TNFSF12 (tumor necrosis factor (ligand) superfamily, member 12)

Identity

Other names	APO3L
	DR3LG
	MGC129581
	MGC20669
	TWEAK
HGNC	TNFSF12
Location	17p13.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TNFSF12   11927
Entrez_Gene	TNFSF12  8742  tumor necrosis factor (ligand) superfamily, member 12
	Cards
GeneCards	TNFSF12
Ensembl	TNFSF12 [Search_View]   ENSG00000161955 [Gene_View]
Genatlas	TNFSF12
GeneLynx	TNFSF12
eGenome	TNFSF12
euGene	8742
	Genomic and cartography
GoldenPath	TNFSF12  -  17p13.1   chr17:7393099-7401931 +  17p13.1   [Description]    (hg18-March_2006)
Ensembl	TNFSF12 - 17p13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TNFSF12
	Gene and transcription
Genbank	AF030099 [ ENTREZ ]
Genbank	AF055872 [ ENTREZ ]
Genbank	AY358870 [ ENTREZ ]
Genbank	BC019047 [ ENTREZ ]
Genbank	BC071837 [ ENTREZ ]
RefSeq	NM_003809 [ SRS ]    NM_003809 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	TNFSF12 AceView - NCBI
Unigene	Hs.54673 [ SRS ]    Hs.54673 [ NCBI ]     HS54673 [ spliceNest ]
Fast-db	3073 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O43508 [ SRS]    O43508 [ EXPASY ]     O43508 [ INTERPRO ]     O43508 [ UNIPROT ]
Prosite	PS00251 TNF_1 [ SRS ]    PS00251 TNF_1 [ Expasy ]
Prosite	PS50049 TNF_2 [ SRS ]    PS50049 TNF_2 [ Expasy ]
Interpro	IPR006052 TNF_family [ SRS ]    IPR006052 TNF_family [ EBI ]
Interpro	IPR008983 Tumour_necrosis_fac-like [ SRS ]    IPR008983 Tumour_necrosis_fac-like [ EBI ]
CluSTr	O43508
Pfam	PF00229 TNF [ SRS ]    PF00229 TNF [ Sanger ]    pfam00229 [ NCBI-CDD ]
Smart	SM00207 TNF [EMBL]
Blocks	O43508
HPRD	04074
	Protein Interaction databases
DIP	O43508
IntAct	O43508
	Polymorphism : SNP, mutations, diseases
OMIM	602695    [ map ]
GENECLINICS	602695
SNP	TNFSF12 [dbSNP-NCBI]
SNP	NM_003809 [SNP-NCI]
SNP	TNFSF12 [GeneSNPs - Utah]  TNFSF12] [HGBASE - SRS]
HAPMAP	TNFSF12 [HAPMAP]
HGMD	TNFSF12
	General knowledge
Family Browser	TNFSF12 [UCSC Family Browser]
SOURCE	NM_003809
SMD	Hs.54673
SAGE	Hs.54673
GO	positive regulation of endothelial cell proliferation [Amigo]  positive regulation of endothelial cell proliferation
GO	cytokine activity [Amigo]  cytokine activity
GO	tumor necrosis factor receptor binding [Amigo]  tumor necrosis factor receptor binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	apoptosis [Amigo]  apoptosis
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	immune response [Amigo]  immune response
GO	signal transduction [Amigo]  signal transduction
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	cell differentiation [Amigo]  cell differentiation
GO	endothelial cell migration [Amigo]  endothelial cell migration
GO	positive regulation of angiogenesis [Amigo]  positive regulation of angiogenesis
GO	perinuclear region of cytoplasm [Amigo]  perinuclear region of cytoplasm
PubGene	TNFSF12
TreeFam	TNFSF12
CTD	8742 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TNFSF12 Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 18:26:21 2008