TNFAIP8L3 (TNF alpha induced protein 8 like 3)

2005-11-01  

Identity

HGNC
LOCATION
15q21.2
LOCUSID
ALIAS
TIPE3
FUSION GENES

Other Information

Locus ID:

NCBI: 388121
MIM: 616438
HGNC: 20620
Ensembl: ENSG00000183578

Variants:

dbSNP: 388121
ClinVar: 388121
TCGA: ENSG00000183578
COSMIC: TNFAIP8L3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183578ENST00000327536Q5GJ75
ENSG00000183578ENST00000637513A0A1B0GTK8
ENSG00000183578ENST00000649177A0A494C051

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380710982024Comprehensive analysis of the prognostic and immunological roles of TIPE3 in Colon Cancer.0
387597442024Down-regulated expression of TIPE3 inhibits malignant progression of non-small cell lung cancer via Wnt signaling.0
380710982024Comprehensive analysis of the prognostic and immunological roles of TIPE3 in Colon Cancer.0
387597442024Down-regulated expression of TIPE3 inhibits malignant progression of non-small cell lung cancer via Wnt signaling.0
367552222023Tumor necrosis factor-α-inducible protein 8-like protein 3 (TIPE3): a novel prognostic factor in colorectal cancer.1
368425652023TIPE3 protects mice from lipopolysaccharide-induced acute lung injury.1
370244532023TIPE3 represses head and neck squamous cell carcinoma progression via triggering PGAM5 mediated mitochondria dysfunction.5
367552222023Tumor necrosis factor-α-inducible protein 8-like protein 3 (TIPE3): a novel prognostic factor in colorectal cancer.1
368425652023TIPE3 protects mice from lipopolysaccharide-induced acute lung injury.1
370244532023TIPE3 represses head and neck squamous cell carcinoma progression via triggering PGAM5 mediated mitochondria dysfunction.5
350418352022Loss of TIPE3 reduced the proliferation, survival and migration of lung cancer cells through inactivation of Akt/mTOR, NF-κB, and STAT-3 signaling cascades.4
350418352022Loss of TIPE3 reduced the proliferation, survival and migration of lung cancer cells through inactivation of Akt/mTOR, NF-κB, and STAT-3 signaling cascades.4
319787702020Effects of the long and short isoforms of TIPE3 on the growth and metastasis of gastric cancer.7
319787702020Effects of the long and short isoforms of TIPE3 on the growth and metastasis of gastric cancer.7
306395322019TIPE3 is a regulator of cell apoptosis in glioblastoma.15

Citation

Dessen P

TNFAIP8L3 (TNF alpha induced protein 8 like 3)

Atlas Genet Cytogenet Oncol Haematol. 2005-11-01

Online version: http://atlasgeneticsoncology.org/gene/43044/tnfaip8l3