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TNFAIP6 (TNF alpha induced protein 6)

Identity

Alias_namestumor necrosis factor
Alias_symbol (synonym)TSG6
TSG-6
Other alias
HGNC (Hugo) TNFAIP6
LocusID (NCBI) 7130
Atlas_Id 42602
Location 2q23.3  [Link to chromosome band 2q23]
Location_base_pair Starts at 152214106 and ends at 152236562 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNFAIP6   11898
Cards
Entrez_Gene (NCBI)TNFAIP6  7130  TNF alpha induced protein 6
AliasesTSG-6; TSG6
GeneCards (Weizmann)TNFAIP6
Ensembl hg19 (Hinxton)ENSG00000123610 [Gene_View]  chr2:152214106-152236562 [Contig_View]  TNFAIP6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000123610 [Gene_View]  chr2:152214106-152236562 [Contig_View]  TNFAIP6 [Vega]
ICGC DataPortalENSG00000123610
TCGA cBioPortalTNFAIP6
AceView (NCBI)TNFAIP6
Genatlas (Paris)TNFAIP6
WikiGenes7130
SOURCE (Princeton)TNFAIP6
Genetics Home Reference (NIH)TNFAIP6
Genomic and cartography
GoldenPath hg19 (UCSC)TNFAIP6  -     chr2:152214106-152236562 +  2q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNFAIP6  -     2q23.3   [Description]    (hg38-Dec_2013)
EnsemblTNFAIP6 - 2q23.3 [CytoView hg19]  TNFAIP6 - 2q23.3 [CytoView hg38]
Mapping of homologs : NCBITNFAIP6 [Mapview hg19]  TNFAIP6 [Mapview hg38]
OMIM600410   
Gene and transcription
Genbank (Entrez)AF086484 AJ419936 AJ421518 AU102580 BC030205
RefSeq transcript (Entrez)NM_007115
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)TNFAIP6
Cluster EST : UnigeneHs.437322 [ NCBI ]
CGAP (NCI)Hs.437322
Alternative Splicing GalleryENSG00000123610
Gene ExpressionTNFAIP6 [ NCBI-GEO ]   TNFAIP6 [ EBI - ARRAY_EXPRESS ]   TNFAIP6 [ SEEK ]   TNFAIP6 [ MEM ]
Gene Expression Viewer (FireBrowse)TNFAIP6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7130
GTEX Portal (Tissue expression)TNFAIP6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98066   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP98066  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98066
Splice isoforms : SwissVarP98066
PhosPhoSitePlusP98066
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    LINK_1 (PS01241)    LINK_2 (PS50963)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin_fold    CUB_dom    Link_dom   
Domain families : Pfam (Sanger)CUB (PF00431)    Xlink (PF00193)   
Domain families : Pfam (NCBI)pfam00431    pfam00193   
Domain families : Smart (EMBL)CUB (SM00042)  LINK (SM00445)  
Conserved Domain (NCBI)TNFAIP6
DMDM Disease mutations7130
Blocks (Seattle)TNFAIP6
PDB (SRS)1O7B    1O7C    2N40    2PF5    2WNO   
PDB (PDBSum)1O7B    1O7C    2N40    2PF5    2WNO   
PDB (IMB)1O7B    1O7C    2N40    2PF5    2WNO   
PDB (RSDB)1O7B    1O7C    2N40    2PF5    2WNO   
Structural Biology KnowledgeBase1O7B    1O7C    2N40    2PF5    2WNO   
SCOP (Structural Classification of Proteins)1O7B    1O7C    2N40    2PF5    2WNO   
CATH (Classification of proteins structures)1O7B    1O7C    2N40    2PF5    2WNO   
SuperfamilyP98066
Human Protein AtlasENSG00000123610
Peptide AtlasP98066
HPRD02680
IPIIPI00303341   
Protein Interaction databases
DIP (DOE-UCLA)P98066
IntAct (EBI)P98066
FunCoupENSG00000123610
BioGRIDTNFAIP6
STRING (EMBL)TNFAIP6
ZODIACTNFAIP6
Ontologies - Pathways
QuickGOP98066
Ontology : AmiGOhyaluronic acid binding  inflammatory response  cell adhesion  signal transduction  cell-cell signaling  negative regulation of inflammatory response  
Ontology : EGO-EBIhyaluronic acid binding  inflammatory response  cell adhesion  signal transduction  cell-cell signaling  negative regulation of inflammatory response  
NDEx NetworkTNFAIP6
Atlas of Cancer Signalling NetworkTNFAIP6
Wikipedia pathwaysTNFAIP6
Orthology - Evolution
OrthoDB7130
GeneTree (enSembl)ENSG00000123610
Phylogenetic Trees/Animal Genes : TreeFamTNFAIP6
HOVERGENP98066
HOGENOMP98066
Homologs : HomoloGeneTNFAIP6
Homology/Alignments : Family Browser (UCSC)TNFAIP6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFAIP6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFAIP6
dbVarTNFAIP6
ClinVarTNFAIP6
1000_GenomesTNFAIP6 
Exome Variant ServerTNFAIP6
ExAC (Exome Aggregation Consortium)TNFAIP6 (select the gene name)
Genetic variants : HAPMAP7130
Genomic Variants (DGV)TNFAIP6 [DGVbeta]
DECIPHER (Syndromes)2:152214106-152236562  ENSG00000123610
CONAN: Copy Number AnalysisTNFAIP6 
Mutations
ICGC Data PortalTNFAIP6 
TCGA Data PortalTNFAIP6 
Broad Tumor PortalTNFAIP6
OASIS PortalTNFAIP6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFAIP6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNFAIP6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNFAIP6
DgiDB (Drug Gene Interaction Database)TNFAIP6
DoCM (Curated mutations)TNFAIP6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNFAIP6 (select a term)
intoGenTNFAIP6
Cancer3DTNFAIP6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600410   
Orphanet
MedgenTNFAIP6
Genetic Testing Registry TNFAIP6
NextProtP98066 [Medical]
TSGene7130
GENETestsTNFAIP6
Huge Navigator TNFAIP6 [HugePedia]
snp3D : Map Gene to Disease7130
BioCentury BCIQTNFAIP6
ClinGenTNFAIP6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7130
Chemical/Pharm GKB GenePA36595
Clinical trialTNFAIP6
Miscellaneous
canSAR (ICR)TNFAIP6 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNFAIP6
EVEXTNFAIP6
GoPubMedTNFAIP6
iHOPTNFAIP6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:22:52 CEST 2017

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