TNFAIP2 (TNF alpha induced protein 2)

2003-06-01  

Identity

HGNC
LOCATION
14q32.32
LOCUSID
ALIAS
B94,EXOC3L3
FUSION GENES

Other Information

Locus ID:

NCBI: 7127
MIM: 603300
HGNC: 11895
Ensembl: ENSG00000185215

Variants:

dbSNP: 7127
ClinVar: 7127
TCGA: ENSG00000185215
COSMIC: TNFAIP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185215ENST00000333007Q03169
ENSG00000185215ENST00000558056H0YL88
ENSG00000185215ENST00000559255H0YKR7
ENSG00000185215ENST00000559406H0YKY9
ENSG00000185215ENST00000560562H0YKI8
ENSG00000185215ENST00000560670H0YLC0
ENSG00000185215ENST00000560869Q03169
ENSG00000185215ENST00000561156H0YM45

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
215555182011The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.60
261897982016KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2.36
219340932011A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck.32
206286242010Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".29
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
193392702009Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.24
210574572011A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma.23
239754272014NF-κB-mediated transcriptional upregulation of TNFAIP2 by the Epstein-Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma.21
237241092013The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer.13

Citation

Dessen P

TNFAIP2 (TNF alpha induced protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42599/tnfaip2