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TNIP1 (TNFAIP3 interacting protein 1)

Identity

Alias_symbol (synonym)NAF1
KIAA0113
ABIN-1
VAN
Other aliasnip40-1
HGNC (Hugo) TNIP1
LocusID (NCBI) 10318
Atlas_Id 50501
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 151029943 and ends at 151081084 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GRIP1 (12q14.3) / TNIP1 (5q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)TNIP1   16903
Cards
Entrez_Gene (NCBI)TNIP1  10318  TNFAIP3 interacting protein 1
AliasesABIN-1; NAF1; VAN; nip40-1
GeneCards (Weizmann)TNIP1
Ensembl hg19 (Hinxton)ENSG00000145901 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145901 [Gene_View]  chr5:151029943-151081084 [Contig_View]  TNIP1 [Vega]
ICGC DataPortalENSG00000145901
TCGA cBioPortalTNIP1
AceView (NCBI)TNIP1
Genatlas (Paris)TNIP1
WikiGenes10318
SOURCE (Princeton)TNIP1
Genetics Home Reference (NIH)TNIP1
Genomic and cartography
GoldenPath hg38 (UCSC)TNIP1  -     chr5:151029943-151081084 -  5q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNIP1  -     5q33.1   [Description]    (hg19-Feb_2009)
EnsemblTNIP1 - 5q33.1 [CytoView hg19]  TNIP1 - 5q33.1 [CytoView hg38]
Mapping of homologs : NCBITNIP1 [Mapview hg19]  TNIP1 [Mapview hg38]
OMIM607714   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001252385 NM_001252386 NM_001252390 NM_001252391 NM_001252392 NM_001252393 NM_001258454 NM_001258455 NM_001258456 NM_006058
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNIP1
Cluster EST : UnigeneHs.731557 [ NCBI ]
CGAP (NCI)Hs.731557
Alternative Splicing GalleryENSG00000145901
Gene ExpressionTNIP1 [ NCBI-GEO ]   TNIP1 [ EBI - ARRAY_EXPRESS ]   TNIP1 [ SEEK ]   TNIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)TNIP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10318
GTEX Portal (Tissue expression)TNIP1
Human Protein AtlasENSG00000145901-TNIP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15025   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15025  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15025
Splice isoforms : SwissVarQ15025
PhosPhoSitePlusQ15025
Domains : Interpro (EBI)CC2-LZ_dom    TNIP1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TNIP1
DMDM Disease mutations10318
Blocks (Seattle)TNIP1
SuperfamilyQ15025
Human Protein Atlas [tissue]ENSG00000145901-TNIP1 [tissue]
Peptide AtlasQ15025
HPRD09216
IPIIPI00783750   IPI00216616   IPI01009625   IPI00982171   IPI00975498   IPI00979742   IPI00807702   IPI00976307   IPI00977305   IPI00977259   IPI00975558   
Protein Interaction databases
DIP (DOE-UCLA)Q15025
IntAct (EBI)Q15025
FunCoupENSG00000145901
BioGRIDTNIP1
STRING (EMBL)TNIP1
ZODIACTNIP1
Ontologies - Pathways
QuickGOQ15025
Ontology : AmiGOMyD88-dependent toll-like receptor signaling pathway  thiol-dependent ubiquitin-specific protease activity  protein binding  intracellular  nucleoplasm  cytosol  cytosol  translation  defense response  inflammatory response  leukocyte cell-cell adhesion  glycoprotein biosynthetic process  protein deubiquitination  identical protein binding  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of viral genome replication  positive regulation of transcription from RNA polymerase II promoter  positive regulation of inflammatory response  mitogen-activated protein kinase binding  negative regulation of ERK1 and ERK2 cascade  modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade  
Ontology : EGO-EBIMyD88-dependent toll-like receptor signaling pathway  thiol-dependent ubiquitin-specific protease activity  protein binding  intracellular  nucleoplasm  cytosol  cytosol  translation  defense response  inflammatory response  leukocyte cell-cell adhesion  glycoprotein biosynthetic process  protein deubiquitination  identical protein binding  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of viral genome replication  positive regulation of transcription from RNA polymerase II promoter  positive regulation of inflammatory response  mitogen-activated protein kinase binding  negative regulation of ERK1 and ERK2 cascade  modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade  
NDEx NetworkTNIP1
Atlas of Cancer Signalling NetworkTNIP1
Wikipedia pathwaysTNIP1
Orthology - Evolution
OrthoDB10318
GeneTree (enSembl)ENSG00000145901
Phylogenetic Trees/Animal Genes : TreeFamTNIP1
HOVERGENQ15025
HOGENOMQ15025
Homologs : HomoloGeneTNIP1
Homology/Alignments : Family Browser (UCSC)TNIP1
Gene fusions - Rearrangements
Fusion : MitelmanGRIP1/TNIP1 [12q14.3/5q33.1]  [t(5;12)(q33;q14)]  
Tumor Fusion PortalTNIP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNIP1
dbVarTNIP1
ClinVarTNIP1
1000_GenomesTNIP1 
Exome Variant ServerTNIP1
ExAC (Exome Aggregation Consortium)ENSG00000145901
GNOMAD BrowserENSG00000145901
Genetic variants : HAPMAP10318
Genomic Variants (DGV)TNIP1 [DGVbeta]
DECIPHERTNIP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNIP1 
Mutations
ICGC Data PortalTNIP1 
TCGA Data PortalTNIP1 
Broad Tumor PortalTNIP1
OASIS PortalTNIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNIP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNIP1
DgiDB (Drug Gene Interaction Database)TNIP1
DoCM (Curated mutations)TNIP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNIP1 (select a term)
intoGenTNIP1
Cancer3DTNIP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607714   
Orphanet
DisGeNETTNIP1
MedgenTNIP1
Genetic Testing Registry TNIP1
NextProtQ15025 [Medical]
TSGene10318
GENETestsTNIP1
Target ValidationTNIP1
Huge Navigator TNIP1 [HugePedia]
snp3D : Map Gene to Disease10318
BioCentury BCIQTNIP1
ClinGenTNIP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10318
Chemical/Pharm GKB GenePA128394573
Clinical trialTNIP1
Miscellaneous
canSAR (ICR)TNIP1 (select the gene name)
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNIP1
EVEXTNIP1
GoPubMedTNIP1
iHOPTNIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 21:03:32 CET 2017

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