Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMSB4X (thymosin beta 4, X-linked)

Identity

Alias_namesTMSB4
thymosin
Alias_symbol (synonym)TB4X
Other aliasFX
PTMB4
HGNC (Hugo) TMSB4X
LocusID (NCBI) 7114
Atlas_Id 42596
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 12993226 and ends at 12995346 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMSB4X (Xp22.2) / CROCC (1p36.13)TMSB4X (Xp22.2) / SC5D (11q23.3)TMSB4X (Xp22.2) / TSPAN7 (Xp11.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMSB4X   11881
Cards
Entrez_Gene (NCBI)TMSB4X  7114  thymosin beta 4, X-linked
AliasesFX; PTMB4; TB4X; TMSB4
GeneCards (Weizmann)TMSB4X
Ensembl hg19 (Hinxton)ENSG00000205542 [Gene_View]  chrX:12993226-12995346 [Contig_View]  TMSB4X [Vega]
Ensembl hg38 (Hinxton)ENSG00000205542 [Gene_View]  chrX:12993226-12995346 [Contig_View]  TMSB4X [Vega]
ICGC DataPortalENSG00000205542
TCGA cBioPortalTMSB4X
AceView (NCBI)TMSB4X
Genatlas (Paris)TMSB4X
WikiGenes7114
SOURCE (Princeton)TMSB4X
Genetics Home Reference (NIH)TMSB4X
Genomic and cartography
GoldenPath hg19 (UCSC)TMSB4X  -     chrX:12993226-12995346 +  Xp22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMSB4X  -     Xp22.2   [Description]    (hg38-Dec_2013)
EnsemblTMSB4X - Xp22.2 [CytoView hg19]  TMSB4X - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBITMSB4X [Mapview hg19]  TMSB4X [Mapview hg38]
OMIM300159   
Gene and transcription
Genbank (Entrez)AK055976 AK057827 AK311747 AV715954 BC001631
RefSeq transcript (Entrez)NM_021109
RefSeq genomic (Entrez)NC_000023 NC_018934 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)TMSB4X
Cluster EST : UnigeneHs.703237 [ NCBI ]
CGAP (NCI)Hs.703237
Alternative Splicing GalleryENSG00000205542
Gene ExpressionTMSB4X [ NCBI-GEO ]   TMSB4X [ EBI - ARRAY_EXPRESS ]   TMSB4X [ SEEK ]   TMSB4X [ MEM ]
Gene Expression Viewer (FireBrowse)TMSB4X [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7114
GTEX Portal (Tissue expression)TMSB4X
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62328   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62328  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62328
Splice isoforms : SwissVarP62328
PhosPhoSitePlusP62328
Domaine pattern : Prosite (Expaxy)THYMOSIN_B4 (PS00500)   
Domains : Interpro (EBI)Beta-thymosin   
Domain families : Pfam (Sanger)Thymosin (PF01290)   
Domain families : Pfam (NCBI)pfam01290   
Domain families : Smart (EMBL)THY (SM00152)  
Domain structure : Prodom (Prabi Lyon)Thymosin_b4 (PD005116)   
Conserved Domain (NCBI)TMSB4X
DMDM Disease mutations7114
Blocks (Seattle)TMSB4X
PDB (SRS)1UY5    3TU5    4PL7    4PL8   
PDB (PDBSum)1UY5    3TU5    4PL7    4PL8   
PDB (IMB)1UY5    3TU5    4PL7    4PL8   
PDB (RSDB)1UY5    3TU5    4PL7    4PL8   
Structural Biology KnowledgeBase1UY5    3TU5    4PL7    4PL8   
SCOP (Structural Classification of Proteins)1UY5    3TU5    4PL7    4PL8   
CATH (Classification of proteins structures)1UY5    3TU5    4PL7    4PL8   
SuperfamilyP62328
Human Protein AtlasENSG00000205542
Peptide AtlasP62328
HPRD02153
IPIIPI00220828   IPI00815642   IPI01012854   IPI01013265   IPI01011913   IPI01014272   
Protein Interaction databases
DIP (DOE-UCLA)P62328
IntAct (EBI)P62328
FunCoupENSG00000205542
BioGRIDTMSB4X
STRING (EMBL)TMSB4X
ZODIACTMSB4X
Ontologies - Pathways
QuickGOP62328
Ontology : AmiGOosteoblast differentiation  platelet degranulation  actin monomer binding  protein binding  extracellular region  nucleus  cytosol  cytoskeleton  actin filament organization  regulation of cell migration  platelet alpha granule lumen  poly(A) RNA binding  
Ontology : EGO-EBIosteoblast differentiation  platelet degranulation  actin monomer binding  protein binding  extracellular region  nucleus  cytosol  cytoskeleton  actin filament organization  regulation of cell migration  platelet alpha granule lumen  poly(A) RNA binding  
Pathways : KEGGRegulation of actin cytoskeleton   
NDEx NetworkTMSB4X
Atlas of Cancer Signalling NetworkTMSB4X
Wikipedia pathwaysTMSB4X
Orthology - Evolution
OrthoDB7114
GeneTree (enSembl)ENSG00000205542
Phylogenetic Trees/Animal Genes : TreeFamTMSB4X
HOVERGENP62328
HOGENOMP62328
Homologs : HomoloGeneTMSB4X
Homology/Alignments : Family Browser (UCSC)TMSB4X
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMSB4X [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMSB4X
dbVarTMSB4X
ClinVarTMSB4X
1000_GenomesTMSB4X 
Exome Variant ServerTMSB4X
ExAC (Exome Aggregation Consortium)TMSB4X (select the gene name)
Genetic variants : HAPMAP7114
Genomic Variants (DGV)TMSB4X [DGVbeta]
DECIPHER (Syndromes)X:12993226-12995346  ENSG00000205542
CONAN: Copy Number AnalysisTMSB4X 
Mutations
ICGC Data PortalTMSB4X 
TCGA Data PortalTMSB4X 
Broad Tumor PortalTMSB4X
OASIS PortalTMSB4X [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMSB4X  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMSB4X
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMSB4X
DgiDB (Drug Gene Interaction Database)TMSB4X
DoCM (Curated mutations)TMSB4X (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMSB4X (select a term)
intoGenTMSB4X
Cancer3DTMSB4X(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300159   
Orphanet
MedgenTMSB4X
Genetic Testing Registry TMSB4X
NextProtP62328 [Medical]
TSGene7114
GENETestsTMSB4X
Huge Navigator TMSB4X [HugePedia]
snp3D : Map Gene to Disease7114
BioCentury BCIQTMSB4X
ClinGenTMSB4X
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7114
Chemical/Pharm GKB GenePA36581
Clinical trialTMSB4X
Miscellaneous
canSAR (ICR)TMSB4X (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMSB4X
EVEXTMSB4X
GoPubMedTMSB4X
iHOPTMSB4X
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:22:51 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.