TNK1 (tyrosine kinase, non-receptor, 1)

Identity

Other names	MGC46193
HGNC	TNK1
Location	17p13.1
Location_base_pair	Starts at 7225089 and ends at 7233816 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TNK1   11940
Entrez_Gene	TNK1  8711  tyrosine kinase, non-receptor, 1
	Cards
GeneCards	TNK1
Ensembl	TNK1 [Search_View]   ENSG00000174292 [Gene_View]
Genatlas	TNK1
GeneLynx	TNK1
eGenome	TNK1
euGene	8711
	Genomic and cartography
GoldenPath	TNK1  -  17p13.1   chr17:7225089-7233816 +  17p13.1   [Description]    (hg18-March_2006)
Ensembl	TNK1 - 17p13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TNK1
	Gene and transcription
Genbank	AI810287 [ ENTREZ ]
Genbank	AK225403 [ ENTREZ ]
Genbank	AK310684 [ ENTREZ ]
Genbank	BC035782 [ ENTREZ ]
Genbank	CR623896 [ ENTREZ ]
RefSeq	NM_003985 [ SRS ]    NM_003985 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	TNK1 AceView - NCBI
Unigene	Hs.203420 [ SRS ]    Hs.203420 [ NCBI ]     HS203420 [ spliceNest ]
Fast-db	2950 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q13470 [ SRS]    Q13470 [ EXPASY ]     Q13470 [ INTERPRO ]     Q13470 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00109 PROTEIN_KINASE_TYR [ SRS ]    PS00109 PROTEIN_KINASE_TYR [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR001245 Tyr_pkinase [ SRS ]    IPR001245 Tyr_pkinase [ EBI ]
Interpro	IPR008266 Tyr_pkinase_AS [ SRS ]    IPR008266 Tyr_pkinase_AS [ EBI ]
Interpro	IPR015772 Tyrosine_kinase_TNK1 [ SRS ]    IPR015772 Tyrosine_kinase_TNK1 [ EBI ]
CluSTr	Q13470
Pfam	PF07714 Pkinase_Tyr [ SRS ]    PF07714 Pkinase_Tyr [ Sanger ]    pfam07714 [ NCBI-CDD ]
Smart	SM00326 SH3 [EMBL]
Smart	SM00219 TyrKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q13470 TNK1_HUMAN [ Domain structure ]   Q13470 TNK1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q13470
HPRD	09730
	Protein Interaction databases
DIP	Q13470
IntAct	Q13470
	Polymorphism : SNP, mutations, diseases
OMIM	608076    [ map ]
GENECLINICS	608076
SNP	TNK1 [dbSNP-NCBI]
SNP	NM_003985 [SNP-NCI]
SNP	TNK1 [GeneSNPs - Utah]  TNK1] [HGBASE - SRS]
HAPMAP	TNK1 [HAPMAP]
COSMIC	TNK1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TNK1
	General knowledge
Family Browser	TNK1 [UCSC Family Browser]
SOURCE	NM_003985
SMD	Hs.203420
SAGE	Hs.203420
Enzyme	2.7.10.2 [ Enzyme-Expasy ]   2.7.10.2 [ Enzyme-SRS ]   2.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   2.7.10.2 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	non-membrane spanning protein tyrosine kinase activity [Amigo]  non-membrane spanning protein tyrosine kinase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	membrane [Amigo]  membrane
GO	transferase activity [Amigo]  transferase activity
GO	protein amino acid autophosphorylation [Amigo]  protein amino acid autophosphorylation
PubGene	TNK1
TreeFam	TNK1
CTD	8711 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TNK1 Related clones (RZPD - Berlin)
	PubMed
PubMed	9 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:35:46 2008