNC Previous nametransmembrane protease, serine 12
 transmembrane (C-terminal) protease, serine 12
LocusID (NCBI) 283471
Atlas_Id 75013
Location 12q13.12  [Link to chromosome band 12q13]
Location_base_pair Starts at 50842926 and ends at 50887880 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMPRSS12 (12q13.12) / KIF27 (9q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMPRSS12   28779
Cards
Entrez_Gene (NCBI)TMPRSS12    transmembrane serine protease 12
AliasesCT151
GeneCards (Weizmann)TMPRSS12
Ensembl hg19 (Hinxton)ENSG00000186452 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186452 [Gene_View]  ENSG00000186452 [Sequence]  chr12:50842926-50887880 [Contig_View]  TMPRSS12 [Vega]
ICGC DataPortalENSG00000186452
TCGA cBioPortalTMPRSS12
AceView (NCBI)TMPRSS12
Genatlas (Paris)TMPRSS12
SOURCE (Princeton)TMPRSS12
Genetics Home Reference (NIH)TMPRSS12
Genomic and cartography
GoldenPath hg38 (UCSC)TMPRSS12  -     chr12:50842926-50887880 +  12q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMPRSS12  -     12q13.12   [Description]    (hg19-Feb_2009)
GoldenPathTMPRSS12 - 12q13.12 [CytoView hg19]  TMPRSS12 - 12q13.12 [CytoView hg38]
ImmunoBaseENSG00000186452
Genome Data Viewer NCBITMPRSS12 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA884376 BC035123 BC048112 DB458497 HM005521
RefSeq transcript (Entrez)NM_182559
Consensus coding sequences : CCDS (NCBI)TMPRSS12
Gene ExpressionTMPRSS12 [ NCBI-GEO ]   TMPRSS12 [ EBI - ARRAY_EXPRESS ]   TMPRSS12 [ SEEK ]   TMPRSS12 [ MEM ]
Gene Expression Viewer (FireBrowse)TMPRSS12 [ Firebrowse - Broad ]
GenevisibleExpression of TMPRSS12 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283471
GTEX Portal (Tissue expression)TMPRSS12
Human Protein AtlasENSG00000186452-TMPRSS12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86WS5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86WS5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86WS5
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ86WS5
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1_PA_chymotrypsin    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TMPRSS12
SuperfamilyQ86WS5
AlphaFold pdb e-kbQ86WS5   
Human Protein Atlas [tissue]ENSG00000186452-TMPRSS12 [tissue]
HPRD07133
Protein Interaction databases
DIP (DOE-UCLA)Q86WS5
IntAct (EBI)Q86WS5
BioGRIDTMPRSS12
STRING (EMBL)TMPRSS12
ZODIACTMPRSS12
Ontologies - Pathways
QuickGOQ86WS5
Ontology : AmiGOacrosomal vesicle  serine-type endopeptidase activity  binding of sperm to zona pellucida  integral component of membrane  protein processing  
Ontology : EGO-EBIacrosomal vesicle  serine-type endopeptidase activity  binding of sperm to zona pellucida  integral component of membrane  protein processing  
NDEx NetworkTMPRSS12
Atlas of Cancer Signalling NetworkTMPRSS12
Wikipedia pathwaysTMPRSS12
Orthology - Evolution
OrthoDB283471
GeneTree (enSembl)ENSG00000186452
Phylogenetic Trees/Animal Genes : TreeFamTMPRSS12
Homologs : HomoloGeneTMPRSS12
Homology/Alignments : Family Browser (UCSC)TMPRSS12
Gene fusions - Rearrangements
Fusion : QuiverTMPRSS12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMPRSS12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMPRSS12
dbVarTMPRSS12
ClinVarTMPRSS12
MonarchTMPRSS12
1000_GenomesTMPRSS12 
Exome Variant ServerTMPRSS12
GNOMAD BrowserENSG00000186452
Varsome BrowserTMPRSS12
ACMGTMPRSS12 variants
VarityQ86WS5
Genomic Variants (DGV)TMPRSS12 [DGVbeta]
DECIPHERTMPRSS12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMPRSS12 
Mutations
ICGC Data PortalTMPRSS12 
TCGA Data PortalTMPRSS12 
Broad Tumor PortalTMPRSS12
OASIS PortalTMPRSS12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMPRSS12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMPRSS12
Mutations and Diseases : HGMDTMPRSS12
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMPRSS12
DgiDB (Drug Gene Interaction Database)TMPRSS12
DoCM (Curated mutations)TMPRSS12
CIViC (Clinical Interpretations of Variants in Cancer)TMPRSS12
Cancer3DTMPRSS12
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMPRSS12
MedgenTMPRSS12
Genetic Testing Registry TMPRSS12
NextProtQ86WS5 [Medical]
GENETestsTMPRSS12
Target ValidationTMPRSS12
Huge Navigator TMPRSS12 [HugePedia]
ClinGenTMPRSS12
Clinical trials, drugs, therapy
MyCancerGenomeTMPRSS12
Protein Interactions : CTDTMPRSS12
Pharm GKB GenePA142670731
PharosQ86WS5
Clinical trialTMPRSS12
Miscellaneous
canSAR (ICR)TMPRSS12
HarmonizomeTMPRSS12
DataMed IndexTMPRSS12
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMPRSS12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:26:26 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.