Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TNFRSF1B (tumor necrosis factor receptor superfamily, member 1B)

Identity

Other namesCD120b
TBPII
TNF-R-II
TNF-R75
TNFBR
TNFR1B
TNFR2
TNFR80
p75
p75TNFR
HGNC (Hugo) TNFRSF1B
LocusID (NCBI) 7133
Location 1p36.22
Location_base_pair Starts at 12227060 and ends at 12269277 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFRSF1B   11917
Cards
Entrez_Gene (NCBI)TNFRSF1B  7133  tumor necrosis factor receptor superfamily, member 1B
GeneCards (Weizmann)TNFRSF1B
Ensembl (Hinxton)ENSG00000028137 [Gene_View]  chr1:12227060-12269277 [Contig_View]  TNFRSF1B [Vega]
ICGC DataPortalENSG00000028137
AceView (NCBI)TNFRSF1B
Genatlas (Paris)TNFRSF1B
WikiGenes7133
SOURCE (Princeton)NM_001066
Genomic and cartography
GoldenPath (UCSC)TNFRSF1B  -  1p36.22   chr1:12227060-12269277 +  1p36.22   [Description]    (hg19-Feb_2009)
EnsemblTNFRSF1B - 1p36.22 [CytoView]
Mapping of homologs : NCBITNFRSF1B [Mapview]
OMIM191191   
Gene and transcription
Genbank (Entrez)AY148473 BC011844 BC042167 BC052977 BT019927
RefSeq transcript (Entrez)NM_001066
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_029791 NT_032977 NW_001838534 NW_004929289
Consensus coding sequences : CCDS (NCBI)TNFRSF1B
Cluster EST : UnigeneHs.256278 [ NCBI ]
CGAP (NCI)Hs.256278
Alternative Splicing : Fast-db (Paris)GSHG0000133
Alternative Splicing GalleryENSG00000028137
Gene ExpressionTNFRSF1B [ NCBI-GEO ]     TNFRSF1B [ SEEK ]   TNFRSF1B [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20333 (Uniprot)
NextProtP20333  [Medical]
With graphics : InterProP20333
Splice isoforms : SwissVarP20333 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_1B   
Related proteins : CluSTrP20333
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM Disease mutations7133
Blocks (Seattle)P20333
PDB (SRS)1CA9    3ALQ   
PDB (PDBSum)1CA9    3ALQ   
PDB (IMB)1CA9    3ALQ   
PDB (RSDB)1CA9    3ALQ   
Human Protein AtlasENSG00000028137
Peptide AtlasP20333
HPRD01862
IPIIPI00023501   IPI00473089   IPI01009577   IPI00984120   IPI01011785   
Protein Interaction databases
DIP (DOE-UCLA)P20333
IntAct (EBI)P20333
FunCoupENSG00000028137
BioGRIDTNFRSF1B
InParanoidP20333
Interologous Interaction database P20333
IntegromeDBTNFRSF1B
STRING (EMBL)TNFRSF1B
Ontologies - Pathways
Ontology : AmiGOtumor necrosis factor-activated receptor activity  protein binding  extracellular region  nucleus  plasma membrane  inflammatory response  immune response  aging  intrinsic apoptotic signaling pathway in response to DNA damage  integral component of membrane  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  neuronal cell body  varicosity  membrane raft  perinuclear region of cytoplasm  negative regulation of inflammatory response  RNA destabilization  positive regulation of membrane protein ectodomain proteolysis  cellular response to lipopolysaccharide  cellular response to growth factor stimulus  
Ontology : EGO-EBItumor necrosis factor-activated receptor activity  protein binding  extracellular region  nucleus  plasma membrane  inflammatory response  immune response  aging  intrinsic apoptotic signaling pathway in response to DNA damage  integral component of membrane  ubiquitin protein ligase binding  tumor necrosis factor-mediated signaling pathway  neuronal cell body  varicosity  membrane raft  perinuclear region of cytoplasm  negative regulation of inflammatory response  RNA destabilization  positive regulation of membrane protein ectodomain proteolysis  cellular response to lipopolysaccharide  cellular response to growth factor stimulus  
Pathways : BIOCARTARegulation of transcriptional activity by PML [Genes]    SODD/TNFR1 Signaling Pathway [Genes]    TNFR2 Signaling Pathway [Genes]    Keratinocyte Differentiation [Genes]    Acetylation and Deacetylation of RelA in The Nucleus [Genes]    NF-kB Signaling Pathway [Genes]    Chaperones modulate interferon Signaling Pathway [Genes]    HIV-I Nef: negative effector of Fas and TNF [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    TNF signaling pathway    Adipocytokine signaling pathway    Amyotrophic lateral sclerosis (ALS)   
Protein Interaction DatabaseTNFRSF1B
Wikipedia pathwaysTNFRSF1B
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNFRSF1B
SNP (GeneSNP Utah)TNFRSF1B
SNP : HGBaseTNFRSF1B
Genetic variants : HAPMAPTNFRSF1B
1000_GenomesTNFRSF1B 
ICGC programENSG00000028137 
CONAN: Copy Number AnalysisTNFRSF1B 
Somatic Mutations in Cancer : COSMICTNFRSF1B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)TBsLVD Tuberculosis susceptibility Locus Variation Database
Mutations and Diseases : HGMDTNFRSF1B
OMIM191191   
MedgenTNFRSF1B
GENETestsTNFRSF1B
Disease Genetic AssociationTNFRSF1B
Huge Navigator TNFRSF1B [HugePedia]  TNFRSF1B [HugeCancerGEM]
Genomic VariantsTNFRSF1B  TNFRSF1B [DGVbeta]
Exome VariantTNFRSF1B
dbVarTNFRSF1B
ClinVarTNFRSF1B
snp3D : Map Gene to Disease7133
General knowledge
Homologs : HomoloGeneTNFRSF1B
Homology/Alignments : Family Browser (UCSC)TNFRSF1B
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF1B
Chemical/Protein Interactions : CTD7133
Chemical/Pharm GKB GenePA36610
Clinical trialTNFRSF1B
Cancer Resource (Charite)ENSG00000028137
Other databases
Probes
Litterature
PubMed355 Pubmed reference(s) in Entrez
CoreMineTNFRSF1B
iHOPTNFRSF1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:22:23 CEST 2014

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