Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
4-1BB-L,CD137L,TNLG5A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8744
MIM: 606182
HGNC: 11939
Ensembl: ENSG00000125657
Variants:
dbSNP: 8744
ClinVar: 8744
TCGA: ENSG00000125657
COSMIC: TNFSF9
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125657 | ENST00000245817 | P41273 |
| ENSG00000125657 | ENST00000245817 | A0A0U5J8I0 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38344886 | 2024 | Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke. | 0 |
| 38344886 | 2024 | Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke. | 0 |
| 34902807 | 2022 | Feedback regulation of antioxidant transcription factor NFE2L1 and immunostimulatory factor 41BBL mediates the crosstalk between oxidative stress and tumor immunity. | 4 |
| 35714694 | 2022 | Role of TNFSF9 bidirectional signal transduction in antitumor immunotherapy. | 4 |
| 35812455 | 2022 | Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB. | 7 |
| 34902807 | 2022 | Feedback regulation of antioxidant transcription factor NFE2L1 and immunostimulatory factor 41BBL mediates the crosstalk between oxidative stress and tumor immunity. | 4 |
| 35714694 | 2022 | Role of TNFSF9 bidirectional signal transduction in antitumor immunotherapy. | 4 |
| 35812455 | 2022 | Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB. | 7 |
| 32077004 | 2021 | TNFSF9 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Pancreatic Cancer. | 12 |
| 33572150 | 2021 | Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis. | 4 |
| 34207500 | 2021 | 4-1BBL as a Mediator of Cross-Talk between Innate, Adaptive, and Regulatory Immunity against Cancer. | 6 |
| 34517345 | 2021 | TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages. | 11 |
| 32077004 | 2021 | TNFSF9 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Pancreatic Cancer. | 12 |
| 33572150 | 2021 | Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis. | 4 |
| 34207500 | 2021 | 4-1BBL as a Mediator of Cross-Talk between Innate, Adaptive, and Regulatory Immunity against Cancer. | 6 |
Citation
Dessen P
TNFSF9 (TNF superfamily member 9)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42645/tnfsf9
