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TMPRSS7 (transmembrane protease, serine 7)

Identity

Alias_namestype II transmembrane serine protease 7
Other alias-
HGNC (Hugo) TMPRSS7
LocusID (NCBI) 344805
Atlas_Id 55549
Location 3q13.2  [Link to chromosome band 3q13]
Location_base_pair Starts at 112039618 and ends at 112081269 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HSPE1 (2q33.1) / TMPRSS7 (3q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMPRSS7   30846
Cards
Entrez_Gene (NCBI)TMPRSS7  344805  transmembrane protease, serine 7
Aliases
GeneCards (Weizmann)TMPRSS7
Ensembl hg19 (Hinxton)ENSG00000176040 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176040 [Gene_View]  chr3:112039618-112081269 [Contig_View]  TMPRSS7 [Vega]
ICGC DataPortalENSG00000176040
TCGA cBioPortalTMPRSS7
AceView (NCBI)TMPRSS7
Genatlas (Paris)TMPRSS7
WikiGenes344805
SOURCE (Princeton)TMPRSS7
Genetics Home Reference (NIH)TMPRSS7
Genomic and cartography
GoldenPath hg38 (UCSC)TMPRSS7  -     chr3:112039618-112081269 +  3q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMPRSS7  -     3q13.2   [Description]    (hg19-Feb_2009)
EnsemblTMPRSS7 - 3q13.2 [CytoView hg19]  TMPRSS7 - 3q13.2 [CytoView hg38]
Mapping of homologs : NCBITMPRSS7 [Mapview hg19]  TMPRSS7 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK131211 BC117322 BN000125
RefSeq transcript (Entrez)NM_001042575
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMPRSS7
Cluster EST : UnigeneHs.435490 [ NCBI ]
CGAP (NCI)Hs.435490
Alternative Splicing GalleryENSG00000176040
Gene ExpressionTMPRSS7 [ NCBI-GEO ]   TMPRSS7 [ EBI - ARRAY_EXPRESS ]   TMPRSS7 [ SEEK ]   TMPRSS7 [ MEM ]
Gene Expression Viewer (FireBrowse)TMPRSS7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344805
GTEX Portal (Tissue expression)TMPRSS7
Human Protein AtlasENSG00000176040-TMPRSS7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTY8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTY8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTY8
Splice isoforms : SwissVarQ7RTY8
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ7RTY8
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    LDLRA_1 (PS01209)    LDLRA_2 (PS50068)    SEA (PS50024)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)CUB_dom    LDLR_class-A_CS    LDrepeatLR_classA_rpt    Peptidase_S1_PA    Peptidase_S1A    SEA_dom    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)CUB (PF00431)    Ldl_recept_a (PF00057)    SEA (PF01390)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00431    pfam00057    pfam01390    pfam00089   
Domain families : Smart (EMBL)CUB (SM00042)  LDLa (SM00192)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TMPRSS7
DMDM Disease mutations344805
Blocks (Seattle)TMPRSS7
SuperfamilyQ7RTY8
Human Protein Atlas [tissue]ENSG00000176040-TMPRSS7 [tissue]
Peptide AtlasQ7RTY8
IPIIPI00915469   IPI00941864   IPI00940406   IPI01021664   IPI01018054   IPI00927561   
Protein Interaction databases
DIP (DOE-UCLA)Q7RTY8
IntAct (EBI)Q7RTY8
FunCoupENSG00000176040
BioGRIDTMPRSS7
STRING (EMBL)TMPRSS7
ZODIACTMPRSS7
Ontologies - Pathways
QuickGOQ7RTY8
Ontology : AmiGOserine-type endopeptidase activity  plasma membrane  proteolysis  serine-type peptidase activity  integral component of membrane  
Ontology : EGO-EBIserine-type endopeptidase activity  plasma membrane  proteolysis  serine-type peptidase activity  integral component of membrane  
NDEx NetworkTMPRSS7
Atlas of Cancer Signalling NetworkTMPRSS7
Wikipedia pathwaysTMPRSS7
Orthology - Evolution
OrthoDB344805
GeneTree (enSembl)ENSG00000176040
Phylogenetic Trees/Animal Genes : TreeFamTMPRSS7
HOVERGENQ7RTY8
HOGENOMQ7RTY8
Homologs : HomoloGeneTMPRSS7
Homology/Alignments : Family Browser (UCSC)TMPRSS7
Gene fusions - Rearrangements
Tumor Fusion PortalTMPRSS7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMPRSS7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMPRSS7
dbVarTMPRSS7
ClinVarTMPRSS7
1000_GenomesTMPRSS7 
Exome Variant ServerTMPRSS7
ExAC (Exome Aggregation Consortium)ENSG00000176040
GNOMAD BrowserENSG00000176040
Genetic variants : HAPMAP344805
Genomic Variants (DGV)TMPRSS7 [DGVbeta]
DECIPHERTMPRSS7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMPRSS7 
Mutations
ICGC Data PortalTMPRSS7 
TCGA Data PortalTMPRSS7 
Broad Tumor PortalTMPRSS7
OASIS PortalTMPRSS7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMPRSS7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMPRSS7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMPRSS7
DgiDB (Drug Gene Interaction Database)TMPRSS7
DoCM (Curated mutations)TMPRSS7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMPRSS7 (select a term)
intoGenTMPRSS7
Cancer3DTMPRSS7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMPRSS7
MedgenTMPRSS7
Genetic Testing Registry TMPRSS7
NextProtQ7RTY8 [Medical]
TSGene344805
GENETestsTMPRSS7
Target ValidationTMPRSS7
Huge Navigator TMPRSS7 [HugePedia]
snp3D : Map Gene to Disease344805
BioCentury BCIQTMPRSS7
ClinGenTMPRSS7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD344805
Chemical/Pharm GKB GenePA134928796
Clinical trialTMPRSS7
Miscellaneous
canSAR (ICR)TMPRSS7 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMPRSS7
EVEXTMPRSS7
GoPubMedTMPRSS7
iHOPTMPRSS7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:38:58 CET 2017

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