TNFRSF1A (tumor necrosis factor receptor superfamily, member 1A)

Identity

Other names	CD120a
	FPF
	MGC19588
	TBP1
	TNF-R
	TNF-R-I
	TNF-R55
	TNFAR
	TNFR1
	TNFR55
	TNFR60
	p55
	p55-R
	p60
HGNC	TNFRSF1A
Location	12p13.2
Location_base_pair	Starts at 6308184 and ends at 6321522 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TNFRSF1A   11916
Entrez_Gene	TNFRSF1A  7132  tumor necrosis factor receptor superfamily, member 1A
	Cards
GeneCards	TNFRSF1A
Ensembl	ENSG00000067182 [Gene_View]  TNFRSF1A [Vega]
Genatlas	TNFRSF1A
	Genomic and cartography
GoldenPath	TNFRSF1A  -  12p13.2   chr12:6308184-6321522 -  12p13.31   [Description]    (hg18-March_2006)
Ensembl	TNFRSF1A - 12p13.31 [CytoView]
NCBI	Mapview
OMIM	142680 Disease map [OMIM]
OMIM	191190 Disease map [OMIM]
HomoloGene	TNFRSF1A
	Gene and transcription
Genbank	A21522 [ ENTREZ ]
Genbank	AK056611 [ ENTREZ ]
Genbank	AK291088 [ ENTREZ ]
Genbank	AK298729 [ ENTREZ ]
Genbank	AK304517 [ ENTREZ ]
RefSeq	NM_001065 [ SRS ]    NM_001065 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NG_007506 [ SRS ]    NG_007506 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838050 [ SRS ]    NW_001838050 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
CCDS	TNFRSF1A CCDS - NCBI
AceView	TNFRSF1A AceView - NCBI
Unigene	Hs.713833 [ SRS ]    Hs.713833 [ NCBI ]
Fast-db	939 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P19438 [ SRS]    P19438 [ EXPASY ]     P19438 [ INTERPRO ]     P19438 [ UNIPROT ] P19438 [ VarSplice FASTA ]
Prosite	PS50017 DEATH_DOMAIN [ SRS ]    PS50017 DEATH_DOMAIN [ Expasy ]
Prosite	PS00652 TNFR_NGFR_1 [ SRS ]    PS00652 TNFR_NGFR_1 [ Expasy ]
Prosite	PS50050 TNFR_NGFR_2 [ SRS ]    PS50050 TNFR_NGFR_2 [ Expasy ]
Interpro	IPR000488 Death [ SRS ]    IPR000488 Death [ EBI ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
Interpro	IPR001368 TNFR_c6 [ SRS ]    IPR001368 TNFR_c6 [ EBI ]
CluSTr	P19438
Pfam	PF00531 Death [ SRS ]    PF00531 Death [ Sanger ]    pfam00531 [ NCBI-CDD ]
Pfam	PF00020 TNFR_c6 [ SRS ]    PF00020 TNFR_c6 [ Sanger ]    pfam00020 [ NCBI-CDD ]
Smart	SM00005 DEATH [EMBL]
Smart	SM00208 TNFR [EMBL]
Blocks	P19438
PDB	1EXT [ SRS ]    1EXT [ PdbSum ],   1EXT [ IMB ]   1EXT [ RSDB ]
PDB	1FT4 [ SRS ]    1FT4 [ PdbSum ],   1FT4 [ IMB ]   1FT4 [ RSDB ]
PDB	1ICH [ SRS ]    1ICH [ PdbSum ],   1ICH [ IMB ]   1ICH [ RSDB ]
PDB	1NCF [ SRS ]    1NCF [ PdbSum ],   1NCF [ IMB ]   1NCF [ RSDB ]
PDB	1TNR [ SRS ]    1TNR [ PdbSum ],   1TNR [ IMB ]   1TNR [ RSDB ]
HPRD	01861
	Protein Interaction databases
DIP	P19438
IntAct	P19438
	Polymorphism : SNP, mutations, diseases
OMIM	142680    [ map ]
OMIM	191190    [ map ]
GENETests	142680
GENETests	191190
SNP	TNFRSF1A [dbSNP-NCBI]
SNP	NM_001065 [SNP-NCI]
SNP	TNFRSF1A [GeneSNPs - Utah]  TNFRSF1A] [HGBASE - SRS]
HAPMAP	TNFRSF1A [HAPMAP]
COSMIC	TNFRSF1A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TNFRSF1A
Genetic Association	TNFRSF1A
CDC HuGE	TNFRSF1A
	General knowledge
Family Browser	TNFRSF1A [UCSC Family Browser]
SOURCE	NM_001065
SMD	Hs.713833
SAGE	Hs.713833
GO	receptor activity [Amigo]  receptor activity
GO	tumor necrosis factor receptor activity [Amigo]  tumor necrosis factor receptor activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	plasma membrane [Amigo]  plasma membrane
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	prostaglandin metabolic process [Amigo]  prostaglandin metabolic process
GO	apoptosis [Amigo]  apoptosis
GO	signal transduction [Amigo]  signal transduction
GO	cytokine and chemokine mediated signaling pathway [Amigo]  cytokine and chemokine mediated signaling pathway
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	interspecies interaction between organisms [Amigo]  interspecies interaction between organisms
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
GO	positive regulation of inflammatory response [Amigo]  positive regulation of inflammatory response
BIOCARTA	HIV-I Nef: negative effector of Fas and TNF    [Genes]
BIOCARTA	Acetylation and Deacetylation of RelA in The Nucleus    [Genes]
BIOCARTA	Ceramide Signaling Pathway    [Genes]
BIOCARTA	Keratinocyte Differentiation    [Genes]
BIOCARTA	NF-kB Signaling Pathway    [Genes]
BIOCARTA	Regulation of transcriptional activity by PML    [Genes]
BIOCARTA	SODD/TNFR1 Signaling Pathway    [Genes]
BIOCARTA	TNF/Stress Related Signaling    [Genes]
BIOCARTA	Chaperones modulate interferon Signaling Pathway    [Genes]
BIOCARTA	TNFR1 Signaling Pathway    [Genes]
KEGG	MAPK signaling pathway
KEGG	Cytokine-cytokine receptor interaction
KEGG	Apoptosis
KEGG	Adipocytokine signaling pathway
PubGene	TNFRSF1A
TreeFam	TNFRSF1A
CTD	7132 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TNFRSF1A Related clones (RZPD - Berlin)
	PubMed
PubMed	223 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:16:20 2008