Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7293
MIM: 600315
HGNC: 11918
Ensembl: ENSG00000186827
Variants:
dbSNP: 7293
ClinVar: 7293
TCGA: ENSG00000186827
COSMIC: TNFRSF4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186827 | ENST00000379236 | P43489 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37742913 | 2024 | Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines. | 0 |
| 38142184 | 2024 | Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women. | 0 |
| 38607026 | 2024 | An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis. | 1 |
| 37742913 | 2024 | Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines. | 0 |
| 38142184 | 2024 | Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women. | 0 |
| 38607026 | 2024 | An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis. | 1 |
| 36591653 | 2023 | Elevated expression of TNFRSF4 impacts immune cell infiltration and gene mutation in hepatocellular carcinoma. | 3 |
| 37932534 | 2023 | The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8(+) T-cell immunity. | 5 |
| 36591653 | 2023 | Elevated expression of TNFRSF4 impacts immune cell infiltration and gene mutation in hepatocellular carcinoma. | 3 |
| 37932534 | 2023 | The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8(+) T-cell immunity. | 5 |
| 34908008 | 2022 | DNA Methylation and mRNA Expression of OX40 (TNFRSF4) and GITR (TNFRSF18, AITR) in Head and Neck Squamous Cell Carcinoma Correlates With HPV Status, Mutational Load, an Interferon-γ Signature, Signatures of Immune Infiltrates, and Survival. | 6 |
| 35019224 | 2022 | The recurrent homozygous translation start site variant in CCDC134 in an individual with severe osteogenesis imperfecta of non-Morrocan ancestry. | 3 |
| 35265719 | 2022 | Clinical Significance of OX40 and OX40 Ligand in the Peripheral Blood of Patients with Myasthenia Gravis. | 0 |
| 35562682 | 2022 | Identification and validation of TNFRSF4 as a high-profile biomarker for prognosis and immunomodulation in endometrial carcinoma. | 8 |
| 36151238 | 2022 | Expression of the immune checkpoint modulator OX40 indicates poor survival in acute myeloid leukemia. | 5 |
Citation
Dessen P
TNFRSF4 (TNF receptor superfamily member 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42626/tnfrsf4
