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TNFRSF14 (tumor necrosis factor receptor superfamily, member 14)

Identity

Other namesATAR
CD270
HVEA
HVEM
LIGHTR
TR2
HGNC (Hugo) TNFRSF14
LocusID (NCBI) 8764
Location 1p36.32
Location_base_pair Starts at 2487805 and ends at 2495267 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFRSF14   11912
Cards
Entrez_Gene (NCBI)TNFRSF14  8764  tumor necrosis factor receptor superfamily, member 14
GeneCards (Weizmann)TNFRSF14
Ensembl (Hinxton)ENSG00000157873 [Gene_View]  chr1:2487805-2495267 [Contig_View]  TNFRSF14 [Vega]
ICGC DataPortalENSG00000157873
cBioPortalTNFRSF14
AceView (NCBI)TNFRSF14
Genatlas (Paris)TNFRSF14
WikiGenes8764
SOURCE (Princeton)NM_003820
Genomic and cartography
GoldenPath (UCSC)TNFRSF14  -  1p36.32   chr1:2487805-2495267 +  1p36.32   [Description]    (hg19-Feb_2009)
EnsemblTNFRSF14 - 1p36.32 [CytoView]
Mapping of homologs : NCBITNFRSF14 [Mapview]
OMIM602746   
Gene and transcription
Genbank (Entrez)AB208808 AF153978 AF373877 AF373878 AK124010
RefSeq transcript (Entrez)NM_003820
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_004350 NW_001838585 NW_004929288
Consensus coding sequences : CCDS (NCBI)TNFRSF14
Cluster EST : UnigeneHs.512898 [ NCBI ]
CGAP (NCI)Hs.512898
Alternative Splicing : Fast-db (Paris)GSHG0000055
Alternative Splicing GalleryENSG00000157873
Gene ExpressionTNFRSF14 [ NCBI-GEO ]     TNFRSF14 [ SEEK ]   TNFRSF14 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92956 (Uniprot)
NextProtQ92956  [Medical]
With graphics : InterProQ92956
Splice isoforms : SwissVarQ92956 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg [organisation]   TNFR_14 [organisation]  
Related proteins : CluSTrQ92956
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM Disease mutations8764
Blocks (Seattle)Q92956
PDB (SRS)1JMA    2AW2    4FHQ   
PDB (PDBSum)1JMA    2AW2    4FHQ   
PDB (IMB)1JMA    2AW2    4FHQ   
PDB (RSDB)1JMA    2AW2    4FHQ   
Human Protein AtlasENSG00000157873 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ92956
HPRD04122
IPIIPI00024331   IPI00384412   IPI00911011   IPI00556085   IPI00916996   IPI00916056   IPI00916172   
Protein Interaction databases
DIP (DOE-UCLA)Q92956
IntAct (EBI)Q92956
FunCoupENSG00000157873
BioGRIDTNFRSF14
InParanoidQ92956
Interologous Interaction database Q92956
IntegromeDBTNFRSF14
STRING (EMBL)TNFRSF14
Ontologies - Pathways
Ontology : AmiGOvirus receptor activity  tumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral to plasma membrane  immune response  cell surface receptor signaling pathway  external side of plasma membrane  modulation by virus of host morphology or physiology  T cell costimulation  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  negative regulation of alpha-beta T cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  defense response to Gram-negative bacterium  defense response to Gram-positive bacterium  
Ontology : EGO-EBIvirus receptor activity  tumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral to plasma membrane  immune response  cell surface receptor signaling pathway  external side of plasma membrane  modulation by virus of host morphology or physiology  T cell costimulation  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  negative regulation of alpha-beta T cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  defense response to Gram-negative bacterium  defense response to Gram-positive bacterium  
Pathways : KEGGCytokine-cytokine receptor interaction    Herpes simplex infection   
Protein Interaction DatabaseTNFRSF14
Wikipedia pathwaysTNFRSF14
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNFRSF14
snp3D : Map Gene to Disease8764
SNP (GeneSNP Utah)TNFRSF14
SNP : HGBaseTNFRSF14
Genetic variants : HAPMAPTNFRSF14
Exome VariantTNFRSF14
1000_GenomesTNFRSF14 
ICGC programENSG00000157873 
Cancer Gene: CensusTNFRSF14 
Somatic Mutations in Cancer : COSMICTNFRSF14 
CONAN: Copy Number AnalysisTNFRSF14 
Mutations and Diseases : HGMDTNFRSF14
Genomic VariantsTNFRSF14  TNFRSF14 [DGVbeta]
dbVarTNFRSF14
ClinVarTNFRSF14
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602746   
MedgenTNFRSF14
GENETestsTNFRSF14
Disease Genetic AssociationTNFRSF14
Huge Navigator TNFRSF14 [HugePedia]  TNFRSF14 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTNFRSF14
Homology/Alignments : Family Browser (UCSC)TNFRSF14
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF14
Chemical/Protein Interactions : CTD8764
Chemical/Pharm GKB GenePA36605
Clinical trialTNFRSF14
Cancer Resource (Charite)ENSG00000157873
Other databases
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
CoreMineTNFRSF14
iHOPTNFRSF14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 17:23:19 CEST 2014

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