Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TNFSF14 (tumor necrosis factor (ligand) superfamily, member 14)

Identity

Other namesCD258
HVEML
LIGHT
LTg
TR2
HGNC (Hugo) TNFSF14
LocusID (NCBI) 8740
Location 19p13.3
Location_base_pair Starts at 6663148 and ends at 6670599 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNFSF14   11930
Cards
Entrez_Gene (NCBI)TNFSF14  8740  tumor necrosis factor (ligand) superfamily, member 14
GeneCards (Weizmann)TNFSF14
Ensembl (Hinxton)ENSG00000125735 [Gene_View]  chr19:6663148-6670599 [Contig_View]  TNFSF14 [Vega]
ICGC DataPortalENSG00000125735
cBioPortalTNFSF14
AceView (NCBI)TNFSF14
Genatlas (Paris)TNFSF14
WikiGenes8740
SOURCE (Princeton)NM_003807 NM_172014
Genomic and cartography
GoldenPath (UCSC)TNFSF14  -  19p13.3   chr19:6663148-6670599 -  19p13.3   [Description]    (hg19-Feb_2009)
EnsemblTNFSF14 - 19p13.3 [CytoView]
Mapping of homologs : NCBITNFSF14 [Mapview]
OMIM604520   
Gene and transcription
Genbank (Entrez)AF036581 AF064090 AK026704 AK292037 AY028261
RefSeq transcript (Entrez)NM_003807 NM_172014
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011295 NW_001838478 NW_004929412
Consensus coding sequences : CCDS (NCBI)TNFSF14
Cluster EST : UnigeneHs.129708 [ NCBI ]
CGAP (NCI)Hs.129708
Alternative Splicing : Fast-db (Paris)GSHG0015424
Alternative Splicing GalleryENSG00000125735
Gene ExpressionTNFSF14 [ NCBI-GEO ]     TNFSF14 [ SEEK ]   TNFSF14 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43557 (Uniprot)
NextProtO43557  [Medical]
With graphics : InterProO43557
Splice isoforms : SwissVarO43557 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNF_2 (PS50049)   
Domains : Interpro (EBI)TNF [organisation]   TNF_dom [organisation]   Tumour_necrosis_fac-like_dom [organisation]  
Related proteins : CluSTrO43557
Domain families : Pfam (Sanger)TNF (PF00229)   
Domain families : Pfam (NCBI)pfam00229   
Domain families : Smart (EMBL)TNF (SM00207)  
DMDM Disease mutations8740
Blocks (Seattle)O43557
PDB (SRS)4EN0    4J6G    4KG8    4KGG    4KGQ   
PDB (PDBSum)4EN0    4J6G    4KG8    4KGG    4KGQ   
PDB (IMB)4EN0    4J6G    4KG8    4KGG    4KGQ   
PDB (RSDB)4EN0    4J6G    4KG8    4KGG    4KGQ   
Human Protein AtlasENSG00000125735 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO43557
HPRD05157
IPIIPI00307531   IPI00221341   
Protein Interaction databases
DIP (DOE-UCLA)O43557
IntAct (EBI)O43557
FunCoupENSG00000125735
BioGRIDTNFSF14
InParanoidO43557
Interologous Interaction database O43557
IntegromeDBTNFSF14
STRING (EMBL)TNFSF14
Ontologies - Pathways
Ontology : AmiGOreceptor binding  cytokine activity  tumor necrosis factor receptor binding  protein binding  extracellular space  cytoplasm  plasma membrane  apoptotic process  immune response  signal transduction  release of cytoplasmic sequestered NF-kappaB  positive regulation of T cell chemotaxis  integral component of membrane  T cell costimulation  T cell proliferation  T cell activation  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  T cell homeostasis  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  cellular response to mechanical stimulus  
Ontology : EGO-EBIreceptor binding  cytokine activity  tumor necrosis factor receptor binding  protein binding  extracellular space  cytoplasm  plasma membrane  apoptotic process  immune response  signal transduction  release of cytoplasmic sequestered NF-kappaB  positive regulation of T cell chemotaxis  integral component of membrane  T cell costimulation  T cell proliferation  T cell activation  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  T cell homeostasis  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  cellular response to mechanical stimulus  
Pathways : KEGGCytokine-cytokine receptor interaction    NF-kappa B signaling pathway    Herpes simplex infection   
Protein Interaction DatabaseTNFSF14
Wikipedia pathwaysTNFSF14
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNFSF14
snp3D : Map Gene to Disease8740
SNP (GeneSNP Utah)TNFSF14
SNP : HGBaseTNFSF14
Genetic variants : HAPMAPTNFSF14
Exome VariantTNFSF14
1000_GenomesTNFSF14 
ICGC programENSG00000125735 
Somatic Mutations in Cancer : COSMICTNFSF14 
CONAN: Copy Number AnalysisTNFSF14 
Mutations and Diseases : HGMDTNFSF14
Mutations and Diseases : intOGenTNFSF14
Genomic VariantsTNFSF14  TNFSF14 [DGVbeta]
dbVarTNFSF14
ClinVarTNFSF14
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM604520   
MedgenTNFSF14
GENETestsTNFSF14
Disease Genetic AssociationTNFSF14
Huge Navigator TNFSF14 [HugePedia]  TNFSF14 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTNFSF14
Homology/Alignments : Family Browser (UCSC)TNFSF14
Phylogenetic Trees/Animal Genes : TreeFamTNFSF14
Chemical/Protein Interactions : CTD8740
Chemical/Pharm GKB GenePA36622
Clinical trialTNFSF14
Cancer Resource (Charite)ENSG00000125735
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
CoreMineTNFSF14
iHOPTNFSF14
OncoSearchTNFSF14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:22:53 CEST 2014

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