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TNFRSF14 (tumor necrosis factor receptor superfamily, member 14)

Identity

Other namesATAR
CD270
HVEA
HVEM
LIGHTR
TR2
HGNC (Hugo) TNFRSF14
LocusID (NCBI) 8764
Location 1p36.32
Location_base_pair Starts at 2487805 and ends at 2495267 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFRSF14   11912
Entrez_Gene (NCBI)TNFRSF14  8764  tumor necrosis factor receptor superfamily, member 14
Cards
GeneCards (Weizmann)TNFRSF14
Ensembl (Hinxton)ENSG00000157873 [Gene_View]  chr1:2487805-2495267 [Contig_View]  TNFRSF14 [Vega]
AceView (NCBI)TNFRSF14
Genatlas (Paris)TNFRSF14
SOURCE (Stanford)NM_003820
Genomic and cartography
GoldenPath (UCSC)TNFRSF14  -  1p36.32   chr1:2487805-2495267 +  1p36.32   [Description]    (hg19-Feb_2009)
EnsemblTNFRSF14 - 1p36.32 [CytoView]
Mapping of homologs : NCBITNFRSF14 [Mapview]
OMIM602746   
Gene and transcription
Genbank (Entrez)AB208808 AF153978 AF373877 AF373878 AK124010
RefSeq transcript (SRS)NM_003820
RefSeq transcript (Entrez)NM_003820
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NT_004350 NW_001838585 NW_004077988
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_004350 NW_001838585 NW_004077988
Consensus coding sequences : CCDS (NCBI)TNFRSF14
Cluster EST : UnigeneHs.512898 [ SRS ] Hs.512898 [ NCBI ]
CGAP (NCI)Hs.512898
Alternative Splicing : Fast-db (Paris)GSHG0000055
Alternative Splicing GalleryENSG00000157873
Gene ExpressionTNFRSF14 [ NCBI-GEO ]   TNFRSF14 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92956 (SRS) Q92956 (Uniprot)
NextProtQ92956
With graphics : InterProQ92956
Splice isoforms : SwissVarQ92956(Swissvar)
Domaine pattern : Prosite (SRS)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (SRS)TNFR/NGFR_Cys_rich_reg    TNFR_14   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_14   
Related proteins : CluSTrQ92956
Domain families : Pfam (SRS)TNFR_c6 (PF00020)   
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM8764
Blocks (Seattle)Q92956
PDB (SRS)1JMA    2AW2    4FHQ   
PDB (PDBSum)1JMA    2AW2    4FHQ   
PDB (IMB)1JMA    2AW2    4FHQ   
PDB (RSDB)1JMA    2AW2    4FHQ   
Human Protein AtlasENSG00000157873
HPRD04122
IPIIPI00024331   IPI00384412   IPI00911011   IPI00556085   IPI00916996   IPI00916056   IPI00916172   
Protein Interaction databases
DIP (DOE-UCLA)Q92956
IntAct (EBI)Q92956
FunCoupENSG00000157873
REACTOMETNFRSF14
Protein Interaction Database8764
BioGRIDTNFRSF14
InParanoidQ92956
Interologous Interaction database Q92956
IntegromeDBTNFRSF14
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNFRSF14
SNP (GeneSNP Utah)TNFRSF14
SNP : HGBaseTNFRSF14
Genetic variants : HAPMAPTNFRSF14
Cancer Gene: CensusTNFRSF14 
Somatic Mutations in Cancer : COSMICTNFRSF14 
CONAN: Copy Number AnalysisTNFRSF14 
Mutations and Diseases : HGMDTNFRSF14
OMIM602746   
GENETests602746   
Disease Genetic AssociationTNFRSF14
Huge Navigator TNFRSF14 [HugePedia]  TNFRSF14 [HugeCancerGEM]
Genomic VariantsTNFRSF14  TNFRSF14 [DGVbeta]
snp3D : Map Gene to Disease8764
General knowledge
Homologs : HomoloGeneTNFRSF14
Homology/Alignments : Family Browser (UCSC)TNFRSF14
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF14
Chemical/Protein Interactions : CTD8764
Chemical/Pharm GKB GenePA36605
Clinical trialTNFRSF14
Cancer Resource (Charite)ENSG00000157873
Ontology : AmiGOtumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral to plasma membrane  immune response  cell surface receptor signaling pathway  external side of plasma membrane  virus-host interaction  T cell costimulation  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  negative regulation of alpha-beta T cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  
Ontology : EGO-EBItumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral to plasma membrane  immune response  cell surface receptor signaling pathway  external side of plasma membrane  virus-host interaction  T cell costimulation  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  negative regulation of alpha-beta T cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  
Pathways : KEGGCytokine-cytokine receptor interaction
Other databases
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
PubGeneTNFRSF14
iHOPTNFRSF14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:47:59 CEST 2013
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