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TNIP2 (TNFAIP3 interacting protein 2)

Identity

Other namesABIN2
FLIP1
KLIP
HGNC (Hugo) TNIP2
LocusID (NCBI) 79155
Location 4p16.3
Location_base_pair Starts at 2743387 and ends at 2757752 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNIP2   19118
Entrez_Gene (NCBI)TNIP2  79155  TNFAIP3 interacting protein 2
Cards
GeneCards (Weizmann)TNIP2
Ensembl (Hinxton)ENSG00000168884 [Gene_View]  chr4:2743387-2757752 [Contig_View]  TNIP2 [Vega]
AceView (NCBI)TNIP2
Genatlas (Paris)TNIP2
SOURCE (Stanford)NM_001161527 NM_024309
Genomic and cartography
GoldenPath (UCSC)TNIP2  -  4p16.3   chr4:2743387-2757752 -  4p16.3   [Description]    (hg19-Feb_2009)
EnsemblTNIP2 - 4p16.3 [CytoView]
Mapping of homologs : NCBITNIP2 [Mapview]
OMIM610669   
Gene and transcription
Genbank (Entrez)AF372839 AJ304866 AK026176 AK096296 AL137262
RefSeq transcript (SRS)NM_001161527 NM_024309
RefSeq transcript (Entrez)NM_001161527 NM_024309
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_006051 NW_001838896 NW_004078016
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_006051 NW_001838896 NW_004078016
Consensus coding sequences : CCDS (NCBI)TNIP2
Cluster EST : UnigeneHs.368551 [ SRS ] Hs.368551 [ NCBI ]
CGAP (NCI)Hs.368551
Alternative Splicing : Fast-db (Paris)GSHG0023081
Alternative Splicing GalleryENSG00000168884
Gene ExpressionTNIP2 [ NCBI-GEO ]   TNIP2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFZ5 (SRS) Q8NFZ5 (Uniprot)
NextProtQ8NFZ5
With graphics : InterProQ8NFZ5
Splice isoforms : SwissVarQ8NFZ5(Swissvar)
Domains : Interpro (SRS)EABR   
Domains : Interpro (EBI)EABR   
Related proteins : CluSTrQ8NFZ5
Domain families : Pfam (SRS)EABR (PF12180)   
Domain families : Pfam (Sanger)EABR (PF12180)   
Domain families : Pfam (NCBI)pfam12180   
DMDM79155
Blocks (Seattle)Q8NFZ5
Human Protein AtlasENSG00000168884
HPRD18207
IPIIPI00168953   IPI00884948   IPI00967179   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFZ5
IntAct (EBI)Q8NFZ5
FunCoupENSG00000168884
REACTOMETNIP2
Protein Interaction Database79155
BioGRIDTNIP2
InParanoidQ8NFZ5
Interologous Interaction database Q8NFZ5
IntegromeDBTNIP2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TNIP2
SNP (GeneSNP Utah)TNIP2
SNP : HGBaseTNIP2
Genetic variants : HAPMAPTNIP2
Somatic Mutations in Cancer : COSMICTNIP2 
CONAN: Copy Number AnalysisTNIP2 
Mutations and Diseases : HGMDTNIP2
OMIM610669   
GENETests610669   
Disease Genetic AssociationTNIP2
Huge Navigator TNIP2 [HugePedia]  TNIP2 [HugeCancerGEM]
Genomic VariantsTNIP2  TNIP2 [DGVbeta]
snp3D : Map Gene to Disease79155
General knowledge
Homologs : HomoloGeneTNIP2
Homology/Alignments : Family Browser (UCSC)TNIP2
Phylogenetic Trees/Animal Genes : TreeFamTNIP2
Chemical/Protein Interactions : CTD79155
Chemical/Pharm GKB GenePA134957006
Clinical trialTNIP2
Cancer Resource (Charite)ENSG00000168884
Ontology : AmiGOprotein binding  nucleus  cytosol  transcription, DNA-dependent  apoptotic process  inflammatory response  I-kappaB kinase/NF-kappaB cascade  protein kinase binding  CD40 signaling pathway  polyubiquitin binding  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 9 signaling pathway  positive regulation of macrophage activation  positive regulation of I-kappaB kinase/NF-kappaB cascade  positive regulation of transcription from RNA polymerase II promoter  protein stabilization  positive regulation of B cell activation  interleukin-1-mediated signaling pathway  cellular response to lipopolysaccharide  negative regulation of endothelial cell apoptotic process  
Ontology : EGO-EBIprotein binding  nucleus  cytosol  transcription, DNA-dependent  apoptotic process  inflammatory response  I-kappaB kinase/NF-kappaB cascade  protein kinase binding  CD40 signaling pathway  polyubiquitin binding  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 9 signaling pathway  positive regulation of macrophage activation  positive regulation of I-kappaB kinase/NF-kappaB cascade  positive regulation of transcription from RNA polymerase II promoter  protein stabilization  positive regulation of B cell activation  interleukin-1-mediated signaling pathway  cellular response to lipopolysaccharide  negative regulation of endothelial cell apoptotic process  
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
PubGeneTNIP2
iHOPTNIP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:40:44 CEST 2013
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