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TNFSF8 (TNF superfamily member 8)

Identity

Alias_namesCD30LG
tumor necrosis factor (ligand) superfamily
Alias_symbol (synonym)CD153
Other aliasCD30L
TNLG3A
HGNC (Hugo) TNFSF8
LocusID (NCBI) 944
Atlas_Id 42644
Location 9q33.1  [Link to chromosome band 9q33]
Location_base_pair Starts at 114901145 and ends at 114930595 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

4TD WMDtH=15%>CIViC (Clinical Interpretations of Variants in Cancer)
Nomenclature
HGNC (Hugo)TNFSF8   11938
Cards
Entrez_Gene (NCBI)TNFSF8  944  TNF superfamily member 8
AliasesCD153; CD30L; CD30LG; TNLG3A
GeneCards (Weizmann)TNFSF8
Ensembl hg19 (Hinxton)ENSG00000106952 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106952 [Gene_View]  chr9:114901145-114930595 [Contig_View]  TNFSF8 [Vega]
ICGC DataPortalENSG00000106952
TCGA cBioPortalTNFSF8
AceView (NCBI)TNFSF8
Genatlas (Paris)TNFSF8
WikiGenes944
SOURCE (Princeton)TNFSF8
Genetics Home Reference (NIH)TNFSF8
Genomic and cartography
GoldenPath hg38 (UCSC)TNFSF8  -     chr9:114901145-114930595 -  9q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNFSF8  -     9q33.1   [Description]    (hg19-Feb_2009)
EnsemblTNFSF8 - 9q33.1 [CytoView hg19]  TNFSF8 - 9q33.1 [CytoView hg38]
Mapping of homologs : NCBITNFSF8 [Mapview hg19]  TNFSF8 [Mapview hg38]
OMIM603875   
Gene and transcription
Genbank (Entrez)AA748015 AK313619 AL583443 AW118787 BC093630
RefSeq transcript (Entrez)NM_001244 NM_001252290
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNFSF8
Cluster EST : UnigeneHs.654445 [ NCBI ]
CGAP (NCI)Hs.654445
Alternative Splicing GalleryENSG00000106952
Gene ExpressionTNFSF8 [ NCBI-GEO ]   TNFSF8 [ EBI - ARRAY_EXPRESS ]   TNFSF8 [ SEEK ]   TNFSF8 [ MEM ]
Gene Expression Viewer (FireBrowse)TNFSF8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)944
GTEX Portal (Tissue expression)TNFSF8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32971   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32971  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32971
Splice isoforms : SwissVarP32971
PhosPhoSitePlusP32971
Domaine pattern : Prosite (Expaxy)TNF_1 (PS00251)    TNF_2 (PS50049)   
Domains : Interpro (EBI)TNF_CD30_ligand_type    TNF_CS    TNF_dom    Tumour_necrosis_fac-like_dom   
Domain families : Pfam (Sanger)TNF (PF00229)   
Domain families : Pfam (NCBI)pfam00229   
Domain families : Smart (EMBL)TNF (SM00207)  
Conserved Domain (NCBI)TNFSF8
DMDM Disease mutations944
Blocks (Seattle)TNFSF8
SuperfamilyP32971
Human Protein AtlasENSG00000106952
Peptide AtlasP32971
HPRD04852
IPIIPI00031715   
Protein Interaction databases
DIP (DOE-UCLA)P32971
IntAct (EBI)P32971
FunCoupENSG00000106952
BioGRIDTNFSF8
STRING (EMBL)TNFSF8
ZODIACTNFSF8
Ontologies - Pathways
QuickGOP32971
Ontology : AmiGOreceptor binding  cytokine activity  tumor necrosis factor receptor binding  extracellular space  plasma membrane  integral component of plasma membrane  apoptotic process  immune response  signal transduction  cell-cell signaling  cell proliferation  tumor necrosis factor-mediated signaling pathway  CD8-positive, alpha-beta T cell differentiation  positive regulation of transcription from RNA polymerase II promoter  defense response to Gram-positive bacterium  
Ontology : EGO-EBIreceptor binding  cytokine activity  tumor necrosis factor receptor binding  extracellular space  plasma membrane  integral component of plasma membrane  apoptotic process  immune response  signal transduction  cell-cell signaling  cell proliferation  tumor necrosis factor-mediated signaling pathway  CD8-positive, alpha-beta T cell differentiation  positive regulation of transcription from RNA polymerase II promoter  defense response to Gram-positive bacterium  
Pathways : KEGGCytokine-cytokine receptor interaction   
NDEx NetworkTNFSF8
Atlas of Cancer Signalling NetworkTNFSF8
Wikipedia pathways
Orthology - Evolution
OrthoDB944
GeneTree (enSembl)ENSG00000106952
Phylogenetic Trees/Animal Genes : TreeFamTNFSF8
HOVERGENP32971
HOGENOMP32971
Homologs : HomoloGeneTNFSF8
Homology/Alignments : Family Browser (UCSC)TNFSF8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFSF8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFSF8
dbVarTNFSF8
ClinVarTNFSF8
1000_GenomesTNFSF8 
Exome Variant ServerTNFSF8
ExAC (Exome Aggregation Consortium)TNFSF8 (select the gene name)
Genetic variants : HAPMAP944
Genomic Variants (DGV)TNFSF8 [DGVbeta]
DECIPHERTNFSF8 [patients] &nbs`; [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNFSF8 
Mutations
ICGC Data PortalTNFSF8 
TCGA Data PortalTNFSF8 
Broad Tumor PortalTNFSF8
OASIS PortalTNFSF8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFSF8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNFSF8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNFSF8
DgiDB (Drug Gene Interaction Database)TNFSF8
DoCM (Curated mutations)TNFSF8 (select the gene name)
TNFSF8 (select a term)
intoGenTNFSF8
Cancer3DTNFSF8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603875   
Orphanet
MedgenTNFSF8
Genetic Testing Registry TNFSF8
NextProtP32971 [Medical]
TSGene944
GENETestsTNFSF8
Target ValidationTNFSF8
Huge Navigator TNFSF8 [HugePedia]
snp3D : Map Gene to Disease944
BioCentury BCIQTNFSF8
ClinGenTNFSF8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD944
Chemical/Pharm GKB GenePA36628
Clinical trialTNFSF8
Miscellaneous
canSAR (ICR)TNFSF8 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNFSF8
EVEXTNFSF8
GoPubMedTNFSF8
iHOPTNFSF8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:35:42 CEST 2017

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