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TNFAIP8L2 (TNF alpha induced protein 8 like 2)

Identity

Alias (NCBI)TIPE2
HGNC (Hugo) TNFAIP8L2
HGNC Alias symbFLJ23467
HGNC Previous nametumor necrosis factor, alpha-induced protein 8-like 2
LocusID (NCBI) 79626
Atlas_Id 43043
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151156649 and ends at 151159749 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PIP5K1A (1q21.3) / TNFAIP8L2 (1q21.3)TNFAIP8L2 (1q21.3) / SCNM1 (1q21.3)PIP5K1A 1q21.3 / TNFAIP8L2 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TNFAIP8L2   26277
Cards
Entrez_Gene (NCBI)TNFAIP8L2    TNF alpha induced protein 8 like 2
AliasesTIPE2
GeneCards (Weizmann)TNFAIP8L2
Ensembl hg19 (Hinxton)ENSG00000163154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163154 [Gene_View]  ENSG00000163154 [Sequence]  chr1:151156649-151159749 [Contig_View]  TNFAIP8L2 [Vega]
ICGC DataPortalENSG00000163154
TCGA cBioPortalTNFAIP8L2
AceView (NCBI)TNFAIP8L2
Genatlas (Paris)TNFAIP8L2
SOURCE (Princeton)TNFAIP8L2
Genetics Home Reference (NIH)TNFAIP8L2
Genomic and cartography
GoldenPath hg38 (UCSC)TNFAIP8L2  -     chr1:151156649-151159749 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNFAIP8L2  -     1q21.3   [Description]    (hg19-Feb_2009)
GoldenPathTNFAIP8L2 - 1q21.3 [CytoView hg19]  TNFAIP8L2 - 1q21.3 [CytoView hg38]
ImmunoBaseENSG00000163154
Genome Data Viewer NCBITNFAIP8L2 [Mapview hg19]  
OMIM612112   
Gene and transcription
Genbank (Entrez)AF271774 AF548003 AK027120 AK225472 AL833373
RefSeq transcript (Entrez)NM_024575
Consensus coding sequences : CCDS (NCBI)TNFAIP8L2
Gene ExpressionTNFAIP8L2 [ NCBI-GEO ]   TNFAIP8L2 [ EBI - ARRAY_EXPRESS ]   TNFAIP8L2 [ SEEK ]   TNFAIP8L2 [ MEM ]
Gene Expression Viewer (FireBrowse)TNFAIP8L2 [ Firebrowse - Broad ]
GenevisibleExpression of TNFAIP8L2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79626
GTEX Portal (Tissue expression)TNFAIP8L2
Human Protein AtlasENSG00000163154-TNFAIP8L2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P589
PhosPhoSitePlusQ6P589
Domains : Interpro (EBI)TNFAIP8-like    TNFAIP8_sf   
Domain families : Pfam (Sanger)DUF758 (PF05527)   
Domain families : Pfam (NCBI)pfam05527   
Conserved Domain (NCBI)TNFAIP8L2
PDB (RSDB)3F4M   
PDB Europe3F4M   
PDB (PDBSum)3F4M   
PDB (IMB)3F4M   
Structural Biology KnowledgeBase3F4M   
SCOP (Structural Classification of Proteins)3F4M   
CATH (Classification of proteins structures)3F4M   
SuperfamilyQ6P589
AlphaFold pdb e-kbQ6P589   
Human Protein Atlas [tissue]ENSG00000163154-TNFAIP8L2 [tissue]
HPRD08029
Protein Interaction databases
DIP (DOE-UCLA)Q6P589
IntAct (EBI)Q6P589
BioGRIDTNFAIP8L2
STRING (EMBL)TNFAIP8L2
ZODIACTNFAIP8L2
Ontologies - Pathways
QuickGOQ6P589
Ontology : AmiGOprotein binding  cytoplasm  regulation of apoptotic process  innate immune response  negative regulation of inflammatory response  negative regulation of T cell activation  
Ontology : EGO-EBIprotein binding  cytoplasm  regulation of apoptotic process  innate immune response  negative regulation of inflammatory response  negative regulation of T cell activation  
NDEx NetworkTNFAIP8L2
Atlas of Cancer Signalling NetworkTNFAIP8L2
Wikipedia pathwaysTNFAIP8L2
Orthology - Evolution
OrthoDB79626
GeneTree (enSembl)ENSG00000163154
Phylogenetic Trees/Animal Genes : TreeFamTNFAIP8L2
Homologs : HomoloGeneTNFAIP8L2
Homology/Alignments : Family Browser (UCSC)TNFAIP8L2
Gene fusions - Rearrangements
Fusion : MitelmanPIP5K1A/TNFAIP8L2 [1q21.3/1q21.3]  
Fusion : QuiverTNFAIP8L2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFAIP8L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFAIP8L2
dbVarTNFAIP8L2
ClinVarTNFAIP8L2
MonarchTNFAIP8L2
1000_GenomesTNFAIP8L2 
Exome Variant ServerTNFAIP8L2
GNOMAD BrowserENSG00000163154
Varsome BrowserTNFAIP8L2
ACMGTNFAIP8L2 variants
VarityQ6P589
Genomic Variants (DGV)TNFAIP8L2 [DGVbeta]
DECIPHERTNFAIP8L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNFAIP8L2 
Mutations
ICGC Data PortalTNFAIP8L2 
TCGA Data PortalTNFAIP8L2 
Broad Tumor PortalTNFAIP8L2
OASIS PortalTNFAIP8L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFAIP8L2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTNFAIP8L2
Mutations and Diseases : HGMDTNFAIP8L2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTNFAIP8L2
DgiDB (Drug Gene Interaction Database)TNFAIP8L2
DoCM (Curated mutations)TNFAIP8L2
CIViC (Clinical Interpretations of Variants in Cancer)TNFAIP8L2
Cancer3DTNFAIP8L2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612112   
Orphanet
DisGeNETTNFAIP8L2
MedgenTNFAIP8L2
Genetic Testing Registry TNFAIP8L2
NextProtQ6P589 [Medical]
GENETestsTNFAIP8L2
Target ValidationTNFAIP8L2
Huge Navigator TNFAIP8L2 [HugePedia]
ClinGenTNFAIP8L2
Clinical trials, drugs, therapy
MyCancerGenomeTNFAIP8L2
Protein Interactions : CTDTNFAIP8L2
Pharm GKB GenePA142670723
PharosQ6P589
Clinical trialTNFAIP8L2
Miscellaneous
canSAR (ICR)TNFAIP8L2
HarmonizomeTNFAIP8L2
DataMed IndexTNFAIP8L2
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTNFAIP8L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:41 CEST 2021

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