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TNFSF13 (tumor necrosis factor (ligand) superfamily, member 13)

Identity

Other namesAPRIL
CD256
TALL-2
TALL2
TRDL-1
ZTNF2
HGNC (Hugo) TNFSF13
LocusID (NCBI) 8741
Location 17p13.1
Location_base_pair Starts at 7461609 and ends at 7464925 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFSF13   11928
Cards
Entrez_Gene (NCBI)TNFSF13  8741  tumor necrosis factor (ligand) superfamily, member 13
GeneCards (Weizmann)TNFSF13
Ensembl (Hinxton)ENSG00000161955 [Gene_View]  chr17:7461609-7464925 [Contig_View]  TNFSF13 [Vega]
ICGC DataPortalENSG00000161955
AceView (NCBI)TNFSF13
Genatlas (Paris)TNFSF13
WikiGenes8741
SOURCE (Princeton)NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088
Genomic and cartography
GoldenPath (UCSC)TNFSF13  -  17p13.1   chr17:7461609-7464925 +  17p13.1   [Description]    (hg19-Feb_2009)
EnsemblTNFSF13 - 17p13.1 [CytoView]
Mapping of homologs : NCBITNFSF13 [Mapview]
OMIM604472   
Gene and transcription
Genbank (Entrez)AF046888 AF114011 AF114012 AF114013 AF136294
RefSeq transcript (Entrez)NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_029949 NT_010718 NW_001838403 NW_004929405
Consensus coding sequences : CCDS (NCBI)TNFSF13
Cluster EST : UnigeneHs.54673 [ NCBI ]
CGAP (NCI)Hs.54673
Alternative Splicing : Fast-db (Paris)GSHG0012197
Alternative Splicing GalleryENSG00000161955
Gene ExpressionTNFSF13 [ NCBI-GEO ]     TNFSF13 [ SEEK ]   TNFSF13 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75888 (Uniprot)
NextProtO75888  [Medical]
With graphics : InterProO75888
Splice isoforms : SwissVarO75888 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNF_1 (PS00251)    TNF_2 (PS50049)   
Domains : Interpro (EBI)TNF_CS    TNF_dom    Tumour_necrosis_fac-like_dom   
Related proteins : CluSTrO75888
Domain families : Pfam (Sanger)TNF (PF00229)   
Domain families : Pfam (NCBI)pfam00229   
Domain families : Smart (EMBL)TNF (SM00207)  
DMDM Disease mutations8741
Blocks (Seattle)O75888
Human Protein AtlasENSG00000161955
Peptide AtlasO75888
Protein Interaction databases
DIP (DOE-UCLA)O75888
IntAct (EBI)O75888
FunCoupENSG00000161955
BioGRIDTNFSF13
IntegromeDBTNFSF13
STRING (EMBL)TNFSF13
Ontologies - Pathways
QuickGOO75888
Ontology : AmiGOimmunoglobulin production in mucosal tissue  positive regulation of germinal center formation  receptor binding  cytokine activity  tumor necrosis factor receptor binding  extracellular space  nucleoplasm  cytoplasm  cytosol  signal transduction  positive regulation of cell proliferation  external side of plasma membrane  gene expression  RNA metabolic process  mRNA metabolic process  positive regulation of isotype switching to IgA isotypes  extracellular vesicular exosome  
Ontology : EGO-EBIimmunoglobulin production in mucosal tissue  positive regulation of germinal center formation  receptor binding  cytokine activity  tumor necrosis factor receptor binding  extracellular space  nucleoplasm  cytoplasm  cytosol  signal transduction  positive regulation of cell proliferation  external side of plasma membrane  gene expression  RNA metabolic process  mRNA metabolic process  positive regulation of isotype switching to IgA isotypes  extracellular vesicular exosome  
Pathways : BIOCARTATACI and BCMA stimulation of B cell immune responses. [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    Intestinal immune network for IgA production    Rheumatoid arthritis   
Protein Interaction DatabaseTNFSF13
Wikipedia pathwaysTNFSF13
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNFSF13
SNP (GeneSNP Utah)TNFSF13
SNP : HGBaseTNFSF13
Genetic variants : HAPMAPTNFSF13
1000_GenomesTNFSF13 
ICGC programENSG00000161955 
CONAN: Copy Number AnalysisTNFSF13 
Somatic Mutations in Cancer : COSMICTNFSF13 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)17:7461609-7464925
Mutations and Diseases : HGMDTNFSF13
OMIM604472   
MedgenTNFSF13
GENETestsTNFSF13
Disease Genetic AssociationTNFSF13
Huge Navigator TNFSF13 [HugePedia]  TNFSF13 [HugeCancerGEM]
Genomic VariantsTNFSF13  TNFSF13 [DGVbeta]
Exome VariantTNFSF13
dbVarTNFSF13
ClinVarTNFSF13
snp3D : Map Gene to Disease8741
General knowledge
Homologs : HomoloGeneTNFSF13
Homology/Alignments : Family Browser (UCSC)TNFSF13
Phylogenetic Trees/Animal Genes : TreeFamTNFSF13
Chemical/Protein Interactions : CTD8741
Chemical/Pharm GKB GenePA36621
Clinical trialTNFSF13
Cancer Resource (Charite)ENSG00000161955
Other databases
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
CoreMineTNFSF13
GoPubMedTNFSF13
iHOPTNFSF13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:02:18 CET 2014

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