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TNFAIP8L2 (TNF alpha induced protein 8 like 2)

Identity

Alias_namestumor necrosis factor
Alias_symbol (synonym)FLJ23467
Other aliasTIPE2
HGNC (Hugo) TNFAIP8L2
LocusID (NCBI) 79626
Atlas_Id 43043
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151156629 and ends at 151159749 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PIP5K1A (1q21.3) / TNFAIP8L2 (1q21.3)TNFAIP8L2 (1q21.3) / SCNM1 (1q21.3)PIP5K1A 1q21.3 / TNFAIP8L2 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNFAIP8L2   26277
Cards
Entrez_Gene (NCBI)TNFAIP8L2  79626  TNF alpha induced protein 8 like 2
AliasesTIPE2
GeneCards (Weizmann)TNFAIP8L2
Ensembl hg19 (Hinxton)ENSG00000163154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163154 [Gene_View]  chr1:151156629-151159749 [Contig_View]  TNFAIP8L2 [Vega]
ICGC DataPortalENSG00000163154
TCGA cBioPortalTNFAIP8L2
AceView (NCBI)TNFAIP8L2
Genatlas (Paris)TNFAIP8L2
WikiGenes79626
SOURCE (Princeton)TNFAIP8L2
Genetics Home Reference (NIH)TNFAIP8L2
Genomic and cartography
GoldenPath hg38 (UCSC)TNFAIP8L2  -     chr1:151156629-151159749 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNFAIP8L2  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblTNFAIP8L2 - 1q21.3 [CytoView hg19]  TNFAIP8L2 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBITNFAIP8L2 [Mapview hg19]  TNFAIP8L2 [Mapview hg38]
OMIM612112   
Gene and transcription
Genbank (Entrez)AF271774 AF548003 AK027120 AK225472 AL833373
RefSeq transcript (Entrez)NM_024575
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNFAIP8L2
Cluster EST : UnigeneHs.744751 [ NCBI ]
CGAP (NCI)Hs.744751
Alternative Splicing GalleryENSG00000163154
Gene ExpressionTNFAIP8L2 [ NCBI-GEO ]   TNFAIP8L2 [ EBI - ARRAY_EXPRESS ]   TNFAIP8L2 [ SEEK ]   TNFAIP8L2 [ MEM ]
Gene Expression Viewer (FireBrowse)TNFAIP8L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79626
GTEX Portal (Tissue expression)TNFAIP8L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P589
Splice isoforms : SwissVarQ6P589
PhosPhoSitePlusQ6P589
Domains : Interpro (EBI)DUF758   
Domain families : Pfam (Sanger)DUF758 (PF05527)   
Domain families : Pfam (NCBI)pfam05527   
Conserved Domain (NCBI)TNFAIP8L2
DMDM Disease mutations79626
Blocks (Seattle)TNFAIP8L2
PDB (SRS)3F4M   
PDB (PDBSum)3F4M   
PDB (IMB)3F4M   
PDB (RSDB)3F4M   
Structural Biology KnowledgeBase3F4M   
SCOP (Structural Classification of Proteins)3F4M   
CATH (Classification of proteins structures)3F4M   
SuperfamilyQ6P589
Human Protein AtlasENSG00000163154
Peptide AtlasQ6P589
HPRD08029
IPIIPI00550948   
Protein Interaction databases
DIP (DOE-UCLA)Q6P589
IntAct (EBI)Q6P589
FunCoupENSG00000163154
BioGRIDTNFAIP8L2
STRING (EMBL)TNFAIP8L2
ZODIACTNFAIP8L2
Ontologies - Pathways
QuickGOQ6P589
Ontology : AmiGOprotein binding  cytoplasm  innate immune response  negative regulation of inflammatory response  negative regulation of T cell activation  
Ontology : EGO-EBIprotein binding  cytoplasm  innate immune response  negative regulation of inflammatory response  negative regulation of T cell activation  
NDEx NetworkTNFAIP8L2
Atlas of Cancer Signalling NetworkTNFAIP8L2
Wikipedia pathwaysTNFAIP8L2
Orthology - Evolution
OrthoDB79626
GeneTree (enSembl)ENSG00000163154
Phylogenetic Trees/Animal Genes : TreeFamTNFAIP8L2
HOVERGENQ6P589
HOGENOMQ6P589
Homologs : HomoloGeneTNFAIP8L2
Homology/Alignments : Family Browser (UCSC)TNFAIP8L2
Gene fusions - Rearrangements
Fusion : MitelmanPIP5K1A/TNFAIP8L2 [1q21.3/1q21.3]  [t(1;1)(q21;q21)]  
Fusion: TCGAPIP5K1A 1q21.3 TNFAIP8L2 1q21.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFAIP8L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFAIP8L2
dbVarTNFAIP8L2
ClinVarTNFAIP8L2
1000_GenomesTNFAIP8L2 
Exome Variant ServerTNFAIP8L2
ExAC (Exome Aggregation Consortium)TNFAIP8L2 (select the gene name)
Genetic variants : HAPMAP79626
Genomic Variants (DGV)TNFAIP8L2 [DGVbeta]
DECIPHERTNFAIP8L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNFAIP8L2 
Mutations
ICGC Data PortalTNFAIP8L2 
TCGA Data PortalTNFAIP8L2 
Broad Tumor PortalTNFAIP8L2
OASIS PortalTNFAIP8L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFAIP8L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNFAIP8L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNFAIP8L2
DgiDB (Drug Gene Interaction Database)TNFAIP8L2
DoCM (Curated mutations)TNFAIP8L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNFAIP8L2 (select a term)
intoGenTNFAIP8L2
Cancer3DTNFAIP8L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612112   
Orphanet
MedgenTNFAIP8L2
Genetic Testing Registry TNFAIP8L2
NextProtQ6P589 [Medical]
TSGene79626
GENETestsTNFAIP8L2
Target ValidationTNFAIP8L2
Huge Navigator TNFAIP8L2 [HugePedia]
snp3D : Map Gene to Disease79626
BioCentury BCIQTNFAIP8L2
ClinGenTNFAIP8L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79626
Chemical/Pharm GKB GenePA142670723
Clinical trialTNFAIP8L2
Miscellaneous
canSAR (ICR)TNFAIP8L2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNFAIP8L2
EVEXTNFAIP8L2
GoPubMedTNFAIP8L2
iHOPTNFAIP8L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:59:56 CEST 2017

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