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TNFRSF9 (tumor necrosis factor receptor superfamily, member 9)

Identity

Other names4-1BB
CD137
CDw137
ILA
HGNC (Hugo) TNFRSF9
LocusID (NCBI) 3604
Atlas_Id 42631
Location 1p36.23
Location_base_pair Starts at 7975931 and ends at 8003225 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFRSF9   11924
Cards
Entrez_Gene (NCBI)TNFRSF9  3604  tumor necrosis factor receptor superfamily, member 9
GeneCards (Weizmann)TNFRSF9
Ensembl hg19 (Hinxton)ENSG00000049249 [Gene_View]  chr1:7975931-8003225 [Contig_View]  TNFRSF9 [Vega]
Ensembl hg38 (Hinxton)ENSG00000049249 [Gene_View]  chr1:7975931-8003225 [Contig_View]  TNFRSF9 [Vega]
ICGC DataPortalENSG00000049249
TCGA cBioPortalTNFRSF9
AceView (NCBI)TNFRSF9
Genatlas (Paris)TNFRSF9
WikiGenes3604
SOURCE (Princeton)TNFRSF9
Genomic and cartography
GoldenPath hg19 (UCSC)TNFRSF9  -     chr1:7975931-8003225 -  1p36.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNFRSF9  -     1p36.23   [Description]    (hg38-Dec_2013)
EnsemblTNFRSF9 - 1p36.23 [CytoView hg19]  TNFRSF9 - 1p36.23 [CytoView hg38]
Mapping of homologs : NCBITNFRSF9 [Mapview hg19]  TNFRSF9 [Mapview hg38]
OMIM602250   
Gene and transcription
Genbank (Entrez)AK125490 AW449076 BC006196 BP381234 DQ892697
RefSeq transcript (Entrez)NM_001561
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)TNFRSF9
Cluster EST : UnigeneHs.738942 [ NCBI ]
CGAP (NCI)Hs.738942
Alternative Splicing : Fast-db (Paris)GSHG0001722
Alternative Splicing GalleryENSG00000049249
Gene ExpressionTNFRSF9 [ NCBI-GEO ]     TNFRSF9 [ SEEK ]   TNFRSF9 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ07011 (Uniprot)
NextProtQ07011  [Medical]
With graphics : InterProQ07011
Splice isoforms : SwissVarQ07011 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)Growth_fac_rcpt_N_dom    TNFR/NGFR_Cys_rich_reg    TNFR_9   
Related proteins : CluSTrQ07011
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM Disease mutations3604
Blocks (Seattle)Q07011
Human Protein AtlasENSG00000049249
Peptide AtlasQ07011
HPRD03767
IPIIPI00549343   
Protein Interaction databases
DIP (DOE-UCLA)Q07011
IntAct (EBI)Q07011
FunCoupENSG00000049249
BioGRIDTNFRSF9
IntegromeDBTNFRSF9
STRING (EMBL)TNFRSF9
Ontologies - Pathways
QuickGOQ07011
Ontology : AmiGOreceptor activity  extracellular space  integral component of plasma membrane  apoptotic process  negative regulation of cell proliferation  external side of plasma membrane  cytokine binding  protein homotrimerization  negative regulation of interleukin-10 secretion  negative regulation of interleukin-12 secretion  
Ontology : EGO-EBIreceptor activity  extracellular space  integral component of plasma membrane  apoptotic process  negative regulation of cell proliferation  external side of plasma membrane  cytokine binding  protein homotrimerization  negative regulation of interleukin-10 secretion  negative regulation of interleukin-12 secretion  
Pathways : BIOCARTAThe 4-1BB-dependent immune response [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction   
Protein Interaction DatabaseTNFRSF9
DoCM (Curated mutations)TNFRSF9
Wikipedia pathwaysTNFRSF9
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerTNFRSF9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFRSF9
dbVarTNFRSF9
ClinVarTNFRSF9
1000_GenomesTNFRSF9 
Exome Variant ServerTNFRSF9
SNP (GeneSNP Utah)TNFRSF9
SNP : HGBaseTNFRSF9
Genetic variants : HAPMAPTNFRSF9
Genomic Variants (DGV)TNFRSF9 [DGVbeta]
Mutations
ICGC Data PortalTNFRSF9 
TCGA Data PortalTNFRSF9 
Tumor PortalTNFRSF9
Somatic Mutations in Cancer : COSMICTNFRSF9 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:7975931-8003225
CONAN: Copy Number AnalysisTNFRSF9 
Mutations and Diseases : HGMDTNFRSF9
OMIM602250   
MedgenTNFRSF9
NextProtQ07011 [Medical]
GENETestsTNFRSF9
Disease Genetic AssociationTNFRSF9
Huge Navigator TNFRSF9 [HugePedia]  TNFRSF9 [HugeCancerGEM]
snp3D : Map Gene to Disease3604
DGIdb (Drug Gene Interaction db)TNFRSF9
General knowledge
Homologs : HomoloGeneTNFRSF9
Homology/Alignments : Family Browser (UCSC)TNFRSF9
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF9
Chemical/Protein Interactions : CTD3604
Chemical/Pharm GKB GenePA36617
Clinical trialTNFRSF9
Cancer Resource (Charite)ENSG00000049249
Other databases
Probes
Litterature
PubMed99 Pubmed reference(s) in Entrez
CoreMineTNFRSF9
GoPubMedTNFRSF9
iHOPTNFRSF9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 20:14:05 CEST 2015

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