Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TMX1 (thioredoxin related transmembrane protein 1)

Identity

Alias_namesTXNDC
TXNDC1
thioredoxin domain-containing
thioredoxin domain containing
thioredoxin domain containing 1
thioredoxin-related transmembrane protein 1
Alias_symbol (synonym)TMX
PDIA11
Other alias
HGNC (Hugo) TMX1
LocusID (NCBI) 81542
Atlas_Id 75027
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 51240168 and ends at 51257654 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMX1   15487
Cards
Entrez_Gene (NCBI)TMX1  81542  thioredoxin related transmembrane protein 1
AliasesPDIA11; TMX; TXNDC; TXNDC1
GeneCards (Weizmann)TMX1
Ensembl hg19 (Hinxton)ENSG00000139921 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139921 [Gene_View]  chr14:51240168-51257654 [Contig_View]  TMX1 [Vega]
ICGC DataPortalENSG00000139921
TCGA cBioPortalTMX1
AceView (NCBI)TMX1
Genatlas (Paris)TMX1
WikiGenes81542
SOURCE (Princeton)TMX1
Genetics Home Reference (NIH)TMX1
Genomic and cartography
GoldenPath hg38 (UCSC)TMX1  -     chr14:51240168-51257654 +  14q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMX1  -     14q22.1   [Description]    (hg19-Feb_2009)
EnsemblTMX1 - 14q22.1 [CytoView hg19]  TMX1 - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBITMX1 [Mapview hg19]  TMX1 [Mapview hg38]
OMIM610527   
Gene and transcription
Genbank (Entrez)AB048246 AK075395 AK302416 AK303134 AK312905
RefSeq transcript (Entrez)NM_030755
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMX1
Cluster EST : UnigeneHs.125221 [ NCBI ]
CGAP (NCI)Hs.125221
Alternative Splicing GalleryENSG00000139921
Gene ExpressionTMX1 [ NCBI-GEO ]   TMX1 [ EBI - ARRAY_EXPRESS ]   TMX1 [ SEEK ]   TMX1 [ MEM ]
Gene Expression Viewer (FireBrowse)TMX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81542
GTEX Portal (Tissue expression)TMX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3N1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3N1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3N1
Splice isoforms : SwissVarQ9H3N1
PhosPhoSitePlusQ9H3N1
Domaine pattern : Prosite (Expaxy)THIOREDOXIN_1 (PS00194)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)Thioredoxin-like_fold    Thioredoxin_CS    Thioredoxin_domain   
Domain families : Pfam (Sanger)Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam00085   
Conserved Domain (NCBI)TMX1
DMDM Disease mutations81542
Blocks (Seattle)TMX1
PDB (SRS)1X5E   
PDB (PDBSum)1X5E   
PDB (IMB)1X5E   
PDB (RSDB)1X5E   
Structural Biology KnowledgeBase1X5E   
SCOP (Structural Classification of Proteins)1X5E   
CATH (Classification of proteins structures)1X5E   
SuperfamilyQ9H3N1
Human Protein AtlasENSG00000139921
Peptide AtlasQ9H3N1
HPRD15590
IPIIPI00395887   IPI00908319   IPI01024937   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3N1
IntAct (EBI)Q9H3N1
FunCoupENSG00000139921
BioGRIDTMX1
STRING (EMBL)TMX1
ZODIACTMX1
Ontologies - Pathways
QuickGOQ9H3N1
Ontology : AmiGOprotein disulfide isomerase activity  endoplasmic reticulum membrane  protein folding  disulfide oxidoreductase activity  integral component of membrane  response to endoplasmic reticulum stress  cell redox homeostasis  oxidation-reduction process  
Ontology : EGO-EBIprotein disulfide isomerase activity  endoplasmic reticulum membrane  protein folding  disulfide oxidoreductase activity  integral component of membrane  response to endoplasmic reticulum stress  cell redox homeostasis  oxidation-reduction process  
NDEx NetworkTMX1
Atlas of Cancer Signalling NetworkTMX1
Wikipedia pathwaysTMX1
Orthology - Evolution
OrthoDB81542
GeneTree (enSembl)ENSG00000139921
Phylogenetic Trees/Animal Genes : TreeFamTMX1
HOVERGENQ9H3N1
HOGENOMQ9H3N1
Homologs : HomoloGeneTMX1
Homology/Alignments : Family Browser (UCSC)TMX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMX1
dbVarTMX1
ClinVarTMX1
1000_GenomesTMX1 
Exome Variant ServerTMX1
ExAC (Exome Aggregation Consortium)TMX1 (select the gene name)
Genetic variants : HAPMAP81542
Genomic Variants (DGV)TMX1 [DGVbeta]
DECIPHERTMX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMX1 
Mutations
ICGC Data PortalTMX1 
TCGA Data PortalTMX1 
Broad Tumor PortalTMX1
OASIS PortalTMX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMX1
DgiDB (Drug Gene Interaction Database)TMX1
DoCM (Curated mutations)TMX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMX1 (select a term)
intoGenTMX1
Cancer3DTMX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610527   
Orphanet
MedgenTMX1
Genetic Testing Registry TMX1
NextProtQ9H3N1 [Medical]
TSGene81542
GENETestsTMX1
Target ValidationTMX1
Huge Navigator TMX1 [HugePedia]
snp3D : Map Gene to Disease81542
BioCentury BCIQTMX1
ClinGenTMX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81542
Chemical/Pharm GKB GenePA37968
Clinical trialTMX1
Miscellaneous
canSAR (ICR)TMX1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMX1
EVEXTMX1
GoPubMedTMX1
iHOPTMX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:46:38 CEST 2017

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