Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TMX3 (thioredoxin-related transmembrane protein 3)

Identity

Alias_namesTXNDC10
thioredoxin domain containing 10
thioredoxin-related transmembrane protein 3
Alias_symbol (synonym)FLJ20793
KIAA1830
PDIA13
Other alias
HGNC (Hugo) TMX3
LocusID (NCBI) 54495
Atlas_Id 75030
Location 18q22.1  [Link to chromosome band 18q22]
Location_base_pair Starts at 66340925 and ends at 66382353 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMX3 (18q22.1) / METTL4 (18p11.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMX3   24718
Cards
Entrez_Gene (NCBI)TMX3  54495  thioredoxin-related transmembrane protein 3
AliasesPDIA13; TXNDC10
GeneCards (Weizmann)TMX3
Ensembl hg19 (Hinxton)ENSG00000166479 [Gene_View]  chr18:66340925-66382353 [Contig_View]  TMX3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000166479 [Gene_View]  chr18:66340925-66382353 [Contig_View]  TMX3 [Vega]
ICGC DataPortalENSG00000166479
TCGA cBioPortalTMX3
AceView (NCBI)TMX3
Genatlas (Paris)TMX3
WikiGenes54495
SOURCE (Princeton)TMX3
Genetics Home Reference (NIH)TMX3
Genomic and cartography
GoldenPath hg19 (UCSC)TMX3  -     chr18:66340925-66382353 -  18q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMX3  -     18q22.1   [Description]    (hg38-Dec_2013)
EnsemblTMX3 - 18q22.1 [CytoView hg19]  TMX3 - 18q22.1 [CytoView hg38]
Mapping of homologs : NCBITMX3 [Mapview hg19]  TMX3 [Mapview hg38]
OMIM616102   
Gene and transcription
Genbank (Entrez)AB058733 AK000800 AK025025 AK122715 AK295551
RefSeq transcript (Entrez)NM_019022
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929411
Consensus coding sequences : CCDS (NCBI)TMX3
Cluster EST : UnigeneHs.440534 [ NCBI ]
CGAP (NCI)Hs.440534
Alternative Splicing GalleryENSG00000166479
Gene ExpressionTMX3 [ NCBI-GEO ]   TMX3 [ EBI - ARRAY_EXPRESS ]   TMX3 [ SEEK ]   TMX3 [ MEM ]
Gene Expression Viewer (FireBrowse)TMX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54495
GTEX Portal (Tissue expression)TMX3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JJ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JJ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JJ7
Splice isoforms : SwissVarQ96JJ7
Catalytic activity : Enzyme5.3.4.1 [ Enzyme-Expasy ]   5.3.4.15.3.4.1 [ IntEnz-EBI ]   5.3.4.1 [ BRENDA ]   5.3.4.1 [ KEGG ]   
PhosPhoSitePlusQ96JJ7
Domaine pattern : Prosite (Expaxy)THIOREDOXIN_1 (PS00194)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)Thioredoxin-like_fold    Thioredoxin_CS    Thioredoxin_domain   
Domain families : Pfam (Sanger)Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam00085   
Conserved Domain (NCBI)TMX3
DMDM Disease mutations54495
Blocks (Seattle)TMX3
SuperfamilyQ96JJ7
Human Protein AtlasENSG00000166479
Peptide AtlasQ96JJ7
HPRD15591
IPIIPI00064193   IPI00645851   IPI00555585   
Protein Interaction databases
DIP (DOE-UCLA)Q96JJ7
IntAct (EBI)Q96JJ7
FunCoupENSG00000166479
BioGRIDTMX3
STRING (EMBL)TMX3
ZODIACTMX3
Ontologies - Pathways
QuickGOQ96JJ7
Ontology : AmiGOprotein disulfide isomerase activity  protein binding  endoplasmic reticulum membrane  protein folding  cell surface  integral component of membrane  response to endoplasmic reticulum stress  cell redox homeostasis  
Ontology : EGO-EBIprotein disulfide isomerase activity  protein binding  endoplasmic reticulum membrane  protein folding  cell surface  integral component of membrane  response to endoplasmic reticulum stress  cell redox homeostasis  
NDEx NetworkTMX3
Atlas of Cancer Signalling NetworkTMX3
Wikipedia pathwaysTMX3
Orthology - Evolution
OrthoDB54495
GeneTree (enSembl)ENSG00000166479
Phylogenetic Trees/Animal Genes : TreeFamTMX3
HOVERGENQ96JJ7
HOGENOMQ96JJ7
Homologs : HomoloGeneTMX3
Homology/Alignments : Family Browser (UCSC)TMX3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMX3
dbVarTMX3
ClinVarTMX3
1000_GenomesTMX3 
Exome Variant ServerTMX3
ExAC (Exome Aggregation Consortium)TMX3 (select the gene name)
Genetic variants : HAPMAP54495
Genomic Variants (DGV)TMX3 [DGVbeta]
DECIPHER (Syndromes)18:66340925-66382353  ENSG00000166479
CONAN: Copy Number AnalysisTMX3 
Mutations
ICGC Data PortalTMX3 
TCGA Data PortalTMX3 
Broad Tumor PortalTMX3
OASIS PortalTMX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMX3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMX3
DgiDB (Drug Gene Interaction Database)TMX3
DoCM (Curated mutations)TMX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMX3 (select a term)
intoGenTMX3
Cancer3DTMX3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616102   
Orphanet
MedgenTMX3
Genetic Testing Registry TMX3
NextProtQ96JJ7 [Medical]
TSGene54495
GENETestsTMX3
Huge Navigator TMX3 [HugePedia]
snp3D : Map Gene to Disease54495
BioCentury BCIQTMX3
ClinGenTMX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54495
Chemical/Pharm GKB GenePA164726632
Clinical trialTMX3
Miscellaneous
canSAR (ICR)TMX3 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMX3
EVEXTMX3
GoPubMedTMX3
iHOPTMX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:49:14 CET 2017

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