TNK1 (tyrosine kinase non receptor 1)

2006-10-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
KOS1
FUSION GENES

Other Information

Locus ID:

NCBI: 8711
MIM: 608076
HGNC: 11940
Ensembl: ENSG00000174292

Variants:

dbSNP: 8711
ClinVar: 8711
TCGA: ENSG00000174292
COSMIC: TNK1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174292ENST00000570896Q13470
ENSG00000174292ENST00000576207U3KPR9
ENSG00000174292ENST00000576716I3L334
ENSG00000174292ENST00000576812Q13470

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377768572023Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.0
377768572023Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.0
363346232022The noncatalytic regions of the tyrosine kinase Tnk1 are important for activity and substrate specificity.4
363346232022The noncatalytic regions of the tyrosine kinase Tnk1 are important for activity and substrate specificity.4
330702672021Polymorphism rs11867353 of Tyrosine Kinase Non-Receptor 1 (TNK1) Gene Is a Novel Genetic Marker for Alzheimer's Disease.1
345041012021TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.11
330702672021Polymorphism rs11867353 of Tyrosine Kinase Non-Receptor 1 (TNK1) Gene Is a Novel Genetic Marker for Alzheimer's Disease.1
345041012021TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.11
329831602020Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock.8
329831602020Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock.8
286311882018Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.10
303206002018Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.20
286311882018Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.10
303206002018Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.20
244498622014Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1.21

Citation

Dessen P

TNK1 (tyrosine kinase non receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43533/tnk1